Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

purH from Yersinia pestis KIM 10

Victor ID 760
Gene Name purH from Yersinia pestis KIM 10
Sequence Strain (Species/Organism) Yersinia pestis KIM 10
NCBI Gene ID 1145449
NCBI Protein GI 22124417
Locus Tag y0502
Protein Accession NP_667840.1
Other Database IDs UniProtKB-ID: PUR9_YERPE
UniRef100: UniRef100_A7FNG6
UniRef90: UniRef90_A1JIJ7
UniRef50: UniRef50_A9IZD0
UniParc: UPI00000CDA75
EMBL: AL590842
EMBL: AE009952
EMBL: AE017042
EMBL-CDS: CAL22315.1
EMBL-CDS: AAM84091.1
EMBL-CDS: AAS63261.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO3728
KEGG: ypk:y0502
KEGG: ypm:YP_3091
HOGENOM: HBG498048
OMA: ASDGFFP
ProtClustDB: PRK00881
BioCyc:
Taxonomy ID 187410
Gene Starting Position 563007
Gene Ending Position 564641
Gene Strand (Orientation) -
Protein Name AICAR formyltransferase; IMP cyclohydrolase
DNA Sequence 
>gi|22123922:563007-564641 Yersinia pestis KIM 10 chromosome, complete genome
ATTAATGACGGAAATGGCGCATGTCGGTGAAGATCATGGCAATACTGTGTTCATCAGCAGCCGCGATGAC
TTCATCATCACGAATTGAGCCGCCCGGTTGGATGACACAAGTAATGCCCACAGCCGCGGCGGCATCAATA
CCATCACGGAACGGGAAGAAGGCATCAGAGGCCATGGCTGAGCCAGCCACTTCCAGCCCTTCATCTGCGG
CCTTGATACCGGCTATTTTCGCAGAGTACACGCGGCTCATTTGGCCGGCACCTATACCGATTGTCATGTT
ATCGCGGGCATAGACAATCGCATTGGATTTAACAAACTTAGCCACTTTCCAGCAGAACAGCGCATCACGC
AGTTCCTGTTCGGTAGGCTGACGCTTGGAAACCACGCGAAGGTCGGCCGCCGTCACCATACCTAAATCGC
GTTCTTGTACCAGCAAACCCCCATTAACACGTTTGAAATCTAAACCTGCTGAACGTGCTTGCCACTGGCC
ACAAGTCAGGACTCGGACATTTTGTTTAGCTGCAAGCAATGCCAATGCATCAGAGCTGACTGTTGGCGCA
ATGATCACTTCGACAAACTGGCGGCTGATGATCGCGCTGGCCGTTGCTGCATCCAATTCACGGTTAAAGG
CGATGATGCCACCGAAAGCTGAGGTTGGATCGGTTTGATAGGCACGTTCATAAGCGGCAAGAATAGAATC
ACCGATAGCCACACCGCATGGGTTGGCATGTTTAACGATCACACAGGCTGGTTCACTGAACTCTTTCACG
CATTCCAGCGCGGCATCGGTATCCGCAATATTGTTATAAGAGAGGGCTTTCCCTTGTAATTGCTGGGCAG
TGGCAACGGATGCCTCTTTGACATCTTCTTCTATATAGAAGGCAGCTTGCTGGTGGCTGTTTTCACCGTA
ACGCATATCCTGCTTCTTTATATAGTTAAGATTTAGGGTGCGAGGGAAGTGGCCGGAAGGCTGTTCCGTA
TCACCATGATAAGGTGGCACCAGTGTGCCGAAGTAGTTGGCGATCATGCTGTCGTAGGCGGCGGTGTGTT
CGAAAGCTTTAATGGCCAGATTGAAGCGGGTGGGGTAAGTCAACGAACCATCATTATTATCAAGCTCAGT
AATAATGGCGGGGTAGTCGCTACTCTTCACCACGATGGCGACATCTTTATGGTTCTTGGCCGCAGAGCGA
ACCATGGTTGGGCCACCAATATCAATATTCTCAACCGCATCTTCCAACGAGCAATCCGGGCGGGCAACCG
TCTGGGCGAAGGGATATAAATTAACGACGACAATATCAATGGGCTGAATGCCATGTTGAGCCATGATGCC
ATCATCCTGACCACGACGACCTAAAATCCCACCATGCACCTTTGGATGCAAAGTCTTCACACGTCCATCC
ATCATTTCCGGGAAACCGGTGTAGTCAGACACTTCGGTAACGGGTAAACCAGCATCAGCCAGCAGGCGGG
CAGTCCCACCGGTGGAAAGTAACTCGATACCGCGTTGAGAAAGTGCTTGGGCGAATTCGATGATACCTGC
TTTGTCAGACACACTGAGTAGAGCACGGCGGATTGGACGGCGTTGTTGCATGGTTTTATCCCTTGGATTT
GGAGTCGCAGTTTTCTTCATTATCA
Protein Sequence 
>gi|22124417|ref|NP_667840.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Yersinia pestis KIM10+] MIMKKTATPNPRDKTMQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purH mutant is attenuated in mice (Flashner et al., 2004).
COG COG0138F, under F: Nucleotide transport and metabolism
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].