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Cj1349c

Victor ID 839
Gene Name Cj1349c
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 905641
NCBI Protein GI 218562958
Locus Tag Cj1349c
Genbank Accession AL111168
Protein Accession YP_002344737
Other Database IDs UniProtKB-ID: Q0P8R0_CAMJE
UniRef100: UniRef100_A3YLR3
UniRef90: UniRef90_A1W0W5
UniRef50: UniRef50_A8FN27
UniParc: UPI00000C1ED4
EMBL: AL111168
EMBL-CDS: CAL35461.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj1349c
HOGENOM: HBG500051
OMA: TSIYESK
ProtClustDB: CLSK872578
BioCyc: CJEJ192222:CJ1349C-MONOMER
Taxonomy ID 192222
Gene Starting Position 1280991
Gene Ending Position 1282298
Gene Strand (Orientation) -
Protein Name putative fibronectin/fibrinogen-binding protein
Protein pI 9.92
Protein Weight 49598.68
Protein Length 435
Protein Note Original (2000) note: Cj1349c, possible fibronectin/fibrinogen-binding protein, len: aa; similar to TR:Q54858 (EMBL: L28919) Streptococcus pyogenes fibronectin/fibrinogen-binding protein FBP54 (474 aa),fasta scores; opt: 213 z-score: 230.0 E(): 1.7e-05, 23.2% identity in 466 aa overlap. 30.6% identity to HP1392~Updated (2006) note: Pfam domain PF05670 Domain of unknown function (DUF814) identified within CDS. No specific characterisation with acceptable identity score carried out yet, so putative kept within product function. Functional classification - Pathogenicity
DNA Sequence 
>gi|15791399:1280991-1282298 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
TTTAATCCTTTGTGATATTAATACTTTTAAAATTTGTATAATTTACAAACGCCTTTTGCTGAACCTTAAC
AAAATTTTTTAAAGTATAATCGACCCAATACGAACCTTTCTTTAACTTAGAAAAGCTTACACAAAGCCTT
GCAGCAAATTCTATCACATCGAGGCTGATTTTTTGCTTGTTTGATACAATCAAAGTATGTGCGCTAGGAA
TATCCCTTACATGAAGCCACAAATCATCTTTTTTAGCATTTTTAAGTAAAAATTCATTGCCTTTTTCATT
TTTACCCACGCAAATTTTAAACTCGTTAAAATAAAAATTTGCGACAAGATCTTCTTGTTTATGATCTTGA
TTTTTTTTGCTATTTTTTTTAGGTAGTAAAATTTCAAGCTCTATCTCACTCTTAGCTTGAAGCAATAATT
CTTTCAAACTCAAGGTAAAATCTAACTTTTCTTTTAAATTTTGTCTTTGTATGTTTAAATTTTTAGCTTT
TTGTTCTAATTTTTTAGCATTTTTATAATATAAATTAGCGCTTTGCTTAGGATTAAATTCAAGCTTAAAT
TCAAGCTCTTTGCCTTCAAAATCATCAAGCTTAAATTCCCTTTCATAATCTTTTAAAACACTCAAATTTG
CAAACAATACATCAGCCCTTTTTCTGTATTCTAAAGCTTTTAAGAGTAAAGAATTTTCTTCATCTAAACT
AGAAAAAAGTTCTTGTAAATTTTGTATTTTTTTATCCACTTGTGCAAGTTTTAAATTTTTTATTTGTTTG
ATTTTACTCTCATAAATGCTTGTAAATTTGCGAGAAAAATAATCTGCAAAGTCTTTAATTTCCTCAAAAT
TTTCATCCATTTTATAAGGCTTTAAAGACTCTAAAATCACATTAGGTTTTACAACACGATAACTTTTATC
AATGTGTCTTAAAGCCTCTATGATCAAATCTTTTTCATCTGTAAGAATAACATTGGTATTTTTACCCGTA
AATTCAAAATAAATTTTGCTCTCATAGCTTTTATAAGCCTTATTAGCTTTTACACTAAAACATAAAATAC
GATTGCCTTCAAGGACTTTAACTTCCTTTATAAAAGCATTGCTAAAATACTTTTTAAGCATAAAATCAAA
AGGTGCATTATAATTTTTTGCATTAAATTTAGCTGTATAAATCGCACTCATTGCACGAGTAAGATCAAAA
ATAAATCTTTCTCTATCAAAGCTTAATTCCAAAATATTGTCATTGATACGCTTGATAAAATCAATTTTTT
TAAACCGAGAAAAAAAAGTTTGTAATTGTAAAAGTTCTGTGTATTTCA
Protein Sequence 
>gi|218562958|ref|YP_002344737.1| putative fibronectin/fibrinogen-binding protein [Campylobacter jejuni subsp. jejuni NCTC 11168]
MKYTELLQLQTFFSRFKKIDFIKRINDNILELSFDRERFIFDLTRAMSAIYTAKFNAKNYNAPFDFMLKK
YFSNAFIKEVKVLEGNRILCFSVKANKAYKSYESKIYFEFTGKNTNVILTDEKDLIIEALRHIDKSYRVV
KPNVILESLKPYKMDENFEEIKDFADYFSRKFTSIYESKIKQIKNLKLAQVDKKIQNLQELFSSLDEENS
LLLKALEYRKRADVLFANLSVLKDYEREFKLDDFEGKELEFKLEFNPKQSANLYYKNAKKLEQKAKNLNI
QRQNLKEKLDFTLSLKELLLQAKSEIELEILLPKKNSKKNQDHKQEDLVANFYFNEFKICVGKNEKGNEF
LLKNAKKDDLWLHVRDIPSAHTLIVSNKQKISLDVIEFAARLCVSFSKLKKGSYWVDYTLKNFVKVQQKA
FVNYTNFKSINITKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Cj1349c mutants had a significantly reduced ability to colonize chicken epithelial cells (Flanagan et al., 2009)
References
Flanagan et al., 2009: Flanagan RC, Neal-McKinney JM, Dhillon AS, Miller WG, Konkel ME. Examination of Campylobacter jejuni putative adhesins leads to the identification of a new protein, designated FlpA, required for chicken colonization. Infection and immunity. 2009; 77(6); 2399-2407. [PubMed: 19349427].