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aroA from Shigella flexneri 2a str. 301

Victor ID 861
Gene Name aroA from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1023875
NCBI Protein GI 24112316
Locus Tag SF0903
Protein Accession NP_706826.1
Other Database IDs UniProtKB-ID: AROA_SHIFL
UniRef100: UniRef100_Q0SX08
UniRef90: UniRef90_A8AIH5
UniRef50: UniRef50_B1JXR9
UniParc: UPI000000E04D
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAN42533.1
EMBL-CDS: AAP16419.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
HSSP: P0A6D3
EnsemblGenome: EBESCG00000087660
EnsemblGenome_TRS: EBESCT00000088616
EnsemblGenome_PRO: EBESCP00000085438
EnsemblGenome: EBESCG00000090594
EnsemblGenome_TRS: EBESCT00000091550
EnsemblGenome_PRO: EBESCP00000088186
GenomeReviews: AE005674_GR
Taxonomy ID 198214
Gene Starting Position 941163
Gene Ending Position 942446
Gene Strand (Orientation) +
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
DNA Sequence 
>gi|24111450:941163-942446 Shigella flexneri 2a str. 301, complete genome
CATGGAATCCCTGACGTTACAACCCATCGCTCGTGTCGATGGCACTATTAATCTGCCCGGTTCCAAGAGC
GTTTCTAACCGCGCTTTATTGCTTGCGGCATTAGCACACGGCAAAACAGTATTAACCAATCTGCTGGATA
GCGACGACGTGCGCCATATGCTGAATGCATTAACAGCGTTAGGGTTAAGCTATACGCTTTCAGCCGATCG
TACGCGTTGCGAAATTATCGGTAACGGCGGTCCATTACACGCAGAAGGTGCCCTGGAGTTGTTCCTCGGT
AACGCCGGAACGGCAATGCGTCCGCTGGCGGCAGCTCTTTGTCTGGATAGCAATGATATTGTGCTGACCG
GTGAGCCGCGTATGAAAGAGCGCCCGATTGGTCATCTGGTGGATGCGCTGCGCCTGGGCGGGGCGAAGAT
CACTTACCTGGAACAAGAAAATTATCCGCCGTTGCGTTTACAGGGCGGCTTTACTGGCGGCAACGTTGAC
GTTGATGGCTCCGTTTCCAGCCAATTCCTCACCGCACTGTTAATGACTGCGCCTCTTGCGCCGGAAGATA
CGGTGATTCGTATTAAAGGCGATCTGGTTTCTAAACCTTATATCGACATCACACTCAATCTGATGAAGAC
GTTTGGTGTTGAAATTGAAAATCAGCACTATCAACAATTTGTCGTAAAAGGCGGGCAGTCTTATCAGTCT
CCGGGTACTTATTTGGTCGAAGGCGATGCATCTTCGGCTTCTTACTTCCTGGCAGCAGCAGCAATCAAAG
GCGGCACTGTAAAAGTGACCGGTATTGGACGTAACAGTATGCAGGGTGATATTCGCTTTGCTGATGTGCT
GGAAAAAATGGGCGCGACCATTTGCTGGGGCGATGATTATATTTCCTGCACGCGTGGTGAACTGAACGCT
ATTGATATGGATATGAACCATATTCCTGATGCGGCGATGACCATTGCCACGGCGGCGTTATTTGCAAAAG
GCACCACCACGCTGCGCAATATCTATAACTGGCGTGTTAAAGAGACCGATCGCCTGTTTGCGATGGCAAC
AGAACTGCGTAAAGTCGGCGCGGAAGTGGAAGAGGGGCACGATTACATTCGTATCACTCCTCCGGAAAAA
CTGAACTTTGCCGAGATCGCGACATACAATGATCACCGGATGGCGATGTGTTTCTCGCTGGTGGCGTTGT
CAGATACACCAGTGACGATTCTTGATCCCAAATGCACGGCCAAAACATTTCCGGATTATTTCGAGCAGCT
GGCGCGGATTAGCCAGGCAGCCTG
Protein Sequence 
>gi|24112316|ref|NP_706826.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Shigella flexneri 2a str. 301] MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGLSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLDSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroA deletion mutants are attenuated in HeLa cells (Noriega et al., 1996).
COG COG0128E, under E: Amino acid transport and metabolism
References
Noriega et al., 1996: Noriega FR, Losonsky G, Lauderbaugh C, Liao FM, Wang JY, Levine MM. Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infection and immunity. 1996; 64(8); 3055-3061. [PubMed: 8757833].