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FTT0056c

Victor ID 715
Gene Name FTT0056c
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192153
NCBI Protein GI 56707235
Locus Tag FTT0056c
Protein Accession YP_169131.1
Other Database IDs UniProtKB-ID: Q5NIL1_FRATT
UniRef100: UniRef100_Q14K14
UniRef90: UniRef90_A7NEI2
UniRef50: UniRef50_B0TWR9
UniParc: UPI000049C1AF
EMBL: AJ749949
EMBL-CDS: CAG44689.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG613383
OMA: SISTYIF
ProtClustDB: CLSK986250
Taxonomy ID 177416
Gene Starting Position 58245
Gene Ending Position 59549
Gene Strand (Orientation) -
Protein Name major facilitator superfamily (MFS) transport protein
DNA Sequence 
>gi|56707187:58245-59549 Francisella tularensis subsp. tularensis Schu 4, complete genome
ATTAGTCTTTCTTATCTTTTATCATTACTAATATTACAAGAGAAGCAATCATGCTTGCGACTAGAGTTGT
AAATGCAAAATGATATGACTCTAATTCAAAGTACTTAATATCAGCACTACTAGTATATTGAGAAACAACT
TCTCCAGCTTTATTTATATACTTACCAGTCCATGACCAATCTAAGAAATATCCTATAAGTGGATCAAATA
TTGCGCCTAAAATTGGTTCACCTGTATTGATGAAAGCAGCTACAGTTGCAGTTATAATTATAGGATTTAT
ACGATTTCCTATTGCAAATGAAAGCATATAAATTCCTAAGCATAGACCAAAGATAAATAACAGTATTGCT
GATATGGTAGAGCTTGTTTTTGTTAATAAAACAAAGCTAAGAGCTATTGTTCCAATTATGTGGGAGAAGA
TCATCACTCCCTTTCTGCTATCAAGAATTTCAGATAATTTACCAATAATTGGTGAGCCGATAGCCATACC
GATAAAAATCATCGAAATTATGCTAGCAGCTTCTTCTCTTGAAATGTGATATGCTTCTCTGAAGTAAGCG
TTACCCCAAAATCCAGCAAAAGCATCAACCGCCGTGAAGCTTAAGCCGACATAAAATGTTAAAAGCCAGT
TGTTTTTATTTTTGATAACTTCTTTGAGGACATCAAGAGTTTTTAGCTGGTTGTTAGGTGAGCTCGCTTC
GGGTTGCTTAGGATTAAAATCACGTACAACAATATAATAAACTACTGCGATCAATAAGCTAGCCACTGAA
AACAGTAGCATAGCCATTTTCCAGTCGCCACAAATTGTTATAAGATAAGCTAATGGTGCTTGCGCACACA
AGGCACCAATCATTGCTGCTGTAGCAAGAAAGCTTGCGGCAAAGGCAAATTTGCGTGGCTCAAACCATAC
CGATACAGCTTTAAGATAAGATATCGTAGCAAATGATACACCTAAACCAGTAGTTATCCTTGCAATGTAT
GCCATACTAAGACTACCTAAGTTTGCTGCAACAACGAATAATATAACACCTGTTGCTGAAATTATGATTG
AAATCGGGCTTATTAGTCTAAAACCAAATTTATCAATGATAGGCCCAGCTAAAAAAAGTTGACAGATAAT
AATGGACCAGAAAAATGCTGAACCTAAAGCTCCAGTTTGTGTAGCATTGGTACCAAAATTAGACATCATA
TCATCAGTAATTAGACTTGGAAATACTTGCATTACATACTTGTCAAATAGTAGAAATGAACTAAGTATGA
TTATTATCCATGCGTAGCCACGTATATTGTATATCCTTTGTTCCA
Protein Sequence 
>gi|56707235|ref|YP_169131.1| major facilitator transporter [Francisella tularensis subsp. tularensis SCHU S4] MEQRIYNIRGYAWIIIILSSFLLFDKYVMQVFPSLITDDMMSNFGTNATQTGALGSAFFWSIIICQLFLAGPIIDKFGFRLISPISIIISATGVILFVVAANLGSLSMAYIARITTGLGVSFATISYLKAVSVWFEPRKFAFAASFLATAAMIGALCAQAPLAYLITICGDWKMAMLLFSVASLLIAVVYYIVVRDFNPKQPEASSPNNQLKTLDVLKEVIKNKNNWLLTFYVGLSFTAVDAFAGFWGNAYFREAYHISREEAASIISMIFIGMAIGSPIIGKLSEILDSRKGVMIFSHIIGTIALSFVLLTKTSSTISAILLFIFGLCLGIYMLSFAIGNRINPIIITATVAAFINTGEPILGAIFDPLIGYFLDWSWTGKYINKAGEVVSQYTSSADIKYFELESYHFAFTTLVASMIASLVILVMIKDKKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: FTT0056c mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG2223P, under P: Inorganic ion transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].