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Cj1279c

Victor ID 829
Gene Name Cj1279c
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 905570
NCBI Protein GI 218562891
Locus Tag Cj1279c
Genbank Accession AL111168
Protein Accession YP_002344670
Other Database IDs UniProtKB-ID: Q0P8X7_CAMJE
UniRef100: UniRef100_Q0P8X7
UniRef90: UniRef90_A1W0R4
UniRef50: UniRef50_A1W0R4
UniParc: UPI00000C1E9A
EMBL: AL111168
EMBL-CDS: CAL35394.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj1279c
HOGENOM: HBG501815
OMA: KLIWRPH
ProtClustDB: CLSK872436
BioCyc: CJEJ192222:CJ1279C-MONOMER
Taxonomy ID 192222
Gene Starting Position 1211676
Gene Ending Position 1212911
Gene Strand (Orientation) -
Protein Name putative fibronectin domain-containing lipoprotein
Protein pI 6.35
Protein Weight 43246.41
Protein Length 411
Protein Note Original (2000) note: Cj1279c, probable fibronectin domain-containing lipoprotein, len: 411 aa; 31.1% identity to HP0746. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Also contains 4x Pfam match to entry PF00041 fn3, Fibronectin type III domain~Updated (2006) note: Specific characterisation with acceptable identity score has not been carried out yet, so putative kept within product function. Functional classification - Pathogenicity
DNA Sequence 
>gi|15791399:1211676-1212911 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
ACTACTGAGCCGCCTTAACTTTGCTTGAAGGTTCTGAACGAAGCCCGGCTGAATCAATAGCAATAACTTC
ATAACTATATTCCACCCCTGGCAAAGCTTTTACATCTTTTAATCGCTTTTCTTTAATGCCTTTAAAAACT
GCATTTTGCTCCCCGCCATAGCGTCTTACTTCATACTCAACAGCTCTAGTATCATTATCACTCCATTCTA
AATTTATCCCTTCGCTTGTACTTTGAGCCAAAATAATACTAGGAGCCAAAGGGTTGCCTAAAGTTTTACC
TTCTACACCATCTTTTGGCATAGGACTTTCAAGACCATCTTTATCCACCATTGTTACTTTATAATACTTG
CTTTTACCTGCTCCTTCTACTATATCCTCATAAGAATTTTTATCAGTCTTTGCCAAAACACTAAAAGGAA
GGAAGCTTGAGCTCGTAGAATAAACTTTATAATAAGAAAAATCTTCATACGTAGGAGCATCCCAAGTTAA
AATGATTTTACTAGAACCATCTGTGCTAGCACTTAAATGCTCAACTTGAGGAGGTAAAGCCTTGCTTGTA
GAACTTACAACTTGACTTGACCCACTCTTTATCCCATTAAAACTCACAGCAATAATTCTATAACTTGAAT
TTTCATTAGGCTTTAAATCACTATCGATGTATTCAGCGTTTAAACGATTTTTTACTTCTGCAATTTTTTT
AAATTCTTTATCATCACCTTTGGTTCTTTCAATAATATAAGAATCAACCCTAAAATCAGGATGCGGACGC
CAAATAAGTTTAATACGATTAGGCAAATTAGTCACAGCTTGAACAAAAGGAACAGCTTCAAGTCTTGGAG
CTGTGCTCACTTCTATAACCTTGCCATCTTCTGAAATTTGTCCTTGCTCATTAAAGCTTTTCATCATATA
ACGATACTTAGTACCAGGCTCTAATTTAGTATCTACATAATGAGTTTGAAACTTATCTTTAATAGTGCCT
ACAAGTTTAAAATCAGGATTTTCATCACTAGAACGATACAAATAAAATCCTTTAATATTTTCATTATATA
AAGGCTCCCATTCAAAAGCAATATTACTCATATCACTAAGACTTTTTAAACTTTCAACCTTTGGCAAGCT
TTCATTTACAGCAGGCTCTTTACTTGAAGCTAGCGAATTCATTTGCGAAACACTACAAGCGCTAAGCAAA
AGAGTTAAAAAACTCAAGTAAAAACTCAAGCGAAATCTTTTCATCA
Protein Sequence 
>gi|218562891|ref|YP_002344670.1| putative fibronectin domain-containing lipoprotein [Campylobacter jejuni subsp. jejuni NCTC 11168]
MMKRFRLSFYLSFLTLLLSACSVSQMNSLASSKEPAVNESLPKVESLKSLSDMSNIAFEWEPLYNENIKG
FYLYRSSDENPDFKLVGTIKDKFQTHYVDTKLEPGTKYRYMMKSFNEQGQISEDGKVIEVSTAPRLEAVP
FVQAVTNLPNRIKLIWRPHPDFRVDSYIIERTKGDDKEFKKIAEVKNRLNAEYIDSDLKPNENSSYRIIA
VSFNGIKSGSSQVVSSTSKALPPQVEHLSASTDGSSKIILTWDAPTYEDFSYYKVYSTSSSFLPFSVLAK
TDKNSYEDIVEGAGKSKYYKVTMVDKDGLESPMPKDGVEGKTLGNPLAPSIILAQSTSEGINLEWSDNDT
RAVEYEVRRYGGEQNAVFKGIKEKRLKDVKALPGVEYSYEVIAIDSAGLRSEPSSKVKAAQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Cj1279c mutants had a significantly reduced adherence to chicken epithelial cells (Flanagan et al., 2009)
References
Flanagan et al., 2009: Flanagan RC, Neal-McKinney JM, Dhillon AS, Miller WG, Konkel ME. Examination of Campylobacter jejuni putative adhesins leads to the identification of a new protein, designated FlpA, required for chicken colonization. Infection and immunity. 2009; 77(6); 2399-2407. [PubMed: 19349427].