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Cj1321 |
| Victor ID |
831 |
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Gene Name |
Cj1321 |
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Sequence Strain (Species/Organism) |
Campylobacter jejuni subsp. jejuni NCTC 11168 |
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NCBI Gene ID |
905613
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NCBI Protein GI |
218562932
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Locus Tag |
Cj1321 |
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Genbank Accession |
AL111168 |
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Protein Accession |
YP_002344711 |
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Other Database IDs |
UniProtKB-ID: Q0P8T6_CAMJE
UniRef100: UniRef100_A3ZGY7
UniRef90: UniRef90_E0QBI2
UniRef50: UniRef50_E0QBI2
UniParc: UPI00000C1EBD
EMBL: AL111168
EMBL-CDS: CAL35435.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj1321
OMA: EDGVVAN
BioCyc: CJEJ192222:CJ1321-MONOMER
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Taxonomy ID |
192222
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Gene Starting Position |
1250851 |
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Gene Ending Position |
1251393 |
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Gene Strand (Orientation) |
+ |
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Protein Name |
putative transferase |
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Protein pI |
8.47 |
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Protein Weight |
18682.81 |
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Protein Length |
180 |
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Protein Note |
Original (2000) note: Cj1321, probable transferase,len: 180 aa; similar to TR:Q46674 (EMBL: U05248) E. coli polysialic acid gene cluster region 2 neuD (207 aa), fasta scores; opt: 267 z-score: 337.2 E(): 1.8e-11, 29.6% identity in 162 aa overlap, some simialrity to e.g. LPXA_BRUAB acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (283 aa), fasta scores; opt: 134 z-score: 173.4 E(): 0.025, 31.6% identity in 95 aa overlap. No Hp match. Also similar to Cj1123c wlaI (30.2% identity in 179 aa overlap). Contains 2x Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats). Upstream region contains a G(10-11) hypervariable tract~Updated (2006) note: No specific characterisation with acceptable identity score has been carried out yet. Putative kept within product function. Identifed as part of Campylobacter jejuni O-linked glycosylation locus (Cj1293 - Cj1342). Literature search identified paper linking Cj1321-Cj1326 as being a glycosylation islet (Champion et al., 2005). Functional classification - Surface polysaccharides, lipopolysaccharides and antigens~PMID:16230626, PMID:11832511, PMID:16573682,PMID:12781527 |
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DNA Sequence |
>gi|15791399:1250851-1251393 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
CGTGAAAAATGTCATCATCATAGGAGCGGGTGGCTTTACTAGAGAGCTTTATTCTTATTTAAAAGATGCA
AATTACGAAATTATAGGCTATATTGATATACAAGAAAATAATTTTTTTGACTTAAAATATCTAGGCAATG
AAGATAATTTCGATAAAAAGTTGATTCAAAAAGCATCTTTTGCTTTAGGTGTAGGACAAATCAATTTAAG
AAAAAAAATCCTTGTAAAACTTTCAAAAAAATCATGTAATTTTATCACTTTTATACATCCTCAATCTTTT
GTTTCAAAAGAAGCTAAAATAGGACAAGGGGTTATAGTGTGTCCTTTTGTAACCATTAATGCTAATTCAA
ATATAGGAGATTTTGTGCTTTGTAATATTTATTCAAGCATAGCTCATGATTGTAAAGTAGGAGAAGGAAG
TATTTTAAGCCCTTATGCTACACTTAATGGAAATTCAAGCATAGGAAAAAATTGTTTTTTAGCTACTAGA
GTTAGCCTGTTGCCTTGCGTAAACTTAGAAGATAACTGCATAGTAAGCAGGTA
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Protein Sequence |
>gi|218562932|ref|YP_002344711.1| putative transferase [Campylobacter jejuni subsp. jejuni NCTC 11168]
MKNVIIIGAGGFTRELYSYLKDANYEIIGYIDIQENNFFDLKYLGNEDNFDKKLIQKASFALGVGQINLR
KKILVKLSKKSCNFITFIHPQSFVSKEAKIGQGVIVCPFVTINANSNIGDFVLCNIYSSIAHDCKVGEGS
ILSPYATLNGNSSIGKNCFLATRVSLLPCVNLEDNCIVSR
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Molecule Role |
Virulence factor |
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Molecule Role Annotation |
MUTATION: colonization of chick ceca by a Ãâ(Cj1321-Cj1325/6) mutant was reduced (Howard et al., 2009) |
| References |
Champion et al., 2005: Champion OL, Gaunt MW, Gundogdu O, Elmi A, Witney AA, Hinds J, Dorrell N, Wren BW. Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(44); 16043-16048. [PubMed: 16230626].
Howard et al., 2009: Howard SL, Jagannathan A, Soo EC, Hui JP, Aubry AJ, Ahmed I, Karlyshev A, Kelly JF, Jones MA, Stevens MP, Logan SM, Wren BW. Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. Infection and immunity. 2009; 77(6); 2544-2556. [PubMed: 19307210].
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