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mprA from Mycobacterium tuberculosis H37Rv

Victor ID 82
Gene Name mprA from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885038
NCBI Protein GI 15608121
Locus Tag Rv0981
Protein Accession NP_215496.1
Other Database IDs UniProtKB-ID: MPRA_MYCTU
UniRef100: UniRef100_A5U123
UniRef90: UniRef90_A0PWB4
UniRef50: UniRef50_A0PWB4
UniParc: UPI00000D5F28
EMBL: BX842575
EMBL: AE000516
EMBL-CDS: CAA17580.1
EMBL-CDS: AAK45257.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
HSSP: P0A5Z6
EnsemblGenome: EBMYCG00000001458
EnsemblGenome_TRS: EBMYCT00000001458
EnsemblGenome_PRO: EBMYCP00000001458
EnsemblGenome: EBMYCG00000070758
EnsemblGenome_TRS: EBMYCT00000070763
EnsemblGenome_PRO: EBMYCP00000068822
GenomeReviews: AE000516_GR
Taxonomy ID 83332
Gene Starting Position 1096815
Gene Ending Position 1097507
Gene Strand (Orientation) +
Protein Name MYCOBACTERIAL PERSISTENCE REGULATOR MRPA (TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN)
DNA Sequence 
>gi|57116681:1096815-1097507 Mycobacterium tuberculosis H37Rv, complete genome
GGTGTCCGTGCGAATTCTTGTCGTTGACGACGATCGTGCGGTGCGCGAGTCGCTGCGCCGGTCGCTTTCC
TTCAATGGCTATTCGGTCGAACTGGCCCACGACGGGGTTGAGGCGCTCGACATGATTGCCAGCGATCGCC
CCGACGCGTTGGTCCTGGATGTCATGATGCCGCGGCTGGACGGCCTCGAGGTGTGCCGTCAGCTCCGCGG
CACCGGCGACGACCTGCCGATTCTGGTGCTGACCGCGCGCGACTCGGTGTCCGAGCGGGTGGCCGGGCTG
GACGCCGGTGCCGACGACTACCTACCAAAGCCGTTCGCCCTCGAAGAGCTGCTGGCACGGATGCGGGCGC
TGCTGCGCCGCACCAAGCCCGAGGATGCCGCCGAGTCGATGGCCATGAGGTTCTCCGACCTGACGCTGGA
CCCGGTAACCCGCGAAGTCAACCGTGGACAGCGCCGGATCAGCCTGACCCGCACCGAATTTGCATTGCTG
GAGATGCTGATCGCCAATCCGCGGCGAGTGCTGACGCGCAGCCGTATCCTGGAAGAGGTATGGGGATTCG
ACTTTCCCACCTCGGGCAACGCGCTGGAAGTCTACGTCGGGTATCTACGCCGCAAGACCGAGGCCGACGG
CGAGCCGCGGCTGATCCACACTGTGCGCGGAGTGGGTTACGTGCTACGTGAAACACCACCCTG
Protein Sequence 
>gi|448824752|ref|NP_215496.2| two-component response regulator MrpA [Mycobacterium tuberculosis H37Rv] MRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGLEVCRQLRGTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKPEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mprA mutant is attenuated in mice (Zahrt and Deretic, 2001).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Zahrt and Deretic, 2001: Zahrt TC, Deretic V. Mycobacterium tuberculosis signal transduction system required for persistent infections. Proceedings of the National Academy of Sciences of the United States of America. 2001; 98(22); 12706-12711. [PubMed: 11675502].