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Cj0019c

Victor ID 802
Gene Name Cj0019c
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168
NCBI Gene ID 904357
NCBI Protein GI 218561712
Locus Tag Cj0019c
Genbank Accession AL111168
Protein Accession YP_002343491
Other Database IDs UniProtKB-ID: Q0PCA6_CAMJE
UniRef100: UniRef100_E1PNG4
UniRef90: UniRef90_Q5HXD9
UniRef50: UniRef50_B9KEG8
UniParc: UPI00000C1FFF
EMBL: AL111168
EMBL-CDS: CAL34200.1
RefSeq_NT: NC_002163.1
GenomeReviews: AL111168_GR
KEGG: cje:Cj0019c
HOGENOM: HBG394682
OMA: ESSIEST
ProtClustDB: CLSK878602
BioCyc: CJEJ192222:CJ0019C-MONOMER
Taxonomy ID 192222
Gene Starting Position 23664
Gene Ending Position 25442
Gene Strand (Orientation) -
Protein Name putative MCP-domain signal transduction protein
Protein pI 5.4
Protein Weight 64064.65
Protein Length 592
Protein Note Original (2000) note: Cj0019c, probable MCP-domain signal transduction protein, len: 592 aa; similar to other proteins containing the MCP domain e.g. HLYB_VIBCH hemolysin secretion protein precursor (548 aa), fasta scores; opt: 418 z-score: 492.5 E(): 3.5e-20, 22.7% identity in 565 aa overlap, and AER_ECOLI aerotaxis receptor (506 aa), fasta scores; opt: 299 z-score: 391.2 E(): 1.6e-14, 25.5% identity in 357 aa overlap. 27.5% identity to HP0103. Contains N-terminal signal sequence and transmembrane anchor around aa 250. Also contains Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain, score 104.90,E-value 1.7e-28~Updated (2006) note: Pfam domain PF00672 HAMP domain identified within CDS. Two probable transmembrace helices identified by TMHMM2.0. Further support given to product function. No specific characterisation with acceptable identity scores has yet been carried out. Thus,putative kept within product function. Functional classification - Signal transduction
DNA Sequence 
>gi|15791399:23664-25442 Campylobacter jejuni subsp. jejuni NCTC 11168 chromosome, complete genome
GTTACTGAAAGCTACTTAATTTTTCGGAGAGTTTAGAGGCACCATTTAGAACATTTTGAGAGATATTATT
GATTTCACATGATAAATCTTTAACAGAATTTGCAAGTTCGTTAACTTTATCTATATTTGTTCCTAAGATA
AGCATTTTATCTTTTACTTCCATGCTTTTATCTTTCATGGTTTGGGTTGATTCTATAGAGCTTTCCAATT
TATGCATAGAATTTACAAGTTCTTGTTGTAAATCATTGGTTTTTGAAGAGGTTTCTTTCATAGAATCATG
GATAAGATCCATTAAGGCTTTGTTGTCATTGATTTGTTGGACTATAGTATTAACAGTAGCATTGATGTTT
AAAAGAGATTTACTTGTTTTATCAGCAAGCTGTCCAACTTCATCGGCTACAACAGCAAATCCACGCCCAT
GTTCGCCTGCTCTTGCAGCTTCGATAGCTGCATTTAGGGCAAGTAAATTAGTTTGATCAGCTATGTCTTT
AATGGAGTTTGTGATTTCTATAATATTATCCGCACTTTGGGTTAGATTGTCCATATTGGCTACTATATTT
TGTTCTTTTTCATTGTTTTCATTTATTAAATTTACAAGTTCAGATAGAGTAAGTTCTACTTTATCCATTA
GTATGTGCATATCTTGCATATTTTCTATACTTTCTTGTGCTAAATTTCCCGCAAGATTGATATGATCATC
TAAAACATGAGTGATTTCTTTAACTCCTTGAATTTGTTCATGTTGCGAATTAGAGCTGTTTTCAAGCATC
ATAGAGTTGTTTTTGAGTTTTTGTGAATTTTGATGACTTGATTTAGCATTTTCTATGGCTTCTATGATTG
AGTTTTGAACGGTGGAAATAAATGAATTAATATATTGAGCACTTTGTCCAAGCTCACTTTTTGGATCTAT
ATTTAAACGAGAGTGTAGATTGGCTTCTTTGCTAGCTAAATTAGCGCTTAGTTTTTCTAAAGTATGAATT
GGCATGATGACTTTTTTTAGTGTTAATAAAATAAAAAATACAAATAATACAAGAGTAATTCCAAATACTG
CTAAAGCGATATAAAATTTAAATAAATTAGATTGTTCTATAGTATTTTGGGTAAAAGTGTTAAGTTGTTT
TAACTCTTTCATGAGAGAATTATTCTCATAAATAGAAGAATTATCTTGCATAATAGAAATTTGCTTTACA
ATCATGTTATAGTGTTTTAAAAAAAGTTGTAAATTTTCACTTTTTGTATCATTTTTGATTTCTTTCATAA
GATTGTTGAGTTGATTTAGTGTTGTTTTTTGTAAAATATTTTCAGTTGAAAGAACGCTTAACATAGAACT
CATTGTTTTATAGTTGTTTTTATTTGTTTCATGGTTTTGTTCCAATTCTTCAAAATAATTTTTAGCTAGT
TCAAATAAATAAAGTTTTGAATTTACTGCTATGGAATTTGCGGATTTAAAATAATTAAGCTGGATTAGTT
TGGCATTAAAAATTTCTTCTGCTTTGTTTATGTCAATCCCAAAAGTTTTAAGTTTTGTAAAGTTTTCTTG
CATTTTTTTTATCGCTTGAACACTTGGATCGTAGTTGATAAAATTAAAACTATTTTGAAAAACAGAATTG
ATTTTTTCATCTGAAATTTCTAGTTGTTGAACTATGTTTATCAATTCTTTATTATCTTTAGATGAAGAAT
AGTTATTAAAAATAATACCTAATAAAACAAGAATGAAAGCTAAAACTAGTGTAGATAAAATAATAAATTT
TATCAAAAATGAACTTTTTTTATTTGTCA
Protein Sequence 
>gi|218561712|ref|YP_002343491.1| putative MCP-domain signal transduction protein [Campylobacter jejuni subsp. jejuni NCTC 11168]
MTNKKSSFLIKFIILSTLVLAFILVLLGIIFNNYSSSKDNKELINIVQQLEISDEKINSVFQNSFNFINY
DPSVQAIKKMQENFTKLKTFGIDINKAEEIFNAKLIQLNYFKSANSIAVNSKLYLFELAKNYFEELEQNH
ETNKNNYKTMSSMLSVLSTENILQKTTLNQLNNLMKEIKNDTKSENLQLFLKHYNMIVKQISIMQDNSSI
YENNSLMKELKQLNTFTQNTIEQSNLFKFYIALAVFGITLVLFVFFILLTLKKVIMPIHTLEKLSANLAS
KEANLHSRLNIDPKSELGQSAQYINSFISTVQNSIIEAIENAKSSHQNSQKLKNNSMMLENSSNSQHEQI
QGVKEITHVLDDHINLAGNLAQESIENMQDMHILMDKVELTLSELVNLINENNEKEQNIVANMDNLTQSA
DNIIEITNSIKDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVGQLADKTSKSLLNINATVNTIVQQI
NDNKALMDLIHDSMKETSSKTNDLQQELVNSMHKLESSIESTQTMKDKSMEVKDKMLILGTNIDKVNELA
NSVKDLSCEINNISQNVLNGASKLSEKLSSFQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a Cj0019c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004)
References
Hendrixson and DiRita, 2004: Hendrixson DR, DiRita VJ. Identification of Campylobacter jejuni genes involved in commensal colonization of the chick gastrointestinal tract. Molecular microbiology. 2004; 52(2); 471-484. [PubMed: 15066034].