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wbtA

Victor ID 688
Gene Name wbtA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191939
NCBI Protein GI 56708505
Locus Tag FTT1464c
Protein Accession YP_170401.1
Other Database IDs UniProtKB-ID: Q79RD8_FRATT
UniRef100: UniRef100_Q14GE4
UniRef90: UniRef90_A7NAU9
UniRef50: UniRef50_B0TXL0
UniParc: UPI000034E327
EMBL: AY101577
EMBL: AJ749949
EMBL-CDS: AAS60264.1
EMBL-CDS: CAG46097.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG429349
OMA: SHRRIME
ProtClustDB: CLSK986376
Taxonomy ID 177416
Gene Starting Position 1514714
Gene Ending Position 1516450
Gene Strand (Orientation) -
Protein Name dTDP-glucose 4,6-dehydratase
DNA Sequence 
>gi|56707187:1514714-1516450 Francisella tularensis subsp. tularensis Schu 4, complete genome
ACTACCCATTCAATCTATGTTCAAATTCCGGAACAATTTTCTTTAATATCACAAGCTGATCAACATCATC
CTTGATCAACGATTCAATATCTTGGTTTAGAGTATTAATATCGTAAAAAGTCCTTCTACCAATAAAAATA
TCTTTATAGTCGGTACTAACATCATCTTCCTCTATCAAAAGCTCTTCGTAAAGTTTCTCTCCTGGACGCA
AACCAACTATTTTAATATCAATATCACCTCTACCAGAAAGTCTAATAAATTGTTTAGCAAGATCAATAAT
CTTGACAGGTTGCCCCATATCTAAGACAAAGACCTCTGAATTTTTTGCAATAGCACCAGCTTGTAGGACC
AGTTCACAAGCTTCTGGTATCAACATAAAATAACGTGTAATTTCAGGATGAGTAACTGTAACAGGACCAC
CTTTTCTTATTTGCTCTTCAAATTTTGGAATCACACTGCCACTACTACCAAGCACATTACCAAAACGCAC
TGCAGCAAGCTTGGTATTTTTGGGATCAACATTCTGTAAATACAGCTCACAAACTCTCTTGGTAGCCCCC
ATAACATTCGTTGGTCGCACTGCTTTATCAGTGGAAATCAATATAAATGACTCAACACCAGCTTCTATAG
CCAGATCTATAGCATTCTTAGTACCTAAGATATTATTTCTAATTGCTCTAGAGATATTCTCCTCAACTAA
GGGAACATGCTTGTAGGCAGCAGCATGAAATACTATATTTGGAGTATACTTTTGAAAAACCTCAGCCAAT
GCTTTTCTATCACAAACAGAACATAGCACACTATTGATATTAAAATGACTACACTCCTCAGTAATTTTAT
ATAAGTTAAACTCACTATGATCAACCAATATCAACTCTTTTGCCTGATACTTGATACATTGATGTACTAT
TTCAGAACCTATACTACCTCCAGCTCCTGTGACTAGCACCACCTTATTTTTGATAAAATTAGAGATAGAT
TCTTTATCTAAACTCTTAGTATCACGCGCTAATAGATCATAGAGTGAAACAGGCTTCAACTGTGACATAA
AATTCTCATCTTGAAGAATTTCCTCAAGAGGCGGCATAATTCTAATCTGATTAAAATCCTTTTCAAATTC
TTTATATATATTTTTGACTACTTGGTTTGCATTTCTTGGCAATGCAATAACCAAAAGGTCAAATCTACTA
GATAGCAATAGTTTTGTTAATTCAGCTTTAGATAGAACCTTTTTACTATCAATACTTCTTTTTTGTAAAG
TTTCATTGTCATCAACAAAACATTTGATGCGATAACCAGCAGAAGCAAGTTCTTGAGCAATCTTTGTTCC
TGCAGCACCTGCACCATAAATAACCGCAGTTTTACTTTTATCCACTGATCCTCTGTTCATCAAATACCAA
TAAAAGTAGACACTTAAACTGATCAAAAAAACATAAAATAAAAACTCAGAGAATATCAACGAAAAAGTGA
CTTTGCCATAAAAAAATAATGCCACTATGAAAAATACTGGCAAATTAATAAAAGCCTTACGTAAAAAAGT
TTTTTGAGTCGACTTACGCCAACTAGCCATATAATCTCTAAGTAGTAAAAAAGATGACAAGCATCTCAGC
AAAACTAATGCAAGTAAAAAATGTAAATTAACATCTTGCTTGAAAATATAGAAAGTCCAATTAACAGTAA
TAATAGTTAAAACTATTATTACCACGAAATTAAGCGTTCTATTATCGTAGAAAGACA
Protein Sequence 
>gi|56708505|ref|YP_170401.1| dTDP-glucose 4,6-dehydratase [Francisella tularensis subsp. tularensis SCHU S4] MSFYDNRTLNFVVIIVLTIITVNWTFYIFKQDVNLHFLLALVLLRCLSSFLLLRDYMASWRKSTQKTFLRKAFINLPVFFIVALFFYGKVTFSLIFSEFLFYVFLISLSVYFYWYLMNRGSVDKSKTAVIYGAGAAGTKIAQELASAGYRIKCFVDDNETLQKRSIDSKKVLSKAELTKLLLSSRFDLLVIALPRNANQVVKNIYKEFEKDFNQIRIMPPLEEILQDENFMSQLKPVSLYDLLARDTKSLDKESISNFIKNKVVLVTGAGGSIGSEIVHQCIKYQAKELILVDHSEFNLYKITEECSHFNINSVLCSVCDRKALAEVFQKYTPNIVFHAAAYKHVPLVEENISRAIRNNILGTKNAIDLAIEAGVESFILISTDKAVRPTNVMGATKRVCELYLQNVDPKNTKLAAVRFGNVLGSSGSVIPKFEEQIRKGGPVTVTHPEITRYFMLIPEACELVLQAGAIAKNSEVFVLDMGQPVKIIDLAKQFIRLSGRGDIDIKIVGLRPGEKLYEELLIEEDDVSTDYKDIFIGRRTFYDINTLNQDIESLIKDDVDQLVILKKIVPEFEHRLNG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a wbtA mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG1086MG, under M: Cell wall/membrane/envelope biogenesis; G: Carbohydrate transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].