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argJ

Victor ID 89
Gene Name argJ
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885125
NCBI Protein GI 15608791
Locus Tag Rv1653
Protein Accession NP_216169.1
Other Database IDs UniProtKB-ID: ARGJ_MYCTU
UniRef100: UniRef100_P63572
UniRef90: UniRef90_P63572
UniRef50: UniRef50_Q4JW03
UniParc: UPI00000D1075
EMBL: BX842577
EMBL: AE000516
EMBL-CDS: CAB06647.1
EMBL-CDS: AAK45960.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 3IT4
PDB: 3IT6
MEROPS: T05.001
EnsemblGenome: EBMYCG00000001793
EnsemblGenome_TRS: EBMYCT00000001795
EnsemblGenome_PRO: EBMYCP00000001795
EnsemblGenome: EBMYCG00000073064
EnsemblGenome_TRS: EBMYCT00000073069
EnsemblGenome_PRO: EBMYCP00000071128
Geno
Taxonomy ID 83332
Gene Starting Position 1866630
Gene Ending Position 1867844
Gene Strand (Orientation) +
Protein Name bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein
DNA Sequence 
>gi|57116681:1866630-1867844 Mycobacterium tuberculosis H37Rv, complete genome
CGTGACCGACCTGGCCGGCACCACCCGGCTGCTGCGCGCTCAGGGCGTCACCGCCCCGGCCGGCTTTCGG
GCCGCCGGCGTCGCCGCCGGGATCAAGGCCTCCGGTGCGCTGGATCTGGCGCTGGTGTTCAACGAGGGAC
CCGACTACGCCGCCGCCGGGGTGTTCACCCGCAACCAGGTCAAGGCGGCGCCGGTGCTGTGGACCCAGCA
AGTGCTGACCACCGGGCGGCTGCGCGCGGTGATCCTCAACTCCGGCGGCGCCAATGCCTGCACCGGGCCG
GCCGGCTTCGCCGACACCCACGCCACCGCGGAGGCGGTGGCCGCGGCGTTGTCGGACTGGGGAACCGAGA
CCGGGGCCATCGAGGTCGCCGTCTGCTCCACCGGGCTGATCGGCGACCGGCTGCCGATGGACAAGCTGCT
CGCCGGCGTCGCCCACGTGGTGCACGAGATGCATGGCGGGCTGGTCGGCGGCGATGAAGCCGCCCACGCC
ATCATGACCACCGACAACGTGCCCAAACAGGTTGCGCTGCACCATCACGACAACTGGACGGTCGGCGGCA
TGGCCAAAGGCGCGGGCATGCTGGCGCCGTCGTTGGCCACCATGCTGTGCGTGCTCACCACCGACGCGGC
CGCCGAGCCGGCCGCACTCGAGCGGGCGCTGCGCCGCGCCGCCGCGGCCACGTTCGACCGGCTCGACATC
GACGGCAGCTGCTCCACCAACGACACCGTGCTGCTGCTGTCGTCCGGGGCCAGTGAAATCCCCCCTGCCC
AGGCCGATCTCGACGAGGCCGTGCTACGGGTCTGCGACGATTTGTGCGCCCAGCTGCAGGCCGACGCCGA
AGGCGTCACCAAACGCGTCACCGTGACCGTGACCGGGGCCGCCACCGAAGACGACGCGCTGGTCGCCGCC
CGCCAGATCGCCCGCGACAGCCTGGTCAAGACCGCGCTGTTCGGGTCCGACCCGAACTGGGGACGGGTGC
TCGCCGCCGTCGGGATGGCACCGATCACCCTCGACCCGGATCGAATCAGCGTGTCGTTCAACGGTGCCGC
GGTGTGTGTGCACGGTGTCGGCGCTCCCGGTGCGCGCGAGGTGGACCTGTCGGACGCGGACATCGATATC
ACCGTCGACCTCGGCGTCGGCGACGGGCAGGCGAGGATCCGAACCACTGATCTGTCGCATGCCTACGTCG
AAGAGAACTCGGCCTACAGCTCATG
Protein Sequence 
>gi|15608791|ref|NP_216169.1| bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase [Mycobacterium tuberculosis H37Rv] MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1364E, under E: Amino acid transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].