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clpX

Victor ID 753
Gene Name clpX
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192507
NCBI Protein GI 56707750
Locus Tag FTT0625
Protein Accession YP_169646.1
Other Database IDs UniProtKB-ID: CLPX_FRATT
UniRef100: UniRef100_Q5NH46
UniRef90: UniRef90_Q5NH46
UniRef50: UniRef50_Q55510
UniParc: UPI000049C330
EMBL: AJ749949
EMBL-CDS: CAG45258.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG745965
OMA: CGKSQEQ
ProtClustDB: PRK05342
Taxonomy ID 177416
Gene Starting Position 643368
Gene Ending Position 644621
Gene Strand (Orientation) +
Protein Name ATP-dependent protease ATP-binding subunit
DNA Sequence 
>gi|56707187:643368-644621 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGGCTAAAATTCTATATTGTTCTTTTTGTGGTAAATCACAACAAGAAGTCAAAAATATTATCTCAGGA
AGAGATGGTAATATTTGTAACGAATGTGTAAGTAAATGTGCCGAAAAAATTCGTAGTACTGGTAGTACTA
GTGCTGAAGATATCTCATTTGAAAAATTACCAAAGCCAGTTGAAATCAAAAAATACTTAGATGATTATAT
TATCGGTCAAGATAATGCTAAAAAAGTGTTATCAGTAGCTGTATACAATCATTATAAAAGAATTACATCT
AACCTAACAAAAGATGATGATACTGAGCTTAAAAAAAGTAACGTGCTGTTAATTGGTCCAACGGGATCAG
GTAAGACATTATTTGCCCAGACTTTAGCAAAGTTGTTAAATGTTCCTTTTGCTATAGCAGATGCCACTAC
TCTTACTGAGGCTGGTTATGTTGGTGATGATGTTGAAAATATAATTGTTCGACTTTTGCAAAATGCTGAT
TTTGATGTTGCTAAAGCACAAAAGGGTATTATTTATATTGATGAGATAGATAAAATCGCACGCAAATCAG
AAAGTACGTCAATAACTCGTGATGTTTCTGGTGAGGGTGTGCAGCAGGCATTATTAAAACTTATTGAGGG
TACAGTGTCTTCTGTGCCTCCTAAAGGCGGCAGAAAGCATCCTAATCAAGATATGATTCAAGTGGATACT
TCAGATATATTATTTATTTGTGGTGGAGCATTTGCTGGTATCGAGAAGGTTATAAAGCACAGAATGGATA
AGGTCAGTATTGGGTTTAATTCTGATGTTATTCAACAAAAAAATAGCTTAGATAGCGATAAACTTATGCA
AAAGATTGAAAGTGAAGATTTGACTAGATTTGGGCTTATTCCAGAATTGATTGGTCGTTTGCCAATAGTT
ACAGTTCTAAATGAACTCAAAGAAGAAGATTTAGTTAGAATCCTTACAGAACCTAAAAATGCTTTAATTA
AACAGTATATTAAGCTGTTTAAGTTTGATAATGTTAATATTGAGTTTACCGACCAAGCTCTTGTTGAGAT
AGCTAAAAAAGCAATAACTAAAAAGACAGGCGCGAGAGGTCTAAGAACTATTTTAGAAAATGTACTTCTT
GAAGTGATGTTTCATATACCTTCATCTGAAGATATTGAAAAAGTTATTATCAATGACAAAGTAATTCTAG
AGCAGCAAGAACCAATCTTAGCAACAAAAACACAACAGCAAAAACAATTAAAAGATATAATCTA
Protein Sequence 
>gi|56707750|ref|YP_169646.1| ATP-dependent protease ATP-binding subunit ClpX [Francisella tularensis subsp. tularensis SCHU S4] MAKILYCSFCGKSQQEVKNIISGRDGNICNECVSKCAEKIRSTGSTSAEDISFEKLPKPVEIKKYLDDYIIGQDNAKKVLSVAVYNHYKRITSNLTKDDDTELKKSNVLLIGPTGSGKTLFAQTLAKLLNVPFAIADATTLTEAGYVGDDVENIIVRLLQNADFDVAKAQKGIIYIDEIDKIARKSESTSITRDVSGEGVQQALLKLIEGTVSSVPPKGGRKHPNQDMIQVDTSDILFICGGAFAGIEKVIKHRMDKVSIGFNSDVIQQKNSLDSDKLMQKIESEDLTRFGLIPELIGRLPIVTVLNELKEEDLVRILTEPKNALIKQYIKLFKFDNVNIEFTDQALVEIAKKAITKKTGARGLRTILENVLLEVMFHIPSSEDIEKVIINDKVILEQQEPILATKTQQQKQLKDII
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a clpX mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG1219O, under O: Posttranslational modification, protein turnover, chaperones
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].