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ompC from Shigella flexneri 2a str. 301

Victor ID 882
Gene Name ompC from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1026756
NCBI Protein GI 24113600
Locus Tag SF2299
Protein Accession NP_708110.1
Other Database IDs UniProtKB-ID: Q83QU7_SHIFL
UniRef100: UniRef100_Q0T2R1
UniRef90: UniRef90_Q8CVW1
UniRef50: UniRef50_Q56828
UniParc: UPI000000E3D2
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAN43817.1
EMBL-CDS: AAP17634.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
HSSP: Q48473
EnsemblGenome: EBESCG00000087747.
EnsemblGenome_TRS: EBESCT00000088703
EnsemblGenome_PRO: EBESCP00000085525
EnsemblGenome: EBESCG00000092107.
EnsemblGenome_TRS: EBESCT00000093063
EnsemblGenome_PRO: EBESCP00000089699
GenomeReviews: AE005674
Taxonomy ID 198214
Gene Starting Position 2333031
Gene Ending Position 2334152
Gene Strand (Orientation) -
Protein Name outer membrane porin protein C
DNA Sequence 
>gi|24111450:2333031-2334152 Shigella flexneri 2a str. 301, complete genome
ATTAGAACTGGTAAACCAGACCCAGAGCTACGATGTTATCAGTGTTGATGCCAGCGTCACGAGTGAACTG
GTTGTCGTCCAGCAGGTTGATTTTGTAGTCAACGTAGGTGGACATGTTTTTGTTGAAGTAGTAGGTCGCA
CCAACATCAACATATTTCAGGATATCTTCGTCGTCGTAGTTACGACCATTGATGACACCCAGGTTTTTAC
CTTTAGACTGCAGGTAAGCCAGGGACGGACGCAGACCGAAGTCGAACTGGTACTGAGCAACAGCTTCGAA
GTTCTGTGCTTTGTTCGCCCAACCCAAGTTGCCTACGCGAGTTGCGTTGTAGGTCTGGGTGTACTGAGCA
GCTAGGTAGATGTTGTTCGCGTCGTATTTCAGACCACCGGTGTAGGTTTCAGCGCGGTCGCCATTACCGA
TGTAACGCTCATCATAACGGTTCAGACCGAAGTTCTGGTCATCAGTACGTTTGGAGCTGGAAACTGCAGC
ACCGATACCGAAGCCTTCGTAATCATAAGTAATAGAACCGCCAACGCCGTCACCGTTCTGACGCAGAGCT
TCACGACCGTTGTTGGTCATGCCTTCACCTTCCGGGCTACCGTTTTTGCCCTGATACTGAACAGCGAAGT
TCAGACCGTCAACCAGACCAAAGAAGTCGGTGCTACGGTAGGTTGCGAAGCCGTTACCACGCTGCTGCAT
GAAGTTGTCAGAACCGTAAGTGTCACCACCGAATTCTGGCAGTACGTCGGTCCAGGAAGTTACGTCGTAA
ACTACGCCGTAGTTACGACCGTAGTCGAAAGAACCTACATCCTGGAATTTCAGACCTGCGAATGCCACAC
GGGTCCAGGAGTTGTTTTCGTTTTCAGCGCTGTTGCCCTGGATCTGATATTCCCACTGGCCGTAACCGGT
CAGCTGGTCAGTAACCTGAGTTTCACCTTTGAAGCCAAGACGCATGTAGGTCTGGTCGCCATCTACAGAC
TTGTCGTCAGAGAAATAGTGCAGGCCGTCTACTTTACCGTACAGATCTAATTTGTTGCCGTCTTTGTTGT
AAACTTCAGCAGCGTTTGCTGCGCCTGCTACCAGCAGAGCTGGGACCAGGAGGGACAGTACTTTAACTTT
CA
Protein Sequence 
>gi|24113600|ref|NP_708110.1| porin [Shigella flexneri 2a str. 301] MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRSTDFFGLVDGLNFAVQYQGKNGSPEGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDDQNFGLNRYDERYIGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGVINGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ompC mutants were attenuated in their ability to spread cell to cell and kill epithelial cells, and had a negative Sereny test (Bernardini et al., 1993).
COG COG3203M, under M: Cell wall/membrane/envelope biogenesis
References
Bernardini et al., 1993: Bernardini ML, Sanna MG, Fontaine A, Sansonetti PJ. OmpC is involved in invasion of epithelial cells by Shigella flexneri. Infection and immunity. 1993; 61(9); 3625-3635. [PubMed: 8359885].