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y2285

Victor ID 780
Gene Name y2285
Sequence Strain (Species/Organism) Yersinia pestis KIM 10
NCBI Gene ID 1147232
NCBI Protein GI 22126170
Locus Tag y2285
Genbank Accession AE009952
Protein Accession NP_669593
Other Database IDs UniProtKB-ID: Q8D0E3_YERPE
UniRef100: UniRef100_B0H4Y1
UniRef90: UniRef90_B1JM80
UniRef50: UniRef50_P0AFR3
UniParc: UPI00000E44E9
EMBL: AE009952
EMBL-CDS: AAM85844.1
RefSeq_NT: NC_004088.1
GenomeReviews: AE009952_GR
KEGG: ypk:y2285
HOGENOM: HBG564176
ProtClustDB: PRK11660
BioCyc: YPES187410:Y2285-MONOMER
Taxonomy ID 187410
Gene Starting Position 2521431
Gene Ending Position 2523128
Gene Strand (Orientation) +
Protein Name putative sulfate transporter YchM
Protein pI 8.45
Protein Weight 55549.4
Protein Length 565
Protein Note putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport
DNA Sequence 
>gi|22123922:2521431-2523128 Yersinia pestis KIM 10 chromosome, complete genome
GATGAAAACGCACGGAATTAACGGCATTAGGCCGTTCAGCGCAATTATTGACGCTTGCTGGCGAGAAACT
TATACACTTCAACGACTTTTCAAAGACATAATTGCCGGTGTCACCGTCGGTATTATTGCCATCCCGTTGG
CTATGGCATTGGCGATTGCCAGTGGTGTGCCACCGCAATACGGCTTGTATACTTCGGCTATCGCCGGGAT
CGTGATCGCGGTCAGCGGTGGTTCCCGCTACAGCGTATCCGGCCCTACCGCAGCCTTTGTGGTCATTTTG
TATCCGGTGTCACAACAGTTTGGTCTAGCCGGCTTACTCTTGGCGACAATATTATCCGGTCTATTTCTGC
TCTGTATGGGGTTTGCCCGGCTTGGGCGGTTGATCGAATATATACCGTTATCAGTGACCCTCGGCTTCAC
TTCAGGAATTGCCATCACCATTGCAACCATGCAGGTGAAAGATTTCTTCGGGTTACACCTGGTCGCCGTG
CCAGAAAATTATGTTGGAAAAGTCACCGCCCTCGCACAGGCCATGCCAACGATTAATGTGAGTGATACGT
TAATTGCGACGGTTACCTTGCTGGTATTAATCCTTTGGCCACGGCTGAAACTAAAGTTACCGGGTCACTT
ACCTGCATTAGTCGCGGGTACTGCAGTCATGGGGGTGCTCTCACTGTTTGATCAACAGGTTGCGACTATC
GGCTCACGCTTTGGTTATCTCTTGGCTGATGGGACTCAGGGCCAAGGTATTCCGCCTATTCTGCCGCAGT
TTGTGCTGCCCTGGCAGTTACCTGCCGCAAATGGTCAAGAGTTTGTGCTGAACTGGGCGACACTTTCTGC
ACTGCTGCCCGCCGCCTTTTCAATGGCGATGTTAGGGGCGATAGAGTCCTTGCTGTGCGCAGTCGTCCTT
GATGGTATGACTGGGCAGAAGCATCATTCAAACAGTGAATTGGTCGGTCAAGGGCTAGGCAACATTGTCG
CCCCCTTCTTTGGTGGGATTACCGCAACGGCAGCCATCGCCCGTTCTGCTGCTAACGTCCGCGCGGGTGC
CACCTCGCCGGTATCCGCGATTATCCACGCGGTGCTGGTGCTACTGGCGTTACTGGTACTGGCACCGATG
CTGTCGTACCTGCCATTAGCCGCAATGGCTTCCCTGCTGTTGATTGTCGCCTGGAACATGAGTGAAGCCC
ATAAGGTTATTGACCTGCTGCGCCGTGCGCCTAAGGACGACATCATCATTATGCTGCTGTGTATGAGCCT
CACCGTATTGTTCGACATGGTGATCGCGATAACGGTTGGGATTGTGTTGGCATCATTGTTGTTTATGCGA
CGTATTGCGCAAATGACACGCCTGAGTGAGATACCTGCGGCGGTTAATGATAAGACATTGGTATTGCGAG
TAAACGGCCCGTTGTTCTTCGATGCCGCTGAACGGATATTCAGTGAGTTGCTCACCCGTTGCGATAATTA
TGACACTATTATCCTGCAATGGGATGCTGTGCCCGTTCTCGATGCCGGTGGCTTGAATGCTTTCCTGCGC
TTTACTGAAGCGTTGACAGAGCAGCAACTGCTGGTTATCACAGATATTCCTTTCCAGCCACTGAAGACGC
TGGCCAGAGCCAGGGTGAAGCCAATTTCAGGCAAGTTGAATTTCTATGCTTCTTTACCGGAAGCACTGGC
GGCACTACAGAATAACTA
Protein Sequence 
>gi|22126170|ref|NP_669593.1| putative sulfate transporter YchM [Yersinia pestis KIM 10]
MKTHGINGIRPFSAIIDACWRETYTLQRLFKDIIAGVTVGIIAIPLAMALAIASGVPPQYGLYTSAIAGI
VIAVSGGSRYSVSGPTAAFVVILYPVSQQFGLAGLLLATILSGLFLLCMGFARLGRLIEYIPLSVTLGFT
SGIAITIATMQVKDFFGLHLVAVPENYVGKVTALAQAMPTINVSDTLIATVTLLVLILWPRLKLKLPGHL
PALVAGTAVMGVLSLFDQQVATIGSRFGYLLADGTQGQGIPPILPQFVLPWQLPAANGQEFVLNWATLSA
LLPAAFSMAMLGAIESLLCAVVLDGMTGQKHHSNSELVGQGLGNIVAPFFGGITATAAIARSAANVRAGA
TSPVSAIIHAVLVLLALLVLAPMLSYLPLAAMASLLLIVAWNMSEAHKVIDLLRRAPKDDIIIMLLCMSL
TVLFDMVIAITVGIVLASLLFMRRIAQMTRLSEIPAAVNDKTLVLRVNGPLFFDAAERIFSELLTRCDNY
DTIILQWDAVPVLDAGGLNAFLRFTEALTEQQLLVITDIPFQPLKTLARARVKPISGKLNFYASLPEALA
ALQNN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: YchM mutant is attenuated in mice (Flashner et al., 2004).
COG COG0659P, under P: Inorganic ion transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].