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Cj0618

Victor ID 811
Gene Name Cj0618
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 904945
NCBI Protein GI 218562269
Locus Tag Cj0618
Genbank Accession AL111168
Protein Accession YP_002344048
Other Database IDs UniProtKB-ID: Q0PAP9_CAMJE
UniRef100: UniRef100_A1VYX9
UniRef90: UniRef90_A1VYX9
UniRef50: UniRef50_B9KDJ6
UniParc: UPI00000C21AD
EMBL: AL111168
EMBL-CDS: CAL34764.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj0618
HOGENOM: HBG391652
ProtClustDB: CLSK700499
BioCyc: CJEJ192222:CJ0618-MONOMER
Taxonomy ID 192222
Gene Starting Position 577607
Gene Ending Position 578254
Gene Strand (Orientation) +
Protein Name hypothetical protein
Protein pI 9.48
Protein Weight 24947.87
Protein Length 215
Protein Note Original (2000) note: Cj0618, unknown, len: 215 aa; no Hp match. A member of the 617 family of C.j. proteins containing homopolymeric tracts; similar to C-terminus of Cj1305c (36.7% identity in 221 aa overlap), Cj1306c (39.1% identity in 220 aa overlap), Cj1310c (33.6% identity in 220 aa overlap) and Cj1342c (43.4% identity in 221 aa overlap). The similarities continue from the upstream ORF Cj0617, suggesting that these two ORFs may encode a single protein, but are frameshifted w.r.t. each other. There is a poly-G tract at thesite of the possible frameshift (577586..577594) and all of the similar genes contain variable poly-G tracts at this position~Updated (2006) note: Literature search identified paper giving functional link to motility. Functional classification - Unknown~PMID:15066034
DNA Sequence 
>gi|15791399:577607-578254 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
TTTGTTTGGAAATTCATATGGCGGATATTTAGCAAATTTATGTGCAAAAATAGCTCCTTGGAGTATTGAT
TTTATATTAGATAATTCTTCTTTTGTTAATTTGTTTGGAAATATTTTTAGACTTATAGGTTTTGGAAAAG
AAATCGATTTTACTAGATATCATGGAACATATGATGATACTTTATTTAAAAATATATTTTTATATTTAAG
TGATAAAACTTATTGGAATAATAATAAATTTTCAAAAAATTATTTTTCAAATGCTAGAAAAATCATAAGA
GAACCATTAAACAAAGAACATCTAATAATACAAAGCTTATACCCAAATCCAAAATATATTTTATATCATA
GTATTTTTGATGAAAGATCTCCTTTTAAAAATAAGGAAAATTTTGTACATATTTTAAAAGAATTAAATTT
TAAAGTAGAATTTTTTGCTATTTCACAAGTTGATAATAAGTTTATTAAAAATTTAAATCATGGAATGGGA
TTGAGCACAAAATTATTTTTTAAAAAACATTTATTGCAAATATTAAAAGAACCTTTGCAAGATAAAATTT
GCAAGAAGGAAGTCTCATATAAATGTGATGAGCTAGTGTATACTTTCAAAGAAGAAAATCATCAAATTAT
TTTAAATATAACAAATTG
Protein Sequence 
>gi|218562269|ref|YP_002344048.1| hypothetical protein Cj0618 [Campylobacter jejuni subsp. jejuni NCTC 11168]
MFGNSYGGYLANLCAKIAPWSIDFILDNSSFVNLFGNIFRLIGFGKEIDFTRYHGTYDDTLFKNIFLYLS
DKTYWNNNKFSKNYFSNARKIIREPLNKEHLIIQSLYPNPKYILYHSIFDERSPFKNKENFVHILKELNF
KVEFFAISQVDNKFIKNLNHGMGLSTKLFFKKHLLQILKEPLQDKICKKEVSYKCDELVYTFKEENHQII
LNITN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a Cj0618 C. jejuni mutant was attenuated for the colonization of the chick caeca (Hendrixson and DiRita, 2004)
References
Hendrixson and DiRita, 2004: Hendrixson DR, DiRita VJ. Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Molecular microbiology. 2004; 52(2); 471-484. [PubMed: 15066034].