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secA

Victor ID 703
Gene Name secA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3192077
NCBI Protein GI 56707883
Locus Tag FTT0769
Protein Accession YP_169779.1
Other Database IDs UniProtKB-ID: SECA_FRATT
UniRef100: UniRef100_Q14I65
UniRef90: UniRef90_B0TYK5
UniRef50: UniRef50_Q13U01
UniParc: UPI000049C397
EMBL: AJ749949
EMBL-CDS: CAG45402.1
RefSeq_NT: NC_006570.2
HSSP: P10408
GenomeReviews: AJ749949_GR
HOGENOM: HBG284200
OMA: GGMVLHD
ProtClustDB: PRK12904
Taxonomy ID 177416
Gene Starting Position 788287
Gene Ending Position 791007
Gene Strand (Orientation) +
Protein Name preprotein translocase subunit SecA
DNA Sequence 
>gi|56707187:788287-791007 Francisella tularensis subsp. tularensis Schu 4, complete genome
GATGTTAAGTTTAGTACAGAAAATAATAGGTAGTCGTAACGAAAGATTTATAAAAAAAGTTTCTAGAATA
GTTCAAAAAATTAACTCTTTAGAACCTGAGTTTGAGAAACTTAGTGATGAGCAATTAAAAGCAAAAACTT
TTGAATATCGCGAAAGACTTGCAAACGGTGAAATATTAGACAATCTTTTGCCAGAAGCTTTTGCAACCGT
TAGAGAAGCTGGAAAGCGTACTAAAAATATGCGTCATTATGATGTTCAGCTGATAGGTGGTATAGTTCTT
CATCAAGGTAAAGTTGCTGAGATGAGAACAGGTGAGGGTAAAACTTTAGTTGCCACATTACCAGCTTATC
TAAATGCTTTGACTGGTGATGGTGTACATGTAATTACAGTTAATGATTACCTTGCTAAGCGTGATGCTGA
GCTAATGAGTGATATTTACGAATTTTTGGGAATGTCTGTAGGTGTAATAGTTGCTGATTTAAATCCCCAG
CAACGTAAAGAAGCTTATGCATGTGATATCACTTATGGAACAAACAATGAATTTGGTTTTGATTATCTAA
GAGATAATATGGCTTATGAAAAAGAGCAGCAAGTTCAAAGAAGCCGTAACTATGTAATCATAGATGAGGT
TGACTCAATTTTGATTGATGAGGCTAGAACACCACTTATCATATCAGGTGCCTCAGATGATAGATCTGAG
ATGTATAACCTTTTCAATAGATTAGTTCCGTACTTAGAAAAGCAAGAAAAAGAAGAAGTTGAAAATGAAC
AAGAGCAAAGAGATTTTTATGTAGATGAAAAATCCAAAAATGCTTATCTAACTGAAAAAGGTTATGCAAA
AATTGAGAATATGCTCAAAAAAGAAGGTATTCTTGAAGAAGATGATAACCTTTATAGCCCTCACAATATT
ACAAAAATGCATTACTTAAATGCATGTCTAAGAGCTCATTCGTTGTATCAACTTAATATTGATTATATTG
TGAGAGATCAGGAAATAGTTATTATTGATGAAAGTACTGGTAGGGCAATGCCTGGTCGCAGATGGTCAGA
TGGTTTGCATCAGGCAATAGAGGCTAAAGAGGGCGTCAAAATTAATGCTGAAAATCAAACAATGGCATCT
ATTACCTTCCAAAATTTCTTTAAATTATATAACAAAATTGCTGGTATGACTGGTACTGCTGATACTGAGG
CATTTGAGCTTCATTCTATCTATGGTTTAGAGGTAATTATTATACCAACTAATAAACCGATGATTAGAAA
AGATCATCATGATGAGATATATGGTAGTGTAAGAGAGAAATTTGATGCTATAGTTGAGGATATTAAGGAG
AGAATTTCAAAAGGTCAGCCGGTACTAGTTGGTACAGCATCTATTGAAGCATCTGAAGTATTATCAACGT
TGTTGAAAAAGAAAAAAATCAGACATAATGTTTTGAACGCTAAACAACATGAGAAAGAAGCTAGTATTAT
TGCCATGGCTGGCTACCCAGATAATGTGACAATCGCAACGAATATGGCAGGTCGTGGTACAGACATTATT
TTAGGCGGTAATTTAGAGGTTGAAATAGCACAGCTTGAGGATCCTACACCAGAAGATATTGCTCAAATAA
AAGCAGAATGGTTAAAGCGTAATGAAGCTGTTAAGAAAGCTGGTGGACTATGTATCATTGGTTCAGAAAG
ACATGATTCCCGCAGGATCGATAATCAGCTAAGAGGTCGTGCTGCTCGTCAGGGTGATCCTGGTGAGAGT
AAATTCTATCTATCTATGGATGATAATCTTTTGCGAATTTTTGCTTCTCAACGTATGGCAGAAAGGGTTA
AAAAAGGTCTAAAAGGTGGTGAGTCACTAGCTTTTGGGTTTATGTCAAAAGTTATATCAAAAGCACAGGG
TAAGGTAGAGAGTTATCATTTTGATATCCGTAAGAATCTATTAGAGTATGACAATGTTGTTAATACACAA
CGTAAAGTTATTTATGAGCAAAGACAGTCATTCTTAGAAGCTGAAGATGTTAGTGATATTCTTGCTGATA
TTCGTATTGATGTGGCTGAGCAGTTGTTTCATGATTATGTACCTGCTGGTTCCATGCATGAACTGTGGGA
TCTTGAAGGCTTAGAGAAGGCACTTAAATCTGACTTTATGATTGAGCTTGATCTACAGAAGCTTTATGAA
GAAGATGATAGCTTAGGAGAAGAAGATCTTAAGAGGCTAGTAAGAGAAGCTATAGAAATTGAATTTGTTG
AAAAAACCAAGAATTTAGATTCAGGCGCTGTGAGACAATTTGAGAAATTCTCATTATTACAATCTCTTGA
TACTCATTGGCGTGAGCATTTGAGTTCAATAGACCATTTACGTAATAGTATAAATCTACGTGGTTATGCT
CAAAAAGATCCAAAAAATGAGTATAAAAAAGAAGCCTTTGAGCTTTTCTCAACTATGCTAGATAATTTCA
AATATGAGGTTATATCTTCACTTGCTAAGATTAGAATTGCTACTGAAGAAGAAACGCAAAGAGCTCAGCA
AGAATGGCAAGAATCTATGAGTGATATTAAAGCTGAGCATGAAAGTGTGATTGATAACAATCAAAGACAT
GATGAGGATGAGCAAGAAGAGGCTCCAAAAGTTAAGCAAGTTAGAAGAGAAGGTCCAAAAGTTAAAAGAA
ATGATCCATGTCCTTGTGGCTCAGGTAAGAAATATAAACAGTGTCATAGTAAGGTTGAGTA
Protein Sequence 
>gi|56707883|ref|YP_169779.1| preprotein translocase subunit SecA [Francisella tularensis subsp. tularensis SCHU S4] MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMRTGEGKTLVATLPAYLNALTGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADLNPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDRSEMYNLFNRLVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQLNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNAKQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQRMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVPAGSMHELWDLEGLEKALKSDFMIELDLQKLYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVKQVRREGPKVKRNDPCPCGSGKKYKQCHSKVE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a secA mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0653U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].