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iucA from Shigella flexneri 2a str. 301

Victor ID 879
Gene Name iucA from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1026161
NCBI Protein GI 56480400
Locus Tag SF3715
Protein Accession NP_709454.2
Other Database IDs UniProtKB-ID: Q9XCH4_SHIFL
UniRef100: UniRef100_Q31T55
UniRef90: UniRef90_Q47316
UniRef50: UniRef50_Q47316
UniParc: UPI00000B745B
EMBL: AF141323
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAD44746.1
EMBL-CDS: AAN45161.2
EMBL-CDS: AAP19034.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000087241.
EnsemblGenome_TRS: EBESCT00000088196
EnsemblGenome_PRO: EBESCP00000085018
EnsemblGenome: EBESCG00000089338.
EnsemblGenome_TRS: EBESCT00000090294
EnsemblGenome_PRO: EBESCP00000086930
Taxonomy ID 198214
Gene Starting Position 3820792
Gene Ending Position 3822573
Gene Strand (Orientation) +
Protein Name siderophore biosynthesis protein
DNA Sequence 
>gi|24111450:3820792-3822573 Shigella flexneri 2a str. 301, complete genome
AATGAGAATCATTATTGACATAATTGTTATTATTTTACTGTGTGGGAGCTGTTTGACTATGACCCTGCCC
TCTGAAAAACCAGCCACAGATGTGGCTGCGCAGTGCTTCCTGAATGCACTGATTCGTGAAACCACAGACT
GGAAACTGACAGAATACCCGCCAGACGAATTGCTCATCCCGCTGGATGAGCAGAAATCGCTCCATTTCAG
AGTGGCTTATTTCTCCCCAACCCAGCATCACCGCTTTGCATTTCCTGCACGTCTGGTCACGGCATCAGGC
AGTTATCCTGTCGACTTTACCACTCTCTCCCGGCTTATTATTGATAAGCTACGCCATCAACTGTTTCTGC
CCGTTCCCCTCTGCGAAACTTTCCACCAGCGCGTGCTGGAAAGCCATGTCCATACGCAACAGGCAATTGA
TGCCCGTCATGACTGGGCCGCTCTGCGTGAAAAAGCGTTGAATTTTGGCGAGGCTGAGCAGGCGCTGCTG
ACAGGACACGCTTTCCACCCTGCGCCTAAGTCTCATGAACCGTTTAACCGGCGGGAGGCTGAACGCTACC
TGCCTGATATGGCACCCCACTTCCCACTGCGGTGGTTTTCGGTGGATAAAACGCAAATCGCCGGTGAAAG
TTTGCATCTCAACCTTCAACAGCGGCTGACGCGATTTGCCGCAGAGAATGCGCCTCAGTTACTCAACGAA
TTAAGTGACAACCAATGGCTGTTCCCGTTGCACCCGTGGCAGGGGGAATATCTTTTGCAGCAGGGGTGGT
GCCAGGCACTTGTTGCTAAAGGGCTGATTAAAGACTTAGGTGAGGCCGGCACGTCGTGGCTGCCGACCAC
CTCTTCCCGTTCCCTCTACTGTGCCACCAGCCGCGATATGATCAAGTTCTCCCTGAGCGTACGGCTGACC
AACTCCATCCGTACTCTGTCCGTGAAAGAAGTGAAGCGTGGGATGCGCCTGGCACGCCTGGCTCAAACCG
ACGGCTGGCAGATGCTACAGGTCCGCTTCCCGACTTTCCGGGTAATGCAGGAGGATGGCTGGGCCGGGCT
GCTCGATCTTAACGGCAACATCATGCAGGAAAGTCTGTTTGCCCTGCGTGAAAATCTGCTGGTGGATCAG
CCGAAAAGCCAGACTAACGTACTGGTCTCCCTGACTCAGGCCGCACCTGATGGCGGTGATTCGCTGCTGG
TTTCGGCGGTAAAACGCCTGAGCGATCGCCTCGGTATCACTGTGCAACAGGCCGCCCATGCATGGGTTGA
TGCATACTGTCAGCAAGTGCTAAAGCCGCTGTTTACGGCTGAAGCGGATTACGGCCTGGTGCTGCTGGCG
CATCAGCAAAATATTCTTGTCCAGATGCTTGGGGATCTGCCGGTCGGATTTATTTACCGTGACTGTCAGG
GCAGCGCTTTTATGCCTCACGCGACAGACTGGCTCGATTCTATTGGCGAGGCGCAGGCGGAAAATATTTT
CACCCATGAGCAGTTGCTGCGCTATTTCCCTTATTACCTGCTGGTTAACTCCACTTTTGCTGTGACCGCT
GCGCTGGGGGCTGCCGGGCTGGACAGCGAATCGAATCTGATGGCTCGTGTACGAGCATCGCTGGCTGAAG
TGCGTGATCAGGTGACTCATAAAACCTGTCTCAACTACGTGCTGGAAAGTCCGTACTGGAACGTAAAAGG
TAACTTTTTCTGTTATCTGAACGATCATAACGAGAACACCATTGTTGACCCTTCGGTGATCTATTTCGAT
TTCGCTAACCCGCTGCAGGCTCAGGAGGTCTG
Protein Sequence 
>gi|56480400|ref|NP_709454.2| siderophore biosynthesis protein [Shigella flexneri 2a str. 301] MRIIIDIIVIILLCGSCLTMTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVAYFSPTQHHRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFNRREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iuc mutants are attenuated in chicken embryos and rabbit ileal loops (Wyckoff et al., 2009).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wyckoff et al., 2009: Wyckoff EE, Boulette ML, Payne SM. Genetics and environmental regulation of Shigella iron transport systems. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2009; 22(1); 43-51. [PubMed: 19130265].