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xerD

Victor ID 710
Gene Name xerD
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192118
NCBI Protein GI 56707324
Locus Tag FTT0154
Protein Accession YP_169220.1
Other Database IDs UniProtKB-ID: Q5NIC2_FRATT
UniRef100: UniRef100_Q14JS5
UniRef90: UniRef90_A7NEA9
UniRef50: UniRef50_P44630
UniParc: UPI0000450334
EMBL: AJ749949
EMBL-CDS: CAG44787.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG727654
OMA: YLAFRVE
ProtClustDB: CLSK934390
Taxonomy ID 177416
Gene Starting Position 170082
Gene Ending Position 170960
Gene Strand (Orientation) +
Protein Name Integrase/recombinase
DNA Sequence 
>gi|56707187:170082-170960 Francisella tularensis subsp. tularensis Schu 4, complete genome
AGTGTCCTCAGCTGTTGATGCTTTTCTTGATAATCTCTGGCTTGAGCATGGATTAAGCCAAAATACTATT
TCATCTTATCGTACTGATCTTAAATTCTTACAAAATTATTTTGCAAAAACTGATTTAATTAGTTTAGATT
TTGAGCAGTTATATGCGTTTATTTCATATCGTTCAAAAAATGGTTATAGCAGTCATTCTAATGCTCGAAT
GATATCGACATTGCGTAAATTCTATGCTTGGCTTATCTCAACTGGTCAAACTAATAATAATCCTACAGCT
AAGCTAACATTACCAAAATTAGCCAAGAAGTTACCTAAAGATATGACAGAAACTGATGTTGAGAGATTGC
TTCAAGCTCCTGATATGACAGAGGATGTTGGTATTCGCGATAAAGCAATGCTTGAACTGATGTATGCTAC
AGGTTTACGTGTAAGTGAATTGGTCGGGCTTAATATTGATGATATCGATATCAATATTGGGGTAATTCAG
GTAATGGGTAAGGGTTCAAAAGAGCGTATAGTGCCAATAGGTGAGTATGCATTGGAGTATTTGCAAAAAT
ATTTTGCAGAAGCTCGCAGGAGTTTATCTGAAAATTTCAAAGAGAAAGCAGTTTTTATCAGTAAGCATGC
AAAAAGAATAACGCGTCAGTCTTTTTGGCACAGAATCAAAAACTATGCACTTATCGCTGGTATAAATACC
GATATTTCGCCTCATACCCTAAGACATGCATTTGCTACTCACTTACTCAATCATGGGGCTGATTTGAGAT
CGGTACAGCTATTGCTTGGACATAGTAATGTTTCAACAACAACTATTTATACACATATATCTCAAAATCG
CTTACAAGAGATTTATCAAAAACATCATCCAAGGGGATA
Protein Sequence 
>gi|56707324|ref|YP_169220.1| integrase/recombinase [Francisella tularensis subsp. tularensis SCHU S4] MSSAVDAFLDNLWLEHGLSQNTISSYRTDLKFLQNYFAKTDLISLDFEQLYAFISYRSKNGYSSHSNARMISTLRKFYAWLISTGQTNNNPTAKLTLPKLAKKLPKDMTETDVERLLQAPDMTEDVGIRDKAMLELMYATGLRVSELVGLNIDDIDINIGVIQVMGKGSKERIVPIGEYALEYLQKYFAEARRSLSENFKEKAVFISKHAKRITRQSFWHRIKNYALIAGINTDISPHTLRHAFATHLLNHGADLRSVQLLLGHSNVSTTTIYTHISQNRLQEIYQKHHPRG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: xerD mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG4974L, under L: Replication, recombination and repair
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].