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pglH from Campylobacter jejuni subsp. jejuni NCTC 11168

Victor ID 824
Gene Name pglH from Campylobacter jejuni subsp. jejuni NCTC 11168
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 905420
NCBI Protein GI 218562743
Locus Tag Cj1129c
Genbank Accession AL111168
Protein Accession YP_002344522
Other Database IDs UniProtKB-ID: Q0P9C5_CAMJE
UniRef100: UniRef100_D3FMY3
UniRef90: UniRef90_Q5HTX6
UniRef50: UniRef50_A7H2N1
UniParc: UPI00000C1E2E
EMBL: AL111168
EMBL-CDS: CAL35246.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj1129c
HOGENOM: HBG710359
OMA: CLSSRYE
ProtClustDB: CLSK879102
BioCyc: CJEJ192222:CJ1129C-MONOMER
Taxonomy ID 192222
Gene Starting Position 1062130
Gene Ending Position 1063209
Gene Strand (Orientation) -
Protein Name GalNAc transferase/polymerase
Protein pI 8.59
Protein Weight 38681.74
Protein Length 359
Protein Note Original (2000) note: Cj1129c, wlaC, capM, probable glycosyltransferase, len: 359 aa; identical to TR:O52905 (EMBL: AJ000854) C. jejuni 11168 capM (358 aa), 97.2% identical to TR:O86151 (EMBL: Y11648) C. jejuni 81116 wlaC (358 aa), and similar to e.g. AMSD_ERWAM amylovoran biosynthesis glycosyl transerase (351 aa), fasta scores; opt: 360 z-score: 445.6 E(): 1.6e-17, 27.3% identity in 362 aa overlap. No Hp match. Contains Pfam match to entry PF00534 Glycos_transf_1~Updated (2006) note: Characterised in Campylobacter jejuni. Product function modified to more specific family member. This protein acts as the transferase/polymerase of GalNAc(s) to bacillosamine. Putative not added to product function. Identifed as part of Campylobacter jejuni N-linked glycosylation locus (Cj1119c - Cj1130c). Functional classification - Surface polysaccharides,lipopolysaccharides and antigens~PMID:15752194, PMID:16498400, PMID:15184581,PMID:16186480, PMID:16618123, PMID:16547029
DNA Sequence 
>gi|15791399:1062130-1063209 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
TTTAGGCATTTTTAACCTCGGCTATAAGCTTAAGCCATTCTTCTTTGATATGAGAAATTTCAAAGTCTTT
ACACCTTTGTTTGGCATTATTTACAAGTTCTTTTCTAAAATTTTCATCATTTAAAACAAGTTCAAGTTTT
TTAGCAAGTGCTATTTCATCATCACAACCTACCAAAAGCCCATCATGATTATCTTTGATTAAATCCTTAG
CACCATTATAATAAGAACTTGAAATTCTACAAACCTCAAAATACAAACTTTCAATTAAAACCGTTGGCAA
ACCCTCTACAAAAGAACAAAGGCAAAGCACTTTTGCTTTTTCATAAAGAGCCTTGACATTTTCAACGCGT
CCTAAAAAATCAACTTTTATTCCTAAAGATTTTACCTTATATTCAAGTTCTTGTCTTAACTGTCCATCTC
CTGCTATAACAAATTTATAATTTTCTTGTAAATTTTTATCCAAATGCGCTATAGCTTTTAAAAACATTAC
AGGGTTTTTGTTGTGATCTAAACGCCCTATAAAAAGAACCAAATTTTCCTTTTCAAAACTAGAATCAAAA
GAAATTTCATCGCTAAAATGACAAGGGTTTAATAAAAGCTTAACCCTTTTTACAAATCTTTCATAATACA
CCTTATCACTGCTTCCAAGCACACTTAAAGCATCACAAAAAGGATAGCTTACCCTTCTTAAAAAACGCCA
AATTTTAGGTTTTAAATACGCTTCATTGCTATGCTCACTTATAATGAGTGGAGTTTTAAGCCCTATTTTC
GCAGCAATACAAGCAATATTAGTCGTATCCAAAAAAGAAATAAAAACATCAGACTTACTTTCTTTCAAAG
CCTTTCTTAAAGCAAAAAATTTCTTAAAACGACTTGCGATTTTATGATAAAGCGTGTCAAATCTAAATTG
TTCCAAACTTGTAACTTTAACTTCATTTTCAAGCTTATAAAAAGATTCTCCTGCATGAAATTTAATAATA
CTTACTTCATGCTCTTTGCAAAGTGCATTAGCTAAGGTTACTAAAGCACGCTCAGCACCTCCTGAATTTA
AAGTTGCGATAATAAAGCTTATTTTCATCA
Protein Sequence 
>gi|218562743|ref|YP_002344522.1| GalNAc transferase/polymerase [Campylobacter jejuni subsp. jejuni NCTC 11168]
MMKISFIIATLNSGGAERALVTLANALCKEHEVSIIKFHAGESFYKLENEVKVTSLEQFRFDTLYHKIAS
RFKKFFALRKALKESKSDVFISFLDTTNIACIAAKIGLKTPLIISEHSNEAYLKPKIWRFLRRVSYPFCD
ALSVLGSSDKVYYERFVKRVKLLLNPCHFSDEISFDSSFEKENLVLFIGRLDHNKNPVMFLKAIAHLDKN
LQENYKFVIAGDGQLRQELEYKVKSLGIKVDFLGRVENVKALYEKAKVLCLCSFVEGLPTVLIESLYFEV
CRISSSYYNGAKDLIKDNHDGLLVGCDDEIALAKKLELVLNDENFRKELVNNAKQRCKDFEISHIKEEWL
KLIAEVKNA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a Cj1129c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004)
References
Hendrixson and DiRita, 2004: Hendrixson DR, DiRita VJ. Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Molecular microbiology. 2004; 52(2); 471-484. [PubMed: 15066034].