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emrA1

Victor ID 733
Gene Name emrA1
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192360
NCBI Protein GI 56708319
Locus Tag FTT1257
Protein Accession YP_170215.1
Other Database IDs UniProtKB-ID: Q5NFH7_FRATT
UniRef100: UniRef100_Q14GX9
UniRef90: UniRef90_A0Q7E2
UniRef50: UniRef50_B0TYF7
UniParc: UPI000049C4D2
EMBL: AJ749949
EMBL-CDS: CAG45890.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG624965
OMA: HAVPDKA
ProtClustDB: CLSK934925
Taxonomy ID 177416
Gene Starting Position 1279037
Gene Ending Position 1280059
Gene Strand (Orientation) +
Protein Name HlyD family secretion protein
DNA Sequence 
>gi|56707187:1279037-1280059 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGTCAGAAGAAAAATTACAACAATCAACAATCACAAGAAATAAAAAAAGCTCGAGATTTTCGCCTAAG
AAAATTATCATTGGCTCTAGCATTATTACAATTACAGCTTTAGGAATCTATGGTTATTATAAATATAACA
AGATCTTCCCTAGTACTGATAATGCTTATGTTAATGCTGATATAATTAGTATTTCACCTAAAGTTGGTGG
ATATATAGAAAAAGTCTATATCCACAACAACCAATTTGTTCACAAAGACGATAAACTTGTTCAGATTGAT
CCTAAAGATTATCAACTAAAAGTAGCTCAAGCAAACTCAAAAATTATCCAAACTAAAGGGCAATTAGCTA
TAGCTCAAGAACAAGTAAATGTAGCTAAGTCAAACCTAACTAAAGCACAGTCATCTTTAGATACTGCAAC
AAGTATGGCAGATAGATATATTAAACTTTACAAAGATGATGCTGGCTCTTTACAAGATGCACAAAAATAC
ATAAACCAAAAGATCCAAGCTCAGAAAGCAAAAGATGAAGCTTACTCATCACTTAAGCAAGCCTTATTAC
AAGTTGAAATTGCCAAAGCACAAATTGGTGCAGCCAAACTAAGCTATGATAATGCCAATCTAAATCTAGG
TTATACAACATTGATAGCTCCTGATGATGGCTATGTATCAAATTTAAAACTTTACAAAGGACAACTAGTA
TCACCTGAACAAGCATTATTTGGTTTTATTGATAATAAAAAATGGTGGATAGACGCTAACTTTAAAGAAA
CAGATCTTGATAGAATCAAGCCAGGGCAAAAAGTTGAAATTGAGCTAGATATGTATAGCCATAGTTACGC
TGGCAAAGTTGATAGTATCAGTTATGCTACTGGCTCAGTATTCTCATTACTACCACCTGAAAATGCTACT
GGAAACTGGGTAAAAGTCACTCAGCGCTTCCCAGTAAAAATAATCCTAAAAAATGATCCTAAATACCCAC
TCAGAGTTGGAGCAAGTGCAACAGTAAAAGTAGATACATTATA
Protein Sequence 
>gi|56708319|ref|YP_170215.1| HlyD family secretion protein [Francisella tularensis subsp. tularensis SCHU S4] MSEEKLQQSTITRNKKSSRFSPKKIIIGSSIITITALGIYGYYKYNKIFPSTDNAYVNADIISISPKVGGYIEKVYIHNNQFVHKDDKLVQIDPKDYQLKVAQANSKIIQTKGQLAIAQEQVNVAKSNLTKAQSSLDTATSMADRYIKLYKDDAGSLQDAQKYINQKIQAQKAKDEAYSSLKQALLQVEIAKAQIGAAKLSYDNANLNLGYTTLIAPDDGYVSNLKLYKGQLVSPEQALFGFIDNKKWWIDANFKETDLDRIKPGQKVEIELDMYSHSYAGKVDSISYATGSVFSLLPPENATGNWVKVTQRFPVKIILKNDPKYPLRVGASATVKVDTL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: emrA1 mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG1566V, under V: Defense mechanisms
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].