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flaA

Victor ID 838
Gene Name flaA
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 905631
NCBI Protein GI 218562948
Locus Tag Cj1339c
Genbank Accession AL111168
Protein Accession YP_002344727
Other Database IDs UniProtKB-ID: FLA1_CAMJE
UniRef100: UniRef100_P56963
UniRef90: UniRef90_P56963
UniRef50: UniRef50_P22251
UniParc: UPI00001684E0
EMBL: AL111168
EMBL-CDS: CAL35451.1
RefSeq_NT: NC_002163.1
MINT: MINT-6485335
GenomeReviews: AL111168_GR
KEGG: cje:Cj1339c
HOGENOM: HBG758847
OMA: TATITHN
ProtClustDB: PRK08411
BioCyc: CJEJ192222:CJ1339C-MONOMER
Taxonomy ID 192222
Gene Starting Position 1269231
Gene Ending Position 1270949
Gene Strand (Orientation) -
Protein Name flagellin
Protein pI 5.36
Protein Weight 55763.1
Protein Length 572
Protein Note FlaA; structural flagella protein; in Helicobacter the flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions
DNA Sequence 
>gi|15791399:1269231-1270949 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
ACTACTGTAGTAATCTTAAAACATTTTGTTGAACAGAATTAGCCTGTGCCATGGCATAAGAGCCGCTTTG
AGCTAAGATATTTGCTTTAGAGTAGTTTGCACTCTCGGCTGCAAAGTCTACATCACGGATTTGCGATTCT
GCTGCTTTAACGTTTACTTGAGTTACGGTGATGTTGTTTATAGTTGATGTAACTTGATTTTGTACCGAAC
CAATGTCGGCTCTGATTTGATCAAGATTTGTTATAGCTGTTTCAGCTATATCCATCACAGCCATAGCGCC
TTTAAGTGTGGTAACACCTGCTGTTTCATCTTTTACTCCAAAAGCAGTTGTTTTCATAGTTGCAAACTGA
GAAAGTGTTGAACCACTTGAAAAACCTGAGCCTGCAGAAACATTATATACCGTAGAAAGTTGCGAAGCAG
CTGAAATAGCTATAGCGTTTGCAAAACCTGTGGAATAATTTTTACCGCTACCTACAGAATAACCTGAACC
TGAAGAAAATCCACTTCCTGCGCTACTCATATAGGCACTAACAGAAGAATAACCACCTAACACAACTCCT
TTGTTTGCAGAACCAAATCCCATAGCATCAGCGATATTAGCATCAATTTGTCCTTTTGACTCTCTTAAAG
AAACAGAAGCTTGAGAGATAAATTGAGTTGCACCAAAACCTGCAGAAGAAAGATTGCTACCGCTGATTAA
AATATCTTTACCATCATTTTTAACTAAAGACAAGCGGCCATAGTTTTCTTTCATATCAGCATTGATAAAG
GCACCTCCACCTATATTACCATCGATTTTAATCCCTCTACCTTCTCTTGAAGTAAGTAAAAGTTGTCCAT
TAGCATCGATCGAAGCTTCAACTCCAGTGGTATCTTTAACCGAATTGATTGCAGCAACTAAGGCTCCATT
AGCATCACCATCTTTGTAATCTACTTTACCGATTTTTACCCCATTGATAGCAAAAGTATCTGAAGTAGCT
CCTGCTCTAACTGCAGCTATACCTCTAGTTTCTACTGTAAAAGTAGCTCTAACACCTGTTTTATCAGCAT
TTTTATTGATCTCATCTGCTAAAGCTCCAAGTCCTGTTCCAACTGAAGTTGAAATCACAACTTTTTGAAA
CTGAAAATCATCTATACCATTGTAATTTTTAAGAGTAAATTGTACTTCGCCACTAGTTGAAATTCTTCCT
CCTGTTTCAAAGCGTGTTAAACCTATCTTAGAAGATTGAGTTGCTCCTATAGTAGCTTTTACAGTTTGAT
TTGAACTTGCACCGATTTGAAATTCTTGATTGATAAAATTCCCACTTAAAAGTTGTTTACCGTTAAATGA
AGTAGTATTTGCAATATTGTCAAGTTCTTCCATTAAACGGTTGATATCTGCTTGAAGCATGGTTCTTGTT
TTTAAACTTTGTCCATCTTGAGCCGCTTGAGTTGCCTTAGTTTTGATTGTATCTAAGATTTTAAGTTGCT
CATCCATAGCCTTATCAGCAGTTTGTAAGATACCTAAAGCATCATTACCATTAGATATAGCTTGACCTAA
AGTATTAGCTTGAGATCTTAAACTATCTGCTATCGCCATCCCTGAAGCATCATCTGCTGCGGAGTTGATT
CTAAGACCTGAACTAAGTCTGCTTAAAGAAGCATCTAAACTTTTACTATTTAAATCAGCGTTTGCTTTTG
CATTTAAAGCTGCAACATTGGTGTTAATACGAAATCCCA
Protein Sequence 
>gi|218562948|ref|YP_002344727.1| flagellin [Campylobacter jejuni subsp. jejuni NCTC 11168]
MGFRINTNVAALNAKANADLNSKSLDASLSRLSSGLRINSAADDASGMAIADSLRSQANTLGQAISNGND
ALGILQTADKAMDEQLKILDTIKTKATQAAQDGQSLKTRTMLQADINRLMEELDNIANTTSFNGKQLLSG
NFINQEFQIGASSNQTVKATIGATQSSKIGLTRFETGGRISTSGEVQFTLKNYNGIDDFQFQKVVISTSV
GTGLGALADEINKNADKTGVRATFTVETRGIAAVRAGATSDTFAINGVKIGKVDYKDGDANGALVAAINS
VKDTTGVEASIDANGQLLLTSREGRGIKIDGNIGGGAFINADMKENYGRLSLVKNDGKDILISGSNLSSA
GFGATQFISQASVSLRESKGQIDANIADAMGFGSANKGVVLGGYSSVSAYMSSAGSGFSSGSGYSVGSGK
NYSTGFANAIAISAASQLSTVYNVSAGSGFSSGSTLSQFATMKTTAFGVKDETAGVTTLKGAMAVMDIAE
TAITNLDQIRADIGSVQNQVTSTINNITVTQVNVKAAESQIRDVDFAAESANYSKANILAQSGSYAMAQA
NSVQQNVLRLLQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: nonflagellated, nonmotile (flaA flaB Mot-) mutants of C. jejuni had a 30%-40% decrease in INT 407 cell internalization (Grant et al., 1993)
References
Grant et al., 1993: Grant CC, Konkel ME, Cieplak W Jr, Tompkins LS. Role of flagella in adherence, internalization, and translocation of Campylobacter jejuni in nonpolarized and polarized epithelial cell cultures. Infection and immunity. 1993; 61(5); 1764-1771. [PubMed: 8478066].