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iucC from Shigella flexneri 2a str. 301

Victor ID 878
Gene Name iucC from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1026151
NCBI Protein GI 24114946
Locus Tag SF3717
Protein Accession NP_709456.1
Other Database IDs UniProtKB-ID: Q83PM4_SHIFL
UniRef100: UniRef100_B7MST1
UniRef90: UniRef90_Q47318
UniRef50: UniRef50_Q47318
UniParc: UPI000000E78F
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAN45163.1
EMBL-CDS: AAP19032.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000084758.
EnsemblGenome_TRS: EBESCT00000085713
EnsemblGenome_PRO: EBESCP00000082535
EnsemblGenome: EBESCG00000092097.
EnsemblGenome_TRS: EBESCT00000093053
EnsemblGenome_PRO: EBESCP00000089689
GenomeReviews: AE005674_GR
GenomeRev
Taxonomy ID 198214
Gene Starting Position 3823521
Gene Ending Position 3825263
Gene Strand (Orientation) +
Protein Name siderophore biosynthesis protein
DNA Sequence 
>gi|24111450:3823521-3825263 Shigella flexneri 2a str. 301, complete genome
AATGAATCACAAGGACTGGGATTTTGTTAACCGTCGGCTGGTGGCAAAAATGTTGTCTGAGATGGAGTAT
GAGCAGGTTTTCCACGCGGAATCTCAGGGCGATGACCACTACTGCATTAACCTGCCGGGAGCACAATGGC
GCTTCATCGCTGAACGTGGTATCTGGGGCTGGCTGTGGATTGATGCCCAAACGTTGCGCTGCACGGACGA
ACCAGTACTGGCGCAGACGCTGCTGATGCAGCTAAAGCCGGTGCTGTCAATGAGTGATGCCACTGTTGCA
GAGCATATGCAGGATTTGTATGCCACGCTACTGGGCGACCTGCAACTGCTGAAGGCCCGTCGCGGACTGA
GTGCCAGTGACCTGATTAATCTTGATGCCGATCGTCTGCAATGCCTGCTGAGCGGTCATCCTAAATTCGT
TTTTAATAAAGGTCGCCGTGGCTGGGGCAAAGAGGCGCTGGAACGATATGCGCCAGAGTATACCAACACC
TTCAGACTGCACTGGCTGGCGGTAAAACGTGAACATATGATCTGGCGCTGCGATAACGATCTGGATATTC
AGCAGTTGTTGACTGCCGCAATGGATCCGCAGGAGTTTACACGCTTCAGTCAGGTCTGGCAGGAAAACGG
GCTGGATCACAACTGGCTGCCGCTGCCGGTACATCCGTGGCAGTGGCAGCAAAAAATCGCCACAGACTTC
ATCGCTGATTTTGCCGAAGGCAGGATGGTGTCTCTCGGCGAGTTTGGCGACCAGTGGCTCGCCCAGCAGT
CGCTGCGTACCCTGACCAACGCCAGCCGCCGGGGAGGGCTGGATATCAAGCTGCCGCTGACCATCTACAA
TACCTCATGCTACCGGGGGATCCCTGGCAGATATATCGCTGCCGGACCACTGGCTTCACGCTGGCTGCAA
CAGGTTTTTGCGACCGACGCCACCCTGGTGCAAAGCGGCGCAGTGATCCTTGGTGAACCGGCTGCAGGCT
ATGTGTCCCATGAAGGCTATGCCGCGCTTGCCCGGGCTCCCTATCGCTACCAGGAAATGCTTGGTGTTAT
CTGGCGGGAGAATCCGTGCCGCTGGCTGAAACCGGATGAAAGTCCTGTTCTGATGGCAACACTGATGGAG
TGCGACGAAAACAATCAGCCGCTGGCAGGCGCATATATCGACCGCTCCGGACTGGACGCTGAAACCTGGC
TTACGCAATTGTTCCGGGTGGTTGTGGTTCCGCTGTATCACCTGCTTTGCCGCTACGGTGTCGCGCTTAT
TGCACACGGACAAAATATAACGCTCGCCATGAAAGAGGGGGTACCACAGCGTGTTCTGCTGAAAGACTTC
CAGGGCGATATGCGGCTGGTGAAAGAAGCGTTTCCCGAAATGGACTCTTTGCCTCAGGAGGTGCGTGATG
TCACATCCCGTCTGAGTGCGGACTACTTAATCCATGATTTGCAGACGGGTCACTTCGTGACAGTACTGCG
TTTTATTTCGCCACTGATGGTTCGTCTTGGCGTACCTGAAAGGCGATTTTATCAACTGCTGGCAGCAGTG
TTGAGTGATTACATGAACAAACATCCACAAATGGCAGAGCGTTTTGCGCTTTTCTCACTCTTCAGGCCAC
AAATCATTCGCGTGGTGCTGAACCCGGTAAAACTGACCTGGCCGGACCTGGATGGCGGCAGTCGCATGCT
GCCGAATTACCTTGAGAATCTGCAAAATCCGCTGTGGCTGGTAACTCAGGAATATGAATCATG
Protein Sequence 
>gi|24114946|ref|NP_709456.1| siderophore biosynthesis protein [Shigella flexneri 2a str. 301] MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGAQWRFIAERGIWGWLWIDAQTLRCTDEPVLAQTLLMQLKPVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYTNTFRLHWLAVKREHMIWRCDNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEAFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMNKHPQMAERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLENLQNPLWLVTQEYES
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iuc mutants are attenuated in chicken embryos and rabbit ileal loops (Wyckoff et al., 2009).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wyckoff et al., 2009: Wyckoff EE, Boulette ML, Payne SM. Genetics and environmental regulation of Shigella iron transport systems. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2009; 22(1); 43-51. [PubMed: 19130265].