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mma4

Victor ID 77
Gene Name mma4
Sequence Strain (Species/Organism) Mycobacterium tuberculosis CDC1551
NCBI Gene ID 925954
NCBI Protein GI 15840045
Locus Tag MT0670
Protein Accession NP_335082.1
Other Database IDs UniProtKB-ID: Q8VKH2_MYCTU
UniRef100: UniRef100_Q8VKH2
UniRef90: UniRef90_C6DU21
UniRef50: UniRef50_A5U027
UniParc: UPI00000D2B8C
EMBL: AE000516
EMBL-CDS: AAK44896.1
RefSeq_NT: NC_002755.2
HSSP: Q11195
EnsemblGenome: EBMYCG00000069658.
EnsemblGenome_TRS: EBMYCT00000069663
EnsemblGenome_PRO: EBMYCP00000067722
GenomeReviews: AE000516_GR
KEGG: mtc:MT0670
TIGR: MT0670
HOGENOM: HBG687502
OMA: PEDGRMT
ProtClustDB: CLSK790562
Taxonomy ID 83331
Gene Starting Position 737737
Gene Ending Position 738684
Gene Strand (Orientation) -
Protein Name methoxy mycolic acid synthase 4
DNA Sequence 
>gi|50953765:737737-738684 Mycobacterium tuberculosis CDC1551, complete genome
CTTAGGCCGCGGCACCCGGCTTGAGGTAGGTCACCAGGCTGCAGTCGAGCATCTCGTCGGTGAAGTAGTG
CTCGCAGCCACGCAAATACTTCATGTAGCGGTTGTAGACCTCTTCGGAGGTGACCTCGATGGCCTTGTCC
TTATTGGACTGCAGCGTGTCCCCCCAGATCCGCAGCGTCTTGATGTAATGCGGGCGCAACGAGAGCGGCT
CCGGGACGGTGAAACCGGCCTTCTCGCCGTGTTCGACCATCATCTCGGTGGACGGCAGGCGGCCGCCGGG
AAATATCTCGGTGACGATGAACTTGATGAAACGCGCCGTCTCGAAGCTCAGCTTCTTACCGCGGGCCGCC
ATCTCGTAGGGGTGGTAGCTGACGCTGCTCTGGACGGTCATCCGGCCGTCGGCGGGCATGATGTTGAAAC
ACCGCTTGAAGAAGTCGTCGTAGTTCTCGTGCCCGAAGTGCTCGAAGGCTTCGATCGACACAATCCGGTC
GACGGGTTCGGCGAAATCCTCCCAGCCTTGCAGCAGCACTTGACGTGAGCGGTTGGTGTCGATCGAAGCC
AGCACTTGCTCGCAGCGGGCGTGCTGGTTCTTGGACAACGTCAGGCCGATGACGTTAACGTCGAACCGCT
CGACGGCGCGCCTCATGGTGGTGCCCCAACCGCACCCAATGTCCAGCAGCGTCATGCCCGGCTTGAGGTC
CAGCTTGTCCAGGTTGAGGTCGACCTTGGCGTATTGGGCTTCTTCGAGCGTGAGCTCCGGTGGCTCGAAG
TAGGCACAGCTGTAAGTTCGGGTCGGGTCCTGGAACAGGGCGAAGAAATCATCGGAGACGTCGTAGTGCG
CTTGGATGTCTTCGAAGCGTGTCCGTGTCTTGGTTGGGCTAATCGGTTTCTCGGCCATTCTCGTCATGTT
CTCCTGGATGGTGTCAGTTACCGGTGGCTGTGCACCCA
Protein Sequence 
>gi|15840045|ref|NP_335082.1| methoxy mycolic acid synthase 4 [Mycobacterium tuberculosis CDC1551] MGAQPPVTDTIQENMTRMAEKPISPTKTRTRFEDIQAHYDVSDDFFALFQDPTRTYSCAYFEPPELTLEEAQYAKVDLNLDKLDLKPGMTLLDIGCGWGTTMRRAVERFDVNVIGLTLSKNQHARCEQVLASIDTNRSRQVLLQGWEDFAEPVDRIVSIEAFEHFGHENYDDFFKRCFNIMPADGRMTVQSSVSYHPYEMAARGKKLSFETARFIKFIVTEIFPGGRLPSTEMMVEHGEKAGFTVPEPLSLRPHYIKTLRIWGDTLQSNKDKAIEVTSEEVYNRYMKYLRGCEHYFTDEMLDCSLVTYLKPGAAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mma4 mutant is attenuated in mice (Dubnau et al., 2000).
COG COG2230M, under M: Cell wall/membrane/envelope biogenesis
References
Dubnau et al., 2000: Dubnau E, Chan J, Raynaud C, Mohan VP, Lanéelle MA, Yu K, Quémard A, Smith I, Daffé M. Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice. Molecular microbiology. 2000; 36(3); 630-637. [PubMed: 10844652].