Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

dsbA from Shigella flexneri 2a str. 301

Victor ID 860
Gene Name dsbA from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1023438
NCBI Protein GI 24115149
Locus Tag SF3931
Protein Accession NP_709659.1
Other Database IDs UniProtKB-ID: DSBA_SHIFL
UniRef100: UniRef100_P52235
UniRef90: UniRef90_P0A4L6
UniRef50: UniRef50_P0A4L6
UniParc: UPI00001298C2
EMBL: D38253
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: BAA07407.1
EMBL-CDS: AAN45366.1
EMBL-CDS: AAP18832.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
PDB: 3DKS
EnsemblGenome: EBESCG00000085117
EnsemblGenome_TRS: EBESCT00000086072
EnsemblGenome_PRO: EBESCP00000082894
EnsemblGenome: EBESCG00000091028
EnsemblGenome_TRS: EBESCT00000091984
EnsemblGenome_PRO: EBESCP00000088
Taxonomy ID 198214
Gene Starting Position 4056105
Gene Ending Position 4056731
Gene Strand (Orientation) +
Protein Name periplasmic protein disulfide isomerase I
DNA Sequence 
>gi|24111450:4056105-4056731 Shigella flexneri 2a str. 301, complete genome
CATGAAAAAGATTTGGCTGGCGCTGGCTGGTTTAGTTTTAGCGTTTAGCGCATCGGCGGCGCAGTATGAA
GATGGTAAACAGTACACTACCCTGGAAAAACCGGTAGCTGGCGCGCCGCAAGTGCTGGAGTTTTTCTCTT
TCTTCTGCCCGCACTGCTATCAGTTTGAAGAAGTTCTGCATATTTCTGATAATGTGAAGAAAAAACTGCC
GGAAGGCGTGAAGATGACTAAATACCACGTCAACTTCATGGGTGGTGACCTGGGCAAAGATCTGACTCAG
GCATGGGCTGTGGCGATGGCGCTGGGCGTGGAAGACAAAGTGACTGTTCCGCTGTTTGAAGGCGTACAGA
AAACCCAGACCATTCGTTCAGCATCTGATATCCGCGATGTATTTATCAATGCAGGTATTAAAGGTGAAGA
GTACGACGCGGCGTGGAACAGCTTCGTGGTGAAATCTCTGGTCGCTCAGCAGGAAAAAGCCGCAGCTGAT
GTGCAATTGCGTGGTGTTCCGGCGATGTTTGTTAACGGTAAATATCAGCTGAATCCGCAGGGTATGGATA
CCAGCAATATGGATGTTTTTGTTCAGCAGTATGCTGATACGGTGAAATATCTGTCCGAGGAAAAATA
Protein Sequence 
>gi|24115149|ref|NP_709659.1| periplasmic protein disulfide isomerase I [Shigella flexneri 2a str. 301] MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEEK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dsbA mutants are less invasive to MK-2 cell monolayers compared to the wild-type (Watarai et al., 1995).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Watarai et al., 1995: Watarai M, Tobe T, Yoshikawa M, Sasakawa C. Disulfide oxidoreductase activity of Shigella flexneri is required for release of Ipa proteins and invasion of epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1995; 92(11); 4927-4931. [PubMed: 7761426].