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FTT1490

Victor ID 751
Gene Name FTT1490
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192492
NCBI Protein GI 56708529
Locus Tag FTT1490
Protein Accession YP_170425.1
Other Database IDs UniProtKB-ID: Q5NEW7_FRATT
UniRef100: UniRef100_A4IXM2
UniRef90: UniRef90_B0TXA6
UniRef50: UniRef50_B0TXA6
UniParc: UPI0000450127
EMBL: AJ749949
EMBL-CDS: CAG46123.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG493309
OMA: TANTFIF
ProtClustDB: CLSK986380
Taxonomy ID 177416
Gene Starting Position 1543155
Gene Ending Position 1544453
Gene Strand (Orientation) +
Protein Name Na+/H+ antiporter
DNA Sequence 
>gi|56707187:1543155-1544453 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGAGTGAATATTTTTTATTTAGTTTGCTAACTGTTGTAGCTGCATTAATGAGTTACATTAACACTAAG
TTTCTAAAGTTACCCAAAGCAATAGGTTTAACAATTCTTTCAATAACCTTTTCGGCACTATGTGCCTCAT
TTTTGAGTCCATCAAATTTTTTAGTAGTTGCTTTATCAAGTTTTGATTTCAAAAAAACTGTTCTTGATGG
AATGTTATCTTTCTTATTATTTGCTAATGCGTTGCATTTTAATATGATTGATCTAAAAAAAGAGTTAAAA
GCTATATTTGGACTTGCAAGTATTGGTCTATTACTATCAGCACTTACAACTGCTATATTAATCTATGGTT
TCTGTCTCCTAGTTGGTTTTGAAATTAGTTTAGGCTATTGCTTAGTTTTTGGAGCGTTGATATCACCTAC
TGATCCAATTGCAGTAATTAGTACACTTGCTGGTAATAAATCTATACCCAAACATATCAAAACACGTGTA
GTTGGTGAATCATTGTTTAATGATGCTACAGGAATTGTCCTTTTCGTAGTATTATCAAATATCGTTTTCT
TTGGTAGTGGTGGTGAATTTGGACAAGCTATTAATGGTCATGGTATTGAATATATTTGGATAATAGCTAA
ACAGATTGGCTCAGAAGCTGGTGGTGGCATACTACTTGGTTATATATTTGCTAGAGTCGCACTTATATTT
CTAAAGACTAATCAAGACTCTGAAACTTCAATTTTTGTCACATTAGCCGTTGCAAGCATGGGATATGTAA
TCGCTCATAGCTTAAATGTATCAGGTCCTATTGCCATGGTAGTTGCTGGTTTATTCATCGGCAATAATCT
TTCAGATCGTAAAAAAACATCTCCAGACCAAGTAGAAAAACTTGATAATTTTTGGATGGTTATCGATAAT
ATGCTTAACTCTTTCCTATTTATACTTATAGGTCTAGAATTAACTAGTATACCATTTAATCATGGTGCTT
TCTGGGTTGGTGCTGCTGGTATATTCATCGTAACATTTGCTAGATTAGTCAGTATATCAATACCAATTAC
TGTAATAGATAAAAAGCTTACTCGAGCTTCAGCTAAAGATAATTTACTCGTAGCTTGGTCTGGAGTCAGA
GGCGGTATATCTTTAGCATTGGCATTATCATTACCTGATGAAGGTAATGTTATAGTTAGTATTACATATA
CCGTAGTTATATTATCAATACTTGCCCAAGGGTCTACCTTAAAAATTGTTCTAAATATAATTTACCCACA
TAACATAACTAAGAAAGCGGCAAATACCGTAGATAACTA
Protein Sequence 
>gi|56708529|ref|YP_170425.1| Na+/H+ antiporter [Francisella tularensis subsp. tularensis SCHU S4] MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANALHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKTRVVGESLFNDATGIVLFVVLSNIVFFGSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDSETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSIPFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVILSILAQGSTLKIVLNIIYPHNITKKAANTVDN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: FTT1490 mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0025P, under P: Inorganic ion transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].