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Cj0248

Victor ID 805
Gene Name Cj0248
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 904574
NCBI Protein GI 218561911
Locus Tag Cj0248
Genbank Accession AL111168
Protein Accession YP_002343690
Other Database IDs UniProtKB-ID: Q0PBQ7_CAMJE
UniRef100: UniRef100_A5KGL6
UniRef90: UniRef90_Q5HWL7
UniRef50: UniRef50_E0QET2
UniParc: UPI00000C209D
EMBL: AL111168
EMBL-CDS: CAL34402.1
RefSeq_NT: NC_002163.1
PDB: 1VQR
GenomeReviews: AL111168_GR
KEGG: cje:Cj0248
HOGENOM: HBG394690
OMA: ANSNIET
ProtClustDB: CLSK878700
Taxonomy ID 192222
Gene Starting Position 228945
Gene Ending Position 229802
Gene Strand (Orientation) +
Protein Name hypothetical protein
Protein pI 6.17
Protein Weight 30372.41
Protein Length 285
Protein Note Original (2000) note: Cj0248, unknown, len: 285 aa; no Hp match~Updated (2006) note: Similar to proteins from other bacteria. Literature search identified papers giving structural characterisation and clues to product function. Currently unknown function but may be some kind of hydrolase or signal-transduction protein. Cj0248 has been implicated as a virulence factor and has been shown to play a role in motility. Functional classification -Unknown~PMID:16287129, PMID:15066034, PMID:11298288
DNA Sequence 
>gi|15791399:228945-229802 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
TATGATTGGAGATATGAATGAGCTTTTATTAAAAAGCGTTGAAGTATTGCCACCTTTACCTGATACTGTA
AGTAAGTTAAGAAAATATGTGAGCGAGGCTAATTCAAATATAGAAACTATGAAAGTTGCTGAAATCATTT
CAAGCGATCCGTTGATGACGGCTAAGCTTTTGCAATTAGCAAATTCTCCTTATTATGGTTTTACAAGAGA
AATTACAACCATAAATCAAGTGATTACTTTATTAGGCGTTGGTAATATCATCAATATAGTTATGGCTGAC
TCCATTAGAGATAATTTTAAAATAGACGTTTCACCTTATGGTTTAAATACTCAAAATTTTTTAAAAACGT
GCAATGAAGAGGCAACTTTTATCGCAAATTGGCTTAATGATGAAGATAAAAAACTTTCTCATCTTTTAGT
TCCTTGTGCAATGCTTTTAAGGCTTGGTATTGTTATTTTTTCAAATTTTCTTATACAAAATCATAAGGAT
AAGGATTTTTTAGCTTTTTTAAATAAAAATGAAAATCTTGCTTTAGCGGAGAATGAATTTTTAGGCGTAG
ATCATATTTCTTTCTTGGGATTTTTGTTACATCGTTGGAATTTTGATGATGTTTTGATTGAAAGTATATG
TTTTGTTCGCACTCCTCATGCTGCTCGCGAAAAAGTGAAAAAATCCGCTTATGCTTTAGCAATAACAGAT
CATCTTTTTGCTCCGCATGATGGTTCTTCTCCATTTAACGCAAAAGCTGCAGTTGCTTTACTTAAAGAGG
CAAAAACTCAAGGAATTAATTTTGATTTAAACAATCTTTTATCTAAGCTTCCTAACAAAGCTAAGGAAAA
TTTAAACAAAGAAGATTA
Protein Sequence 
>gi|218561911|ref|YP_002343690.1| hypothetical protein Cj0248 [Campylobacter jejuni subsp. jejuni NCTC 11168]
MIGDMNELLLKSVEVLPPLPDTVSKLRKYVSEANSNIETMKVAEIISSDPLMTAKLLQLANSPYYGFTRE
ITTINQVITLLGVGNIINIVMADSIRDNFKIDVSPYGLNTQNFLKTCNEEATFIANWLNDEDKKLSHLLV
PCAMLLRLGIVIFSNFLIQNHKDKDFLAFLNKNENLALAENEFLGVDHISFLGFLLHRWNFDDVLIESIC
FVRTPHAAREKVKKSAYALAITDHLFAPHDGSSPFNAKAAVALLKEAKTQGINFDLNNLLSKLPNKAKEN
LNKED
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a Cj0248 C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004)
References
Hendrixson and DiRita, 2004: Hendrixson DR, DiRita VJ. Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Molecular microbiology. 2004; 52(2); 471-484. [PubMed: 15066034].