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relA from Yersinia pestis KIM 10

Victor ID 763
Gene Name relA from Yersinia pestis KIM 10
Sequence Strain (Species/Organism) Yersinia pestis KIM 10
NCBI Gene ID 1145758
NCBI Protein GI 22124724
Locus Tag y0811
Protein Accession NP_668147.1
Other Database IDs UniProtKB-ID: Q7CKD2_YERPE
UniRef100: UniRef100_A4TPX8
UniRef90: UniRef90_A4TPX8
UniRef50: UniRef50_P55133
UniParc: UPI00000DC624
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM84398.1
EMBL-CDS: AAS60581.1
EMBL-CDS: CAL21969.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO3380
KEGG: ypk:y0811
KEGG: ypm:YP_0306
HOGENOM: HBG594146
OMA: DLGHRCR
ProtClustDB: PRK10872
BioCyc
Taxonomy ID 187410
Gene Starting Position 907607
Gene Ending Position 909841
Gene Strand (Orientation) +
Protein Name GDP/GTP pyrophosphokinase
DNA Sequence 
>gi|22123922:907607-909841 Yersinia pestis KIM 10 chromosome, complete genome
TATGGTTGCGGTACGAAGTGCGCATTTAAACCCAGCGGGTGAGTTTGCTCTTGACGATTGGATTGCCAGT
TTAGGGCTTGCCAATCCGCAGTCATCTGAGCGATTAGCCGAAACCTGGCGTTACTGTGAACAACAGACGC
AAAACCATCCCGATGCCTCGTTATTACTGTGGCGCGGTCTTGAAATGGTTGAAATTCTTTCCACTCTGAG
TATGGATAACGACAGTATGCGCGCGGCGCTGCTGTTCCCGCTGGTAGATGCCAATATCGTGGACGAAACT
ACCCTGACCGAGCAATTCGGTAAGGGGATTACGTATCTGGTACACGGCGTGCGTGATATGGATGCTATCC
GCCAGTTAAAAGCCACTCACAACGATTCCATGAGCTCGGAGCAAGTGGATAACGTGCGCCGTATGTTATT
GGCGATGGTGGAGGATTTCCGCTGCGTGGTGATCAAGCTGGCAGAGCGGATCGCTCATCTGCGTGAAGTC
AAAGATGCACCGGAAGATGAACGTGTTCTGGCGGCTAAAGAGTGTTCCAATATTTACGCACCACTGGCGA
ACCGTTTGGGGATTGGCCAGATTAAATGGGAGCTGGAGGATTTCTGCTTCCGTTATCTGCATCCAGATGA
ATATAAGAAAATCGCCAAATTACTCCACGAGAGGCGTATTGATCGCGAACAATTTATTGATGACTTCGTT
GCTTCATTACATAAGGCGATGGCCGACGAAGGCATTAAAGCCGACATTTATGGCCGACCGAAGCATATCT
ACAGCATTTGGCGCAAAATGCAGAAAAAGTCGCTGGCCTTCGATGAGCTATTCGACGTCCGCGCGGTGCG
GGTGGTGGTGGAACGTTTGCAGGATTGTTATGCCGCGTTAGGGATTGTTCACACGCACTTCCGGCATTTA
CCTGATGAATTTGATGATTATGTGGCCAACCCTAAGCCAAATGGTTACCAATCGATCCATACCGTGGTGC
TTGGGCCACGAGGTAAAACGTTAGAGATTCAGATCCGCACCCGCCAGATGCATGAAGATGCCGAGTTGGG
GGTTGCTGCGCACTGGAAATATAAAGAAGGGGCCGTGGCAGCGGGCCGTTCGAGTTATGAAGGGCGAATC
GCCTGGTTACGTAAATTGATCGCTTGGCAGGAAGAGATGGCTGATTCTGGCGAAATGCTGGATGAAGTGC
GCAGCCAGGTATTTGATGATCGGGTGTACGTGTTTACACCGAAAGGCGATGTGATTGACCTGCCTGCCGG
CTCGACGCCGCTGGATTTTGCCTACCATATTCATAGCGATGTGGGCCACCGTTGTATCGGTGCCAAAATC
AGTGGCCGCATTGTGCCGTTTACTTATCAGTTGCAGATGGGTGATCAAATTGAAATTATCACTCAAAAAC
AGCCAAACCCAAGCCGTGACTGGCTGAATCCTAACCTCGGTTACATCACGACCAGTCGCGGACGTTCCAA
AATTCATAACTGGTTCCGCAAACAAGATAGAGATAAGAATATTCTGGCTGGCCGGCAAATGCTGGATGAT
GAGCTGGAGCATCTGGATATCAGTCTGAAAGAGGCTGAGAAGCTGCTTGTTCCGCGTTACAACATGAATT
CGATGGATGAAGTGTTAGCGGCGATTGGGGGGGGTGATATCCGTCTGAATCAGATGGTGAACTTCCTCCA
GGGCAAACTGAATAAGCCAACGGCAGAAGAGGCTGATCTAGAAGCACTCCGTCATCTGAATAACAAGCAT
CAGCCCGCGCCACGTAACGCCAGCAAAGACAGTGGGCGTATTGTGGTCGAAGGTGTCGGTAACCTGATGC
ACCATATTGCCCGTTGTTGCCAGCCGATCCCCGGTGATCAAATTATCGGTTTTATCACGCAAGGGCGGGG
GATATCGATTCACCGTGCAGATTGTGAGCAGTTGGCTGAATTGGAATCCCATGCACCGGAACGGATTGTC
GATGCAGTCTGGGGCGAAAGCTACTCCAGCGGTTATTCGCTGGTGGTGCGGGTTACGGCTAATGACCGCA
GTGGGTTATTGCGCGATATCACTACGATCCTGGCAAATGAGAAAGTTAACGTACTGGGCGTTGCCAGCCG
CAGCGATACCAAAAAGATGGTGGCGACTATCGATATGGATATCGAGATCTATAACTTGCAGGTGCTGGGC
CGGGTATTGGCCAAACTGAATCAGTTGCCGGATGTCATAGACGCCCGTCGCCTCCATGGCAATTA
Protein Sequence 
>gi|22124724|ref|NP_668147.1| GDP/GTP pyrophosphokinase [Yersinia pestis KIM10+] MVAVRSAHLNPAGEFALDDWIASLGLANPQSSERLAETWRYCEQQTQNHPDASLLLWRGLEMVEILSTLSMDNDSMRAALLFPLVDANIVDETTLTEQFGKGITYLVHGVRDMDAIRQLKATHNDSMSSEQVDNVRRMLLAMVEDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECSNIYAPLANRLGIGQIKWELEDFCFRYLHPDEYKKIAKLLHERRIDREQFIDDFVASLHKAMADEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVERLQDCYAALGIVHTHFRHLPDEFDDYVANPKPNGYQSIHTVVLGPRGKTLEIQIRTRQMHEDAELGVAAHWKYKEGAVAAGRSSYEGRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVIDLPAGSTPLDFAYHIHSDVGHRCIGAKISGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYITTSRGRSKIHNWFRKQDRDKNILAGRQMLDDELEHLDISLKEAEKLLVPRYNMNSMDEVLAAIGGGDIRLNQMVNFLQGKLNKPTAEEADLEALRHLNNKHQPAPRNASKDSGRIVVEGVGNLMHHIARCCQPIPGDQIIGFITQGRGISIHRADCEQLAELESHAPERIVDAVWGESYSSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTKKMVATIDMDIEIYNLQVLGRVLAKLNQLPDVIDARRLHGN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: relA spoT deletion mutants are attenuated in mice (Sun et al., 2009).
COG COG0317TK, under T: Signal transduction mechanisms; K: Transcription
References
Sun et al., 2009: Sun W, Roland KL, Branger CG, Kuang X, Curtiss R 3rd. The role of relA and spoT in Yersinia pestis KIM5 pathogenicity. PloS one. 2009; 4(8); e6720. [PubMed: 19701461].