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plc from Clostridium perfringens str. 13

Victor ID 852
Gene Name plc from Clostridium perfringens str. 13
Sequence Strain (Species/Organism) Clostridium perfringens str. 13
NCBI Gene ID 988262
NCBI Protein GI 18309018
Locus Tag CPE0036
Protein Accession NP_560952.1
Other Database IDs UniProtKB-ID: PHLC1_CLOPE
UniRef100: UniRef100_P0C216
UniRef90: UniRef90_Q0TV31
UniRef50: UniRef50_Q0TV31
UniParc: UPI0000131BCB
EMBL: X17300
EMBL: D10248
EMBL: D32123
EMBL: D32124
EMBL: D32126
EMBL: D32127
EMBL: D32128
EMBL: D49968
EMBL: D49969
EMBL: L43545
EMBL: L43546
EMBL: L43547
EMBL: L43548
EMBL: D63911
EMBL: BA000016
EMBL-CDS: CAA35186.1
EMBL-CDS: BAA01093.1
EMBL-CDS: BAA06849.1
EMBL-CDS: BAA06850.1
EMBL-CDS: BAA06852.1
EMBL-CDS: BAA06853.1
EMBL-CDS: BAA06854.1
EMBL-CDS: BAA08720.1
EMBL-C
Taxonomy ID 195102
Gene Starting Position 48589
Gene Ending Position 49785
Gene Strand (Orientation) +
Protein Name phospholipase C
DNA Sequence 
>gi|18308982:48589-49785 Clostridium perfringens str. 13, complete genome
AATGAAAAGAAAGATTTGTAAGGCGCTTATTTGTGCTACGCTAGCAACTAGCCTATGGGCTGGGGCATCA
ACTAAAGTCTACGCTTGGGATGGAAAGATTGATGGAACAGGAACTCATGCTATGATTGTAACTCAAGGGG
TTTCAATCTTAGAAAATGATCTGTCCAAAAATGAACCAGAAAGTGTAAGAAAAAACTTAGAGATTTTAAA
AGAGAACATGCATGAGCTTCAATTAGGTTCTACTTATCCAGATTATGATAAGAATGCATATGATCTATAT
CAAGATCATTTCTGGGATCCTGATACAGATAATAATTTCTCAAAGGATAATAGTTGGTATTTAGCTTATT
CTATACCTGACACAGGGGAATCACAAATAAGAAAATTTTCAGCATTAGCTAGATATGAATGGCAAAGAGG
AAACTATAAACAAGCTACATTCTATCTTGGAGAGGCTATGCACTATTTTGGAGATATAGATACTCCATAT
CATCCTGCTAATGTTACTGCCGTTGATAGCGCAGGACATGTTAAGTTTGAAACTTTTGCAGAGGAAAGAA
AAGAACAGTATAAAATAAACACAGCAGGTTGCAAAACTAATGAGGATTTTTATGCTGATATCTTAAAAAA
CAAGGATTTTAATGCATGGTCAAAAGAATATGCAAGAGGTTTTGCTAAAACAGGAAAATCAATATACTAT
AGTCATGCTAGCATGAGTCATAGTTGGGATGATTGGGATTATGCAGCAAAGGTAACTTTAGCTAACTCTC
AAAAAGGAACAGCAGGATATATTTATAGATTCTTACACGATGTATCAGAGGGTAATGATCCATCAGTTGG
AAAGAATGTAAAAGAACTAGTAGCTTACATATCAACTAGTGGTGAAAAAGATGCTGGAACAGATGACTAC
ATGTATTTTGGAATCAAAACAAAGGATGGAAAAACTCAAGAATGGGAAATGGACAACCCAGGAAATGATT
TTATGACTGGAAGTAAAGACACTTATACTTTCAAATTAAAAGATGAAAATCTAAAAATTGATGATATACA
AAATATGTGGATTAGAAAAAGAAAATATACAGCATTCCCAGATGCTTATAAGCCAGAAAACATAAAGATA
ATAGCAAATGGAAAAGTTGTAGTAGACAAAGATATAAATGAGTGGATTTCAGGAAATTCAACTTATAATA
TAAAATA
Protein Sequence 
>gi|18309018|ref|NP_560952.1| phospholipase C [Clostridium perfringens str. 13] MKRKICKALICATLATSLWAGASTKVYAWDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: plc mutant is attenuated in mice (Awad et al., 1995).
References
Awad et al., 1995: Awad MM, Bryant AE, Stevens DL, Rood JI. Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene. Molecular microbiology. 1995; 15(2); 191-202. [PubMed: 7746141].