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FTT0945

Victor ID 744
Gene Name FTT0945
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192454
NCBI Protein GI 56708042
Locus Tag FTT0945
Protein Accession YP_169938.1
Other Database IDs UniProtKB-ID: Q5NGA4_FRATT
UniRef100: UniRef100_Q14HQ6
UniRef90: UniRef90_A4IXQ3
UniRef50: UniRef50_Q14HQ6
UniParc: UPI000049C402
EMBL: AJ749949
EMBL-CDS: CAG45578.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG507440
OMA: VNYTYRL
ProtClustDB: CLSK934764
Taxonomy ID 177416
Gene Starting Position 956431
Gene Ending Position 958194
Gene Strand (Orientation) +
Protein Name chorismate binding family protein
DNA Sequence 
>gi|56707187:956431-958194 Francisella tularensis subsp. tularensis Schu 4, complete genome
CATGAGTAATAATCAATTACCACAATTTGCAATTCTTGAAGATACTCTAACTGATAAACAAAAATATTAT
TTTTATAATCCGATTGCAGAGGTTATAGCTAATAGTAAGGAGACACTTGAGTTAGCTTTTTATCAATTAG
AAAAGCTTCAGCAGCAAAGGTTATATCTAGTTGGATATTTAAGCTATGAAGCCAGTTATTACCTTAATAA
CAATCTTTATGATTTACGTGATCCTGATGATAGTAAATTACTTCATTTTGTCGCTTTTAGTGATTACTCA
AACGAAATCCCAGATGATTTAATTTCAGATAAAAACATAGATATGATGATAGATAGCCTTAATTTTGCAG
ACTATCAAAAAAGCTTTGACAAAGTTCAACAAGCACTTATCGATGGTGAAAGCTATCAGATTAATTTAAC
TAAAAATATCTTAGCTACTACAAAGCTTACTAGCTATGAGTTGTACAATAAGCTCAAACAACAACAATCA
GTTAAATATGCTGCATATTTACCATTTTTAAACCCAGATATAATATCAATATCACCTGAACTTTTCTTTA
AAAAAGATGCTGAAAATTTGGTTGTTAACCCAATGAAAGGTACAGCAAGGCTTACTGGCAATGAATTGAA
AGATCTAAAGATATATCAAGAATTAGCCTTATGTGATAAAAATAGGGCAGAGAACTTAATAATTGTTGAT
CTTTTGCGTAATGATTTATCTGCTATTGCAAAAACTCATACTGTTAAGGTAGATAAACTTTTCTCAATAG
AGAAATACAAAAATCTACTACAAATGACTTCGCAAATTTCAGCAAAAGTAGATAAACAAATATCTTTTAG
GAAGATTCTAGATGGCTTATTTCCTTGTGGTTCGATTACAGGAGCTCCTAAAAAACGAACTATGGAACTA
ATCAAACAAATAGAAAAAGGTAAAAGGGGAGTTTATACCGGAAGCATTGGCTATATTATGCCAAATAATG
ATATGTGCTTTAATGTTGCTATTCGTACTATTCAAAAATATCGAGATAACTTACAAATTGGCGTAGGTGG
CGGTATCACGGTATATTCGGATTTACAGTCAGAATGGCAAGAAATGAATACCAAGATAAACTTTATACGC
CAAATTTATCAGCCAGATTTTTGCTTAATTGAGAGCCTTTATTACTGTAATCAATTTAGAGATTTAGAGC
TACATTTAGAGAGGCTTGAGGACTCTGCTAGACAGTTATTTTTTGATATTGATATTTGCAAGATTAGAGA
TCAACTATATGACTATGTAGAAAAATTAACTGATGATAAAGAATATAAAATCCGTATAGAATATCATTAT
GATAAATCTATAATTATTGAGCATACTCAAATTGATACTACCAACCAACAAGCTATTAAGCTAATAATTT
GTCCTGAGAAAATAAACTCAGCTAATAAATTATTTCAGCACAAAACTACTCATAACTCGACACGAGGCTT
TTATACTCAAATGCATCAAAAGTATATTCAAGATAAAAATTGTGAACTTATTTATCTAAATGAAAAAGAT
AATATTACTGAAACTAGATTTCATAATATAATTATTGAGAAAAATGATAAATTCTACACGCCAAAATTAG
AAGATGGTGTTTTAGCCGGTATCGCGAGAAAATCATTAATCAAACAAGGTAAACTGCAAGCAAAAAGCCT
AAATTTAAATGATCTAAAAACCGCTGATAAAATATATCTTATCAATAGTGTTAGAGGTTTGATACCAGCG
TATTTGAGGATTTA
Protein Sequence 
>gi|56708042|ref|YP_169938.1| chorismate binding family protein [Francisella tularensis subsp. tularensis SCHU S4] MSNNQLPQFAILEDTLTDKQKYYFYNPIAEVIANSKETLELAFYQLEKLQQQRLYLVGYLSYEASYYLNNNLYDLRDPDDSKLLHFVAFSDYSNEIPDDLISDKNIDMMIDSLNFADYQKSFDKVQQALIDGESYQINLTKNILATTKLTSYELYNKLKQQQSVKYAAYLPFLNPDIISISPELFFKKDAENLVVNPMKGTARLTGNELKDLKIYQELALCDKNRAENLIIVDLLRNDLSAIAKTHTVKVDKLFSIEKYKNLLQMTSQISAKVDKQISFRKILDGLFPCGSITGAPKKRTMELIKQIEKGKRGVYTGSIGYIMPNNDMCFNVAIRTIQKYRDNLQIGVGGGITVYSDLQSEWQEMNTKINFIRQIYQPDFCLIESLYYCNQFRDLELHLERLEDSARQLFFDIDICKIRDQLYDYVEKLTDDKEYKIRIEYHYDKSIIIEHTQIDTTNQQAIKLIICPEKINSANKLFQHKTTHNSTRGFYTQMHQKYIQDKNCELIYLNEKDNITETRFHNIIIEKNDKFYTPKLEDGVLAGIARKSLIKQGKLQAKSLNLNDLKTADKIYLINSVRGLIPAYLRI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: FTT0945 mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0147EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].