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galU from Shigella flexneri 2a str. 301

Victor ID 864
Gene Name galU from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1024213
NCBI Protein GI 24112632
Locus Tag SF1236
Protein Accession NP_707142.1
Other Database IDs UniProtKB-ID: GALU_SHIFL
UniRef100: UniRef100_P0AEP5
UniRef90: UniRef90_P0AEP5
UniRef50: UniRef50_Q05026
UniParc: UPI00001639AF
EMBL: L32811
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAD15244.1
EMBL-CDS: AAN42849.1
EMBL-CDS: AAP16734.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000086741
EnsemblGenome_TRS: EBESCT00000087696
EnsemblGenome_PRO: EBESCP00000084518
EnsemblGenome: EBESCG00000090736
EnsemblGenome_TRS: EBESCT00000091692
EnsemblGenome_PRO: EBESCP00000088328
Genome
Taxonomy ID 198214
Gene Starting Position 1286495
Gene Ending Position 1287403
Gene Strand (Orientation) +
Protein Name UTP--glucose-1-phosphate uridylyltransferase subunit GalU
DNA Sequence 
>gi|24111450:1286495-1287403 Shigella flexneri 2a str. 301, complete genome
AATGGCTGCCATTAATACGAAAGTCAAAAAAGCCGTTATCCCCGTTGCGGGATTAGGAACCAGGATGTTG
CCGGCGACGAAAGCCATCCCGAAAGAGATGCTGCCACTTGTCGATAAGCCATTAATTCAATACGTCGTGA
ATGAATGTATTGCGGCTGGCATTACTGAAATTGTGCTGGTTACACACTCATCTAAAAACTCTATTGAAAA
CCACTTTGATACCAGTTTTGAACTGGAAGCAATGCTGGAAAAACGTGTAAAACGTCAACTGCTTGATGAA
GTGCAGTCTATTTGTCCACCGCACGTGACTATTATGCAAGTTCGTCAGGGTCTGGCGAAAGGCCTGGGAC
ACGCGGTATTGTGTGCTCACCCGGTAGTGGGTGATGAACCGGTAGCTGTTATTTTGCCTGATGTTATTCT
GGATGAATATGAATCCGATTTGTCACAGGATAACCTGGCAGAGATGATCCGCCGCTTTGATGAAACGGGT
CATAGCCAGATCATGGTTGAACCGGTTGCTGATGTGACCGCATATGGCGTTGTGGATTGCAAAGGCGTTG
AATTAGCGCCGGGTGAAAGCGTACCGATGGTTGGTGTGGTAGAAAAACCGAAAGCGGATGTTGCGCCGTC
TAATCTCGCTATTGTGGGTCGTTACGTACTTAGCGCGGATATTTGGCCGTTGCTGGCAAAAACCCCTCCG
GGAGCTGGTGATGAAATTCAGCTCACCGACGCAATTGATATGCTGATCGAAAAAGAAACGGTGGAAGCCT
ATCATATGAAAGGGAAGAGCCATGACTGCGGTAATAAATTAGGTTACATGCAGGCCTTCGTTGAATACGG
TATTCGTCATAACACCCTTGGCACGGAATTTAAAGCCTGGCTTGAAGAAGAGATGGGCATTAAGAAGTA
Protein Sequence 
>gi|24112632|ref|NP_707142.1| UTP-glucose-1-phosphate uridylyltransferase [Shigella flexneri 2a str. 301] MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFDETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRYVLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHNTLGTEFKAWLEEEMGIKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: galU mutant is attenuated in cell to cell spread in He La cells (Sandlin et al., 1995).
COG COG1210M, under M: Cell wall/membrane/envelope biogenesis
References
Sandlin et al., 1995: Sandlin RC, Lampel KA, Keasler SP, Goldberg MB, Stolzer AL, Maurelli AT. Avirulence of rough mutants of Shigella flexneri: requirement of O antigen for correct unipolar localization of IcsA in the bacterial outer membrane. Infection and immunity. 1995; 63(1); 229-237. [PubMed: 7528731].