Victors

Cj0629
Victor ID	812
Gene Name	Cj0629
Sequence Strain (Species/Organism)	Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID	904959
NCBI Protein GI	15791989
Locus Tag	Cj0629
Protein Accession	NP_281812
Taxonomy ID	192222
Gene Starting Position	588366
Gene Ending Position	591302
Gene Strand (Orientation)	+
Protein Name	lipoprotein
Protein pI	5.93
Protein Weight	97732.21
Protein Length	978
Protein Note	possible lipoprotein, len: 978 aa; no Hp match. Contains a variable poly-T tract at the N-terminus T(4-5). T5 causes the ORF to start here, T4 allows translation from the upstream ORF Cj0628 (which contains a signal sequence and lipid attachment site). Highly similar to Cj1678 (90.7% identity in 901 aa overlap). Cj1678 has a non-variable poly-T tract in an quivalent position, which could allow translation from Cj1677 (similar to Cj0628)
DNA Sequence	>gi\|15791399:588366-591302 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome TTTGGGGGGGGGGAGTAAAGATAACCCTAAATCTATAATCAATAATTTTAGTAATAGTGGAACTATTCAC TCTAATACTGGTGAAAGTATTTATTTTGGTAACGCCAAAATATCAAGTTTTGTTAATAGTGGGACTATTA AGAGTAAACAAGGTGCAGGAGTAAATATATCTCAAGGAACAAGTATAGAGAATTTTAACAATACCGGAAC CGGAATTATTGAAGGCAAGAGAATGGGTGTAAATGTTCGTTCAACAATAAATACCTTCGTCAATGACGGT TTAATTGCTGCAACGAACGATGGAATACAGATAAATGCTAATGTAAAAACATTAATAAATAAGGGAACCA TAAAAGGAGATGCTATATCTATAAGATCATTAGGTGGAACTATAGAAACATTGACCAATGAAGGCATTAT GTATGGTAAAAGTGCTGGTATTTACATGAACAGAAGTCTTGTTAAAACTCTTACAAATAGCGGTACCATT AATCAAAACAATTCGGCAACTTGGTCTGCTGGTATAAAACTCGAAAATGGTAGTATCATAGAAAATATCA TCAACACAGGATCTATCCGTTCTAATGCTTTTGGAATATCTGTAACTGGTGGTAAATTTGGAACACTTAC CATAAAAGATGGAGGTATGGTTTATGGAAAATACTCGGCAATAGGAGTGGGTCGATCGCAAACTCTAGGA GATTTATATATAGATGGACGTTCAAATAATGGCACAGTAAGTGGAATTTATAGTGAAGAACATGGAATTT TATTAGAGAATAACTCACGAACTCAAAAAATAGAACTTAAAAATGGCGGCATTATAAAAGGTAATATCGA TGGTATAAGATTGATAAACTCGGCCTCTTTAAGTGGAGAAATGATTTTATCTGGCGAAGGTTCTAGGGTA GAAGGTGGAAGAGGTGTTGGTATATTGAATCGAAGTGGAAAAATAGAAGGCTCTATAAAAGTAGAAGATG GAGCAACTGTTACGGCTACTTCGAATCGAGCCATAGCTAACTCTGGCTCAGGAAGTATAACAGGTGGTAT TACTGTTAGTGGGAAAAACACTAAACTTGAAGGAAATATAATCAATACAGGTAATGCTTCTATAGGTAGT GATATCAAGATAGAAGGTGGAGCTAAGGTAGAAGGTGGTCTTGTTAATCAAGGTAATGGAAGTATCTCAG GAAGTGTTCAAGTAAGTGGTGGTAGTAGTATTGATTCCATTACCAATGAGGGTAATGGAGCTATTTCTGG TTCAATTACTGTATATAAAGATAGTAAACTTGATTCTATCACTAACACTTCTACATCATCTACAGGTATA AGTGGTTCTATTACTAACAATAGTGATAATAAACTTGAAATTTCTAATTCAGGTAATATCGGTGGTAAGA TTGAAAGTACAGGTAGTGCTGATATGGTGATTAGCAATAGTAATGGTGGAACTATTAGTGGCGGTATTAG TTCTTCAGGAAGTGGAAGCACTAGTATTTCCAATTCACAAGGCTCAACCATAAATAACGGCATCACTGTT TCAGGATCAGCACAAGTTGAAATCTCCAATCAAGGCTCAGTAGGTAAAGATGAAAATGGTAATACAGTAA CTAACAATGGTAGTGGTAGTGTTGGAATCAAAGATTGGCTTGTTTCTACAGATAAAAACACAGGTAAATT AAACACTGTGGTTATAGGTGGAAGTAGAGCTTTTAATGTAAAAGTAGAAAACATCACCGTAGATCAAAGC AATGTTGATCTTGAAGAGCTAAACGATATAAACAACATCATCTCAGGTGTTAATCAAAACAATATTGGCA ATATAGGAACCAATGGAAGTGGAGAAATATCTTTAAGCTTTGATCCAATAACAGGAAAGCTTACTACAGA TTTTAATCTTAATGCTTCCATATCAGGTGCAACCTTTAGATCTTTAATCTCTACTACTTCAAGAAGATCA ACCTTTATAGATAATGTTATGGGTAATTCTATGCAAAGCTTTGCTTTAGCTTCTTCAAGTAAATCTCAAA GCATCGCTATGTCTGAAAAGGGTAATTTATATGCAGATGCAAGTGATTATATAAAGAGTGATTTAAATAA TGGAAGCTATGGTTCTAATAAAGAACATTCTTTATTCATCCTTCCTTATACTTCTTCACAGAATGTTGAA CTTTCTTTAAATGAAGAAAGTAAAGGACACACTAAAGGAACCATTATAGGTTATTCTACTTTAAAAGACA GTGGAATATATGGTGTGTATGCAGGTTATGAAGATACAAAAATGGGTTCAACTTATTTTGATATTAATAA TAGAACCTATTATGCAGGTTTAAAATACTTTAATACCTTATTTACTACAGAAAAAGGTCAAGAAGTTTAT ATCAAAGCTCAAGGTAAAGCTGCTTTGATTAAAAATGATTTAACTGAAAAAATAGGAAATAATGAAGCTA AAGCTGAACCTAATTCTTATGCTTATGGAGTCAATACAGCCTTAGGTATGAATTTTATTTCTAATAAAGA TATATTCTCTCCTGAAATAGGTCTTGCTTATGAAGGAGGTTATACTGAAGCTTTTTCTATGAAAGACACC ATAGGACAAGCAACAGTTAAAGGTGGAGAAAGAACCTATGCAAACTATTTAAATCTTTTCTCTACTAAAA CAAGTCTTACTTGGTTTAGAGATTGGTTGCCTAATTTAAAAACTTCAGTAGAACTTGGAGCTAAGTTTAA TATCAATCCTAAAGTAGAAGCTGAGGCTAGATTTGGTAATATAAAAGTAAGTGATGAGTTTGATTTACCA AGAGTACAAAAATTTGTAAGCACTTCTTTTATCGTTCCTGTTAATGAAGCTTTCTATTTTAGTTTAAACT ATAATGGAATGTTTGATAAAGATGGCAATACCCATACAGGATTTGCTCAGTTTAATTATCTTTGGTA
Protein Sequence	>gi\|15791989\|ref\|NP_281812.1\| lipoprotein [Campylobacter jejuni subsp. jejuni NCTC 11168] MGGGSKDNPKSIINNFSNSGTIHSNTGESIYFGNAKISSFVNSGTIKSKQGAGVNISQGTSIENFNNTGT GIIEGKRMGVNVRSTINTFVNDGLIAATNDGIQINANVKTLINKGTIKGDAISIRSLGGTIETLTNEGIM YGKSAGIYMNRSLVKTLTNSGTINQNNSATWSAGIKLENGSIIENIINTGSIRSNAFGISVTGGKFGTLT IKDGGMVYGKYSAIGVGRSQTLGDLYIDGRSNNGTVSGIYSEEHGILLENNSRTQKIELKNGGIIKGNID GIRLINSASLSGEMILSGEGSRVEGGRGVGILNRSGKIEGSIKVEDGATVTATSNRAIANSGSGSITGGI TVSGKNTKLEGNIINTGNASIGSDIKIEGGAKVEGGLVNQGNGSISGSVQVSGGSSIDSITNEGNGAISG SITVYKDSKLDSITNTSTSSTGISGSITNNSDNKLEISNSGNIGGKIESTGSADMVISNSNGGTISGGIS SSGSGSTSISNSQGSTINNGITVSGSAQVEISNQGSVGKDENGNTVTNNGSGSVGIKDWLVSTDKNTGKL NTVVIGGSRAFNVKVENITVDQSNVDLEELNDINNIISGVNQNNIGNIGTNGSGEISLSFDPITGKLTTD FNLNASISGATFRSLISTTSRRSTFIDNVMGNSMQSFALASSSKSQSIAMSEKGNLYADASDYIKSDLNN GSYGSNKEHSLFILPYTSSQNVELSLNEESKGHTKGTIIGYSTLKDSGIYGVYAGYEDTKMGSTYFDINN RTYYAGLKYFNTLFTTEKGQEVYIKAQGKAALIKNDLTEKIGNNEAKAEPNSYAYGVNTALGMNFISNKD IFSPEIGLAYEGGYTEAFSMKDTIGQATVKGGERTYANYLNLFSTKTSLTWFRDWLPNLKTSVELGAKFN INPKVEAEARFGNIKVSDEFDLPRVQKFVSTSFIVPVNEAFYFSLNYNGMFDKDGNTHTGFAQFNYLW
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: Cj0629 (capA) mutant had a significantly reduced capacity for association with and invasion of Caco-2 cells and failed to colonize and persist in chickens (Ashgar et al., 2007).
References	*Ashgar et al., 2007:* Ashgar SS, Oldfield NJ, Wooldridge KG, Jones MA, Irving GJ, Turner DP, Ala'Aldeen DA. CapA, an autotransporter protein of Campylobacter jejuni, mediates association with human epithelial cells and colonization of the chicken gut. Journal of bacteriology. 2007; 189(5); 1856-1865. [PubMed: 17172331].


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Cj0629