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FTT0944

Victor ID 745
Gene Name FTT0944
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192455
NCBI Protein GI 56708041
Locus Tag FTT0944
Protein Accession YP_169937.1
Other Database IDs UniProtKB-ID: Q5NGA5_FRATT
UniRef100: UniRef100_Q14HQ7
UniRef90: UniRef90_A7NCV8
UniRef50: UniRef50_A7NCV8
UniParc: UPI000049C401
EMBL: AJ749949
EMBL-CDS: CAG45577.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG482586
OMA: SANIVNK
ProtClustDB: CLSK934763
Taxonomy ID 177416
Gene Starting Position 955056
Gene Ending Position 956438
Gene Strand (Orientation) +
Protein Name AMP-binding family protein
DNA Sequence 
>gi|56707187:955056-956438 Francisella tularensis subsp. tularensis Schu 4, complete genome
ATTGCTACAAAAAATGATTCAGCTCGATAAATTTTTGGCAAATATTAAAAATTATGGCAAAAATAACTAT
ATCTTCTTTGAAGATAAAAGATATGACTATGTTGAAATTCTACAAATATCATATAGTCTAGCGAGATTTT
TGGAATCTTATGGCTATAGGAAAGTATATTCAAATCTTAAAAATTCACCATTATTAGTGAGTTTGTATAT
AGCTAGTTGGATAGCTGATATAGATCTTTTTGTACCAATCAACCCAAGATTAGTCGATAACGAGCTAGCA
GCAATAGTAGATGGTGATAGTTTGTTTATAACAGATAAAATATCTAATCTTGAAGTAAATAAATTATATA
TAGAAAATGCAACATGTTTTTTTGAGAGCCTTGAATATACACAAGATTATATAACTCATGCTAAAGCTCT
TACAGCACATGTAAGCTCAGGGACAACAGGATTTTATCAAAAATATCTTCATAAAATTGATCAGATAATT
AAATATGCTAATGATAGAATCGCTGATTTAGGTCTCAAACAAGATGATCATTTGCTAGTAGCATTATCGA
TAAATCATGCTTTTGCTTTTTCTTATCAAATTTTACCAGCATTAGCTATAGGATTAGATATAACAATAAT
CCGCGAGTTCGATGCTAAGTTAGTAGCACGGATTATTAACCAAAATAGTGTAACCGCTTTAGCATTGTTA
CCGATAATGTATCATTTTTTGTTAGAGCAAAATATTAACAAAAATCATAACCTACGCTACCTAAGTGTTG
CTGGTGATGTCGCTAGTATAAGCTTAGTAACAGCTGTAAAAGATAAATTAGGCTTACCATTACTAAATGG
TATAGGTATGACAGAAGTCTTTGGTTATGGTCAAAATATATCTGCTAATACAGTTAATAAAGTTAAAATA
TTCTCAGATACTGAAGTAAAAATACTTAAATTTGAAAATAGTAACTATGGTAAAATCTTCATCAAAAATA
ATATGCTACCTCTAAATATCGAAACTGAGTGGTTAGAAACTGGAGATATTGGTAGTTTTGATCACCAAAG
CTATGAGCTTAGTTTTTATGGTCGCTATAAGGATATAATTATTAAAGGCGGCTCTAATATATCTCCGTTT
GAATTAGAAACAGCAATTTTAAAAATACCAAATATTGATAATTGCATAGTTACTTCTAAAAAGGATAAAA
TATGGGGAGAAACTGTTTGGGCATATTTGGTAGCATCGCAACAATACTCATTAGAGTTTATAAATAACCA
GCTAAGAAATTATATAGCTGAATACAAAAAATTAGATGGAATTATTTATATTGATGAAATCCCAATAACT
ACAACAGGTAAAACTAATAGAAAAAAAATAAAAGAAATGATTAATCATGAGTA
Protein Sequence 
>gi|56708041|ref|YP_169937.1| AMP-binding protein [Francisella tularensis subsp. tularensis SCHU S4] MLQKMIQLDKFLANIKNYGKNNYIFFEDKRYDYVEILQISYSLARFLESYGYRKVYSNLKNSPLLVSLYIASWIADIDLFVPINPRLVDNELAAIVDGDSLFITDKISNLEVNKLYIENATCFFESLEYTQDYITHAKALTAHVSSGTTGFYQKYLHKIDQIIKYANDRIADLGLKQDDHLLVALSINHAFAFSYQILPALAIGLDITIIREFDAKLVARIINQNSVTALALLPIMYHFLLEQNINKNHNLRYLSVAGDVASISLVTAVKDKLGLPLLNGIGMTEVFGYGQNISANTVNKVKIFSDTEVKILKFENSNYGKIFIKNNMLPLNIETEWLETGDIGSFDHQSYELSFYGRYKDIIIKGGSNISPFELETAILKIPNIDNCIVTSKKDKIWGETVWAYLVASQQYSLEFINNQLRNYIAEYKKLDGIIYIDEIPITTTGKTNRKKIKEMINHE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: FTT0944 mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0318IQ, under I: Lipid transport and metabolism; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].