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clpB

Victor ID 754
Gene Name clpB
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192509
NCBI Protein GI 56708764
Locus Tag FTT1769c
Protein Accession YP_170660.1
Other Database IDs UniProtKB-ID: Q5NE82_FRATT
UniRef100: UniRef100_Q14FN5
UniRef90: UniRef90_A7N9C8
UniRef50: UniRef50_P74459
UniParc: UPI000049C600
EMBL: AJ749949
EMBL-CDS: CAG46402.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG413133
OMA: KRENDEP
ProtClustDB: CLSK935168
Taxonomy ID 177416
Gene Starting Position 1857771
Gene Ending Position 1860350
Gene Strand (Orientation) -
Protein Name ClpB protein
DNA Sequence 
>gi|56707187:1857771-1860350 Francisella tularensis subsp. tularensis Schu 4, complete genome
TTTATTTAGAGAATATAATATTGTTATTAGCGTCAATATCGACAACTATTTTATCTTCAGCTTTAAACTC
ACCATCTAGAAGTTTTAGAGCCAGAGGGTTTTCTAAGTTGTTTTGAATAGCGCGCTTAAGCGGTCTAGCA
CCAAACACAGGATCAAAGCCAGCATCAGCTAGTTTATCCATAGCTCCAGTTGTGACTTCTAATCCTATAC
TTAGATCTGCTAGACGTTTTTCTAAGCGTTTGATTTGTATTTTAGCTATTTCAGTTATCATCTCTTTGTT
TAGAGGTTCAAAGACAATTGCATCATCAACTCTATTTACAAATTCAGGTCTAAAGTGGCTAAGTACCATT
TCCATTACAGCAGATTTTACTGTTTCATAATCCTGACCTTGCATTTCTTGGATTCGATGTGAACCAAGGT
TAGAAGTCATAACTATTACAGTATTTTTAAAGTCTACTGTTCTGCCTTGCCCATCTGTTAGGCGACCATC
GTCAAGCACTTGTAGTAAGATGTTAAATATATCAGCATGAGCTTTTTCAACCTCATCAAGTAAGATTACA
GAATAAGGTTTTCTTCTAACATGTTCAGTTAGATAGCCGCCTTGTTCATAACCTACGTATCCAGGAGGTG
CGCCTATTAGTCTAGCTACAGAATGTTTCTCCATAAACTCAGACATATCTACTCTAAGCATGGCATCTTC
ATCATCAAACAAAAACTCTGCTAAAGCTTTTGTAAGCTCAGTTTTACCGACACCAGTTGGACCTAAGAAC
ATGAATGAGCCTATAGGTCTATTTGGATCTGATAATCCAGAACGAGATCTTCTTACAGCATTTGATACTG
CTTTTATAGCTTGATCTTGTCCGATTACTCTTTTATGTAAGAAACTTTCCATATTTAGAAGCTTGTCTTT
TTCGCCTTCCATCATCTTAGACACAGGTATTCCAGTAGCTTTTGAAACTACATCAGCAATCTCATTTTCT
GTAACAGATGTTCTTACTAATTTGTTTTCAGAAGGTTCTGCTTCAGTTTCTTCTATTTGTTTAATTTGTG
CTTCTAGCTCAGGTATTTTACCGTATTGTAATTCTGCCATTTTGCTCAAATCACCCACTCTTTGGTACTT
TTCAAGTTCAAACTTGGCTTTCTCAAGCTCTTCTTTTAGTTTACTTGTACCTTGCATCTTAAGCTTTTCA
GCTTTCCAAAGCTCTTCTAGTCCTTTATACTCGGAGTCTAGCCCTTTTATTTCTTGCTCAAGTATCTCTA
AACGTTTTTTAGTAGCATCATCTTTCTCTTTCTTTAGCTGTTCGCGTTGCATTTTCAGCTGGATGATTCT
ACGATATAAGCTTTCCATTTTTTCAGGTTTAGAGTCTATTTCCATACGAATTTGGCTTGCTGCTTCATCT
ACTAGATCTATAGCTTTATCAGGTAGCTGTCTATCTGTGATATACCTATGTGACAAAGTTGCTGCACTTA
CAATAGCTGAATCTGTGATATTTACACCATGATGTAGCTCATATCTTTCTTTTAGGCCTCTAAGTATAGC
GATAGTATCTTCTACAGTAGGTTCATCAACTAGCACTTTCTGGAATCTTCGCTCAAGTGCCGGATCTTTT
TCAACATACTCACGATACTCATCTAAAGTTGTTGCACCAACACACTTTAGCTCTCCTCTAGCTAGAGCAG
GTTTAAGCATGTTACCAGCATCCATAGATCCTTCTGCTTTACCAGCACCTACCATAGTATGTAATTCATC
TATAAAGAGAATTACATTACCTTCTTGTTTTGATAACTCTTTTAATACAGATTTTAGACGCTCTTCAAAA
TCTCCTCTAAATTTAGCACCAGCTAGCAGTGCACCCATATCTAATGATAGTACTTTTTTACCTTTGACAC
CTTCTGGTACTTCATCATTAACTATTCGTTGAGCTAAGCCCTCAACAATAGCAGTTTTACCAACACCAGG
CTCACCTATAAGCACAGGGTTGTTCTTAGTTCTTCTTTGTAATACTTGAATAGTTCTACGGATCTCACTA
TCTCTACCGATTATTGGATCAATTTTTCCTTTTCTCGCTAGATCAGTTAGATCTACCGTGTATTTATCTA
ATGCACCTTTCATATCTTCTTGATTTTGACTACTCACTTTCTCCCCTCCGCGATAATCATTGACTGCTTT
TGTTAATTTTTCTTTTGTAATACCAAATTTGTTATACAGTCCAGTTAAACTTTTGTCTTCTAAAGAGGCT
AATAAGAAAACCTCACTCGAGATAAACTCATCACCATTTTTATTAGCAAGCCCTTGCATTTTATGTAATG
TAGCTATTAAATCTCTAGATGGTGTTACTTGAGGGTTACCTTCTCCAGATAATACCGCAACACTATCAAC
CATATCATTTACAGCTTTTATAAAGTTTTGTATATTAACACCACAAACGCTTAATATAGATATAGCAACA
CTATCATTTTGCTCCAAAAGAGCTTTTAGTATATGTGCTGATGTAAACTCAGTTGCTTTTTGTTGAAAAG
CATAAGATTGAGCCTCAGCTAGAGCTTCTTGTAGTTTTATTGTAAATTTATTTATATCCA
Protein Sequence 
>gi|56708764|ref|YP_170660.1| ClpB protein [Francisella tularensis subsp. tularensis SCHU S4] MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDSVAVLSGEGNPQVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGALDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSLDMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYREYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQIRMEIDSKPEKMESLYRRIIQLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELEKAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDKLLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFMEKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEVEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTSNLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQIKRLEKRLADLSIGLEVTTGAMDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFKAEDKIVVDIDANNNIIFSK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a clpB mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0542O, under O: Posttranslational modification, protein turnover, chaperones
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].