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spa33 from Shigella flexneri 2a str. 301

Victor ID 889
Gene Name spa33 from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238000
NCBI Protein GI 31983540
Locus Tag CP0152
Protein Accession NP_858285.1
Other Database IDs UniProtKB-ID: SPAO_SHIFL
UniRef100: UniRef100_P0A1K9
UniRef90: UniRef90_P0A1K9
UniRef50: UniRef50_P0A1K9
UniParc: UPI0000135DA0
EMBL: M81458
EMBL: D13663
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: AAA26543.1
EMBL-CDS: BAA02828.1
EMBL-CDS: CAC05827.1
EMBL-CDS: AAK18471.1
EMBL-CDS: AAL72304.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093078
EnsemblGenome_TRS: EBESCT00000094034
EnsemblGenome_PRO: EBESCP00000090241
GenomeReviews: AF386526_GR
KEGG: sfl:CP0152
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 131943
Gene Ending Position 132689
Gene Strand (Orientation) +
Protein Name Spa33, component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|31983523:131943-132689 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
CGTGTGTGGGGATTGGGTAATTCGTATTGATACATTATCTTTTTTGAAAAAAAAATACGAGGTATTTTCA
GGATTTTCTACACAAGAATCTTTACTGCATTTATCAAAATGTGTCTTTATAGAGTCGTCATCTGTATTTT
CGATTCCAGAACTGTCTGATAAGATTACTTTCCGGATCACGAATGAAATCCAGTATGCAACTACTGGGAG
TCATTTATGCTGTTTTTCCTCTTCTTTAGGTATTATTTATTTTGACAAGATGCCGGTATTACGTAATCAA
GTTTCTCTTGACTCATTGCATCATCTTTTAGAGTTTTGCTTAGGTTCATCTAATGTAAGGCTGGCTACTT
TAAAAAGAATTCGCACTGGTGATATAATCATAGTTCAGAAACTTTATAATTTATTATTGTGTAATCAAGT
TATTATTGGGGATTATATTGTGAATGATAATAATGAGGCAAAAATTAATCTGTCAGAAAGTAATGGTGAG
TCAGAACACACAGAAGTTTCTTTGGCATTATTCAATTATGATGATATCAATGTAAAAGTGGACTTTATTC
TTTTAGAAAAAAATATGACAATCAATGAACTAAAAATGTATGTAGAAAACGAATTATTCAAGTTTCCCGA
TGACATAGTTAAACATGTAAATATTAAAGTAAATGGTTCTTTGGTTGGGCATGGGGAACTTGTTTCTATT
GAGGATGGTTATGGTATCGAGATTAGTTCTTGGATGGTAAAGGAGTA
Protein Sequence 
>gi|31983540|ref|NP_858285.1| Mxi-Spa secretion machinery protein Spa33 [Shigella flexneri 2a str. 301] MCGDWVIRIDTLSFLKKKYEVFSGFSTQESLLHLSKCVFIESSSVFSIPELSDKITFRITNEIQYATTGSHLCCFSSSLGIIYFDKMPVLRNQVSLDSLHHLLEFCLGSSNVRLATLKRIRTGDIIIVQKLYNLLLCNQVIIGDYIVNDNNEAKINLSESNGESEHTEVSLALFNYDDINVKVDFILLEKNMTINELKMYVENELFKFPDDIVKHVNIKVNGSLVGHGELVSIEDGYGIEISSWMVKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spa33 mutants are unable to secrete effectors necessary to cell invasion (Morita-Ishihara et al., 2006).
COG COG1886NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Morita-Ishihara et al., 2006: Morita-Ishihara T, Ogawa M, Sagara H, Yoshida M, Katayama E, Sasakawa C. Shigella Spa33 is an essential C-ring component of type III secretion machinery. The Journal of biological chemistry. 2006; 281(1); 599-607. [PubMed: 16246841].