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dksA from Shigella flexneri 2a str. 301

Victor ID 868
Gene Name dksA from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1024482
NCBI Protein GI 56479612
Locus Tag SF0137
Protein Accession NP_706093.2
Other Database IDs UniProtKB-ID: DKSA_SHIFL
UniRef100: UniRef100_P0ABS3
UniRef90: UniRef90_P0A1G6
UniRef50: UniRef50_Q89AR3
UniParc: UPI0000000B51
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAN41800.1
EMBL-CDS: AAP15681.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000084459
EnsemblGenome_TRS: EBESCT00000085414
EnsemblGenome_PRO: EBESCP00000082236
EnsemblGenome: EBESCG00000092360
EnsemblGenome_TRS: EBESCT00000093316
EnsemblGenome_PRO: EBESCP00000089952
GenomeReviews: AE005674_GR
GenomeReviews
Taxonomy ID 198214
Gene Starting Position 151926
Gene Ending Position 152381
Gene Strand (Orientation) -
Protein Name DnaK transcriptional regulator DksA
DNA Sequence 
>gi|24111450:151926-152381 Shigella flexneri 2a str. 301, complete genome
ATTAGCCAGCCATCTGTTTTTCGCGAATTTCAGCCAGCGTTTTGCAGTCGATGCACAGATCGGCTGTCGG
GCGCGCTTCCAGACGGCGAATACCAATTTCAACACCGCAGGATTCGCAGTAGCCGAAATCTTCGTCTTCC
ACTTTTTTCAGCGTCTTCTCGATCTTTTTGATCAGCTTACGCTCGCGATCGCGGTTACGCAGTTCGAGGC
TGAACTCTTCTTCCTGGGCTGCACGGTCTACCGGGTCCGGGAAGTTGGCTGCTTCATCCTGCATATGTGT
AACGGTGCGATCGACTTCATCCCTGAGTTGATTACGCCATGCTTCCAGAATACGACGGAAGTGCGCCAGC
TGGGCTTCATTCATATACTCTTCGCCCGGCTTCTCCTGATATGGTTCCACCCCAGCGATGGCGAGAATAC
TCAGGGACGATGTTTTACGGTTTTGCCCTTCTTGCA
Protein Sequence 
>gi|56479612|ref|NP_706093.2| RNA polymerase-binding transcription factor [Shigella flexneri 2a str. 301] MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRILEAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dksA mutants are able to invade cultured cell monlayers but are incapable of cell to cell spread (Mogull et al., 2001).
COG COG1734T, under T: Signal transduction mechanisms
References
Mogull et al., 2001: Mogull SA, Runyen-Janecky LJ, Hong M, Payne SM. dksA is required for intercellular spread of Shigella flexneri via an RpoS-independent mechanism. Infection and immunity. 2001; 69(9); 5742-5751. [PubMed: 11500451].