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virB from Shigella flexneri 2a str. 301

Victor ID 886
Gene Name virB from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1237991
NCBI Protein GI 31983531
Locus Tag CP0123
Protein Accession NP_858256.1
Other Database IDs UniProtKB-ID: VIRB_SHIFL
UniRef100: UniRef100_P0A247
UniRef90: UniRef90_P0A247
UniRef50: UniRef50_P0A247
UniParc: UPI0000000B47
EMBL: X14340
EMBL: AL391753
EMBL: AF348706
EMBL: AY206439
EMBL: AF386526
EMBL-CDS: CAA32525.1
EMBL-CDS: CAC05798.1
EMBL-CDS: AAK18441.1
EMBL-CDS: AAP78986.1
EMBL-CDS: AAL72295.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093070
EnsemblGenome_TRS: EBESCT00000094026
EnsemblGenome_PRO: EBESCP00000090233
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 105791
Gene Ending Position 106720
Gene Strand (Orientation) -
Protein Name VirB, transcriptional activator required for tanscription of the ipa, mxi, and spa operons
DNA Sequence 
>gi|31983523:105791-106720 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
TTTATGAAGACGATAGATGGCGAGAAATTATATCCCGAATAGCTTCATCTATTTCTCTCTGAACTGTTTT
GTTTATTTTAGATAATGTAAATATTAGAGTTCTGTTTGTTTTATTCTCTTTTCTTTTTATGTAAGTCCGT
TTGTCTTTAGAAATAAATAACGAGTCAACTTTTAGCGAAGGGTTTTGCTTTCTGTTTTTGCTTTTCTTTA
TGATGTTTAAAATTTCTTTTTTATATATGTCCGGGGGCAAATTTGTATCAAGGTCTTTTATTTCTTCCTT
TAATATTGGTAGTGTAGAACTAAGAGATTCATTAGCCTTTTCAAGTCCTTTATAATAATTGAATAATATC
TTGTAGTCATTAAAGTTAAGTTCTGACGCGATTGGAAATAGAGATATTATTTCCTGTGGAACGCTTGCTG
CCTGAAAGGCACGAGTGACTTTCGCGCGAGACAGATTCTCTTTTTTGGCTATGTCTTTATAGGACATCCC
TGATACTTTCAGAAAATTAAGACCAATACCAAGTTCTCGGATGCTATGCTCTTTTGCTGTTTGTATATCG
TTTGCTAGTTTTCTGGCATCAAGAGTAGATATATATTCTTTTGAATATAGAACTTCAAGATCTGCTCCTG
CATATATTGCAGATGCTCTTCTACGAGTGCCATCCAGAATTTCAATTCTACCATCAATCTCCCTTCCTAT
TACAGGGAAGAATTGTTGTAGCTTTATAGTTTTTATGATATCGGCTAATGATTCTTCTGTTAGGGATTCT
TGATCGCGTACATTCGTTTTTTGGTTGACGAAGGTTAAATCTTGGATCCTTTTATGAGGAATCTTGGCTT
TGATAAAGGAAACTTTATTACCAGAATGGAGTGTAAACTCTTTCTTTTGGCCTTCCTTTATACTTAACAA
GTCGTTGCACAAATCCACCA
Protein Sequence 
>gi|31983531|ref|NP_858256.1| transcriptional activator VirB [Shigella flexneri 2a str. 301] MVDLCNDLLSIKEGQKKEFTLHSGNKVSFIKAKIPHKRIQDLTFVNQKTNVRDQESLTEESLADIIKTIKLQQFFPVIGREIDGRIEILDGTRRRASAIYAGADLEVLYSKEYISTLDARKLANDIQTAKEHSIRELGIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEIISLFPIASELNFNDYKILFNYYKGLEKANESLSSTLPILKEEIKDLDTNLPPDIYKKEILNIIKKSKNRKQNPSLKVDSLFISKDKRTYIKRKENKTNRTLIFTLSKINKTVQREIDEAIRDIISRHLSSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virB mutants have an avirulent phenotype and do not invade host cells (Sasakawa et al., 1993).
COG COG1475K, under K: Transcription
References
Sasakawa et al., 1993: Sasakawa C, Komatsu K, Tobe T, Suzuki T, Yoshikawa M. Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. Journal of bacteriology. 1993; 175(8); 2334-2346. [PubMed: 8385666].