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FTT0053

Victor ID 714
Gene Name FTT0053
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192152
NCBI Protein GI 56707232
Locus Tag FTT0053
Protein Accession YP_169128.1
Other Database IDs UniProtKB-ID: Q5NIL4_FRATT
UniRef100: UniRef100_A4IW13
UniRef90: UniRef90_A4IW13
UniRef50: UniRef50_B0TWR9
UniParc: UPI0000450199
EMBL: AJ749949
EMBL-CDS: CAG44686.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG613383
OMA: NAGRESH
ProtClustDB: CLSK986250
Taxonomy ID 177416
Gene Starting Position 54953
Gene Ending Position 56251
Gene Strand (Orientation) +
Protein Name major facilitator superfamily (MFS) transport protein
DNA Sequence 
>gi|56707187:54953-56251 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGAAATTACATAATATAAAGGGCTATGCTTGGATTGTAGTTGGGTTAAGCTCATTTCTACTAATCGAT
AAATATATAATGAATGTTTCTCCTAGCTTGATTGCTAATGAGCTTATGAGTAGTTTTTCAATAAATGCTA
CTGAAATGAGTGCGATGGTTTCGTTATTTTTATGGTCTGTAGTATTTTGTCAATTTTTTGTTGCTGGACC
TATCATTGATAAATTGGGGTTTAGAAAAGTAAGTTTTTTCTCATTAATATTATCTGCAATTGGATTATTA
TTATTTGTATTATCTGCAGATATTCACAGTTTTGCACTAGGTTGTGTTTCAAGACTAATGATAGGTATTG
GAGCCTCATTTGCAACAGTCGGCTATATAAAAGCCGCTGCAGTATGGTTTGATCCACGCAAGTTTGCTTT
TGTATGTAGCTTTCTGATGACAGCAGCTATGACTGGTGCATTGTTGGGTCAGGTACCGCTAGTTTATCTA
ATTGAGCTTACAGGATCATGGCATAGAGCATTAATCAGTTATGCTTGCTTTAGTATTGTTATAGCACTTT
TATACTTAGCATTAGTTAGAGATTACAATCCTGATGCTTCATACTCAAACCAAACAAAAGGTAATACTGG
AACGCTTGCTGGAATAAAAAAAGTTCTTTTAAATAAAAATAATTGGTATCTTACATTGTATACCGGTCTT
ACTTTTACCACGATAGATGTTTTTGGCGGAATTTGGGGTAATAACTATTTTAGAGAGTTATATAGCATAC
CGGCAAAAGATGCCTCGTATATTGTTTCGATGATGTTCTTGGGTCTTGCGATTGGCTCACCTATAATTGG
TAAGCTCTCAGAGAAATTTGATAATAGGGTTGGGATTATGGTTGCCTTTCATATTATTGCAACAATTTCT
TTAGCGGTAGTTCTACAATTTAAGCTTACACCAACAATATCTGGAGTTTTACTATTTGTTTTTGGCTTCT
GCTTAGGAGTTTATATGCTAGCTTTTGCTATAGGAAACCGTATAAATCCAGTTGTGGTCGCTGCAACAGT
TGCGGCATTGATAAATACTGGTGAGCCATTATTAGGAGCTTTATTTGATCTATTAATAGGCCATTTGTTA
GATTTGACATGGACAGGCCAATATATAGATGCACAAAATCATATTAGTGCTATAGCTTCAGAGGGGGCGC
ATAGATATTTCCATATAAATGCATATCATCATGCTTTTTTAATCCTTGTATTTAGCATGATCGTATCATT
CTTTTTGCTGATTTTAGTAAAAGATAAAGAAGTTAAATA
Protein Sequence 
>gi|56707232|ref|YP_169128.1| major facilitator transporter [Francisella tularensis subsp. tularensis SCHU S4] MKLHNIKGYAWIVVGLSSFLLIDKYIMNVSPSLIANELMSSFSINATEMSAMVSLFLWSVVFCQFFVAGPIIDKLGFRKVSFFSLILSAIGLLLFVLSADIHSFALGCVSRLMIGIGASFATVGYIKAAAVWFDPRKFAFVCSFLMTAAMTGALLGQVPLVYLIELTGSWHRALISYACFSIVIALLYLALVRDYNPDASYSNQTKGNTGTLAGIKKVLLNKNNWYLTLYTGLTFTTIDVFGGIWGNNYFRELYSIPAKDASYIVSMMFLGLAIGSPIIGKLSEKFDNRVGIMVAFHIIATISLAVVLQFKLTPTISGVLLFVFGFCLGVYMLAFAIGNRINPVVVAATVAALINTGEPLLGALFDLLIGHLLDLTWTGQYIDAQNHISAIASEGAHRYFHINAYHHAFLILVFSMIVSFFLLILVKDKEVK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: FTT0053 mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG2271G, under G: Carbohydrate transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].