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Cj1324 |
| Victor ID |
834 |
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Gene Name |
Cj1324 |
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Sequence Strain (Species/Organism) |
Campylobacter jejuni subsp. jejuni NCTC 11168 |
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NCBI Gene ID |
905616
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NCBI Protein GI |
218562935
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Locus Tag |
Cj1324 |
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Genbank Accession |
AL111168 |
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Protein Accession |
YP_002344714 |
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Other Database IDs |
UniProtKB-ID: Q0P8T3_CAMJE
UniRef100: UniRef100_E0QBH8
UniRef90: UniRef90_E0QBH8
UniRef50: UniRef50_E0QBH8
UniParc: UPI00000C1EC0
EMBL: AL111168
EMBL-CDS: CAL35438.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj1324
HOGENOM: HBG740439
OMA: LHTYLMY
ProtClustDB: CLSK2410374
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Taxonomy ID |
192222
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Gene Starting Position |
1252277 |
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Gene Ending Position |
1253398 |
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Gene Strand (Orientation) |
+ |
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Protein Name |
hypothetical protein |
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Protein pI |
7.86 |
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Protein Weight |
42137.92 |
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Protein Length |
373 |
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Protein Note |
Original (2000) note: Cj1324, unknown, len: 373 aa; some similarity to TR:P72140 (EMBL: U50396) Pseudomonas aeruginosa WBPG (lipopolysaccharide gene cluster) (376 aa), fasta scores; opt: 166 z-score: 199.7 E(): 0.0008,20.1% identity in 378 aa overlap. No Hp match. Also similar to Cj1316c~Updated (2006) note: Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Literature search identified paper linking Cj1321-Cj1326 as being a glycosylation islet (Champion et al., 2005). Also shows some similarity to Cj1316 pseudaminic acid biosynthesis PseA protein. Functional classification - Surface polysaccharides,lipopolysaccharides and antigens~PMID:16230626, PMID:16573682, PMID:12781527 |
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DNA Sequence |
>gi|15791399:1252277-1253398 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
AATGATTTATTGTGATCACTGCGTGATGCCAAATACTAGACCTGGTATTAATTTTACAAAAGATAAAGAA
GGTAAAAATATCTGTTCAGCTTGCATCAATCATAAAAATAAAGAAAATATTGATTATAAAGCAAGGTTTA
AAGAGCTTGAAGTCTTATGCGATAAATACCGCAGAATGAATGGAAAATTTGAATATGATTGTGCTATTGC
CGTAAGTGGAGGTAAAGATTCGCATTTTCAAGTGCATATCATGAAAGAAAAACTTGGAATGAATCCTATT
CTTTTTAGCGTTGAAGATAATTTCACCATGACTGAAGCAGGCAAGAAAAATCTTAAAAATTTAAGTGAAA
CTTTTGGTTGTCATATCATTAGCTTAAAGCCTGATATCAAAACTCAAAAAAAAGTTATGCTAAAAACCTT
TGAAAAATATGGAAAACCTACTTGGTTTATTGATAGACTAATTTACAGCTATCCTTTTGCTATGGCTTTA
AAATTTAATACACCTTTATTGGTTTATGGAGAAAATGTTAGTTATGAATATGGAGGTAGTGATACCGAAG
AAACTCCTAGCGCTAAAGAAATATTTTTAAATGGTGTAGCTAGTGATTTAAATATAAATGAATTTATAGA
TGATGAAATCAAAGAAGAAAATTTGCAACTCTTTTTCAATCCAAACAAAGATAAACTCGATAAACTTAAC
CCTATCTATCTAAGTTATTTTGTAAAATGGAATTCTTATAGCAATTATATTTTTGCTAAAAGTCGTGGTT
TTACTGATCTAGAAGGCGAATGGGATAGAACAATGTGTGCAGAAAATTTTGATCAAGTTGATAGTATAGG
CTATATCCTACACGCTTGGATGAAATACCCTAAATTTGGTCATGCTTGTGCGAGTGATTACGCAGCTCGT
TTCGTGCGTTATGGACTTTTAAGCAGAAAAGAAGCTATTGAACTTGTGCAAAAAAGAGATCATAAGCTTG
ACAATAAATGCGTTGAAGATTTTTGCAATTTCATAGGTATTAGTAAAACTACATTTTGGAAAATAGTAGA
AAAACATTACAATATGGATTTATTTTATAAAAATGATTTTGGAGAATTTAAATTAAAAAACAAATTACAA
TA
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Protein Sequence |
>gi|218562935|ref|YP_002344714.1| hypothetical protein Cj1324 [Campylobacter jejuni subsp. jejuni NCTC 11168]
MIYCDHCVMPNTRPGINFTKDKEGKNICSACINHKNKENIDYKARFKELEVLCDKYRRMNGKFEYDCAIA
VSGGKDSHFQVHIMKEKLGMNPILFSVEDNFTMTEAGKKNLKNLSETFGCHIISLKPDIKTQKKVMLKTF
EKYGKPTWFIDRLIYSYPFAMALKFNTPLLVYGENVSYEYGGSDTEETPSAKEIFLNGVASDLNINEFID
DEIKEENLQLFFNPNKDKLDKLNPIYLSYFVKWNSYSNYIFAKSRGFTDLEGEWDRTMCAENFDQVDSIG
YILHAWMKYPKFGHACASDYAARFVRYGLLSRKEAIELVQKRDHKLDNKCVEDFCNFIGISKTTFWKIVE
KHYNMDLFYKNDFGEFKLKNKLQ
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Molecule Role |
Virulence factor |
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Molecule Role Annotation |
MUTATION: A motile ÃâCj1324 mutant with intact flagella was considerably less hydrophobic, less able to autoagglutinate and form biofilms, and less able to colonize chickens than the parent strain (Howard et al., 2009) |
| References |
Champion et al., 2005: Champion OL, Gaunt MW, Gundogdu O, Elmi A, Witney AA, Hinds J, Dorrell N, Wren BW. Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(44); 16043-16048. [PubMed: 16230626].
Howard et al., 2009: Howard SL, Jagannathan A, Soo EC, Hui JP, Aubry AJ, Ahmed I, Karlyshev A, Kelly JF, Jones MA, Stevens MP, Logan SM, Wren BW. Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. Infection and immunity. 2009; 77(6); 2544-2556. [PubMed: 19307210].
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