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uvrA

Victor ID 683
Gene Name uvrA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191913
NCBI Protein GI 56708369
Locus Tag FTT1312c
Protein Accession YP_170265.1
Other Database IDs UniProtKB-ID: Q5NFC7_FRATT
UniRef100: UniRef100_Q14GT0
UniRef90: UniRef90_A0Q5P3
UniRef50: UniRef50_P44410
UniParc: UPI000049C4F5
EMBL: AJ749949
EMBL-CDS: CAG45945.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG284763
OMA: GAIKGWD
ProtClustDB: CLSK934958
Taxonomy ID 177416
Gene Starting Position 1336515
Gene Ending Position 1339337
Gene Strand (Orientation) -
Protein Name DNA excision repair enzyme, subunit A (UvrABC system protein A), ABC transporter, ATP-binding protein
DNA Sequence 
>gi|56707187:1336515-1339337 Francisella tularensis subsp. tularensis Schu 4, complete genome
GCTAAAGTAAATCTTTAAGATACTTACCAGTGTATGATTTTTTACAGTTAATTATATCCTCTGGAGTTCC
CTCAAAAATTATCTGCCCTCCTTTACTACCACCTTCTGGACCTAAATCAACAAGCCAATCTGCCATTTTT
ATCACATCTAAATTATGTTCAATAATTACAACAGTATTACCTTTATCACGCAGATCCATGATTACTTTTA
GAAGTTGATGAATATCATAAAAATGTAAACCAGTGGTCGGCTCATCCAATATATATAAGGTTTTACCAGT
TGAACGTTTTGATAGCTCTTTTGCTAATTTAACTCTTTGTGCTTCACCACCAGAAAGAGTAGTAGCACTT
TGTCCTAGCTTAATATACGACAGTCCAACGTTCATCAAAGCTTCCAGCTTAGTCTTAATACTTGGTACTG
CATCATAAAATTCAAGTGCCTCTTCGACAGTCATCTCCAATACTTCGTAAATATTTTTACCTTTGTATTG
CACCGCTAAAGTTTCGCGATTATAACGCTTGCCTTGACAAACATCACAAGCAACATAAACATCTGCGAGA
AAATGCATCTCTACCTTTATAACGCCATCACCTTGACATGCTTCACATCTTCCGCCACGAACATTAAAGC
TAAATCTTCCAGCACTATATCCTCTAGCTCGAGCTTCTGATGTTGCAGCAAATAATTCGCGTATGGGTGT
AAACACTCCCGTATAAGTTGCTGGATTAGAGCGTGGAGTTCTACCTATTGGTGATTGATCAATATCTATA
ACCTTATCAAGGTGATTAAAACCTTTATGTGAGGTATACTGCATTGGTACTAAAATACTTCTGTTTAGTA
AACGAGAAGCCAAAGGATATAAAGTTCTATTTATCAGCGTTGATTTACCTGACCCTGAGACACCTGTCAC
ACATGTCAATGCCCCTAGAGGGATTTTAAGATTATCTCCTTGAAGATTATTACCGACCGCACCACTTATT
TCTAGATAACGACTTTTCCTAGCTTTTAGCCTAGTTTTTGGAACTTCAATTTTTCTACGACCACTTAAAT
AATCTGCAGTTAAAGACTTTTTACTCTTGAGTATCGTTTCATAACCACCAGCAGCAACTACCTCACCACC
ATGTACACCTGCCATTGGTCCCATATCGATTATATAATCTGCTTGACGAATCGCATCCTCATCATGCTCA
ACAACGATTACAGTATTACCTAGATTTTTAAGGTTATGTAAAGCATCAAGCAAACGTTGATTATCCCTTT
GATGAAGACCGATCGATGGCTCATCTAATATATACATCACACCAACAAGACCAGCGCCTATCTGACTTGC
TAAACGAATACGCTGAGCCTCACCACCAGAGAGAGTATCAGCTTGCCTTGCTAAGCTTAAATACTCTAGC
CCAACATTTGCTAAAAACTCTACTCTTAGTTTAATCTCTTTGAGTAAATTCTCTGCGATAACTTGTTGTT
GACCGACAAACTTTAGACTATCCAACCACTTTAATAACTCATCAATAGGCAAAGCACAAACATCAGCTAT
ATTTTTATCAGCAATAAATATATTGCGTGCATATTCATTAATTCTCGCACCATTACAAGACTTACATTCA
AGGTTACTCATAAGCTCATAAAGATCTTTTTTAACCATATCTGAGTCAGACTCATAATATCTGCGTTCAA
AATGAGGTATAACACCCTCAAAAGGTTTAATACGAGTTTGTCTACCTCCTCTGATAGAATCAACACTCAT
TACGATAGCCTCGTCACCAGAACCATATAAGATTATTTCTTGAATTCTTTTAGGTAGCTTCTCAAACCGC
TCATCTAAAGAAAATTTGTAGTGTGTTGCTAAAGACTCTAATTGAGAAAAATAGTATTGATTAGTTTTAT
TCCACTTAACTATAGCTCCATGCTTAAGTGAAATTGATGGATCTATAACAACCTTTTGCTCATCAAAAAA
TTCTTTAACACCAAGTCCATCACAACTGCTACAAGCCCCCAACGGACTGTTAAAAGAAAAAATTCTTGGT
GATAATTCTTTAAGTGCAAAATCACACAAAGGACAAGCATGCTTTGATGAAAATAAGATATCATCGCCAG
TTTGATTTGCCATATCTGCTAATTTAACAATACCATTACCAAGGTCTAAAGCTGTTTCTATTGATTCAGC
GATACGTTGTTCGTTCTCTTTTTTGGGTTTAAATCTATCAATAACGACATCAATATTATGTTTTTTATAA
CGATCCAATTCAGGATAATCTTCATCAAGTTTATAAAACTCGTCATTTATACGCACACGAACATATCCTT
GTGCTAATATCTTATCTAATAAAGTATGGTGTGTACCTTTTTTTTGAGAAATAATTGGTGCTAGTATCAT
CAATCTTGAATCTTCATCAAATTCCAAAATTTTATCAACCATTTGGCTGATAGTTTGAGCCTTCAATTCT
ATTTGATGTATCGGACATTTTGGTGTACCAGCTCGTGCAAAAAACACTCGCAGATAATCATATATCTCTG
TTACAGTTCCAACTGTAGATCTTGGATTATGAGATGTTGTTTTTTGATCTATTGAAATAGCTGGAGAAAG
GCCTTCTATATGCTCAACATCTGGTTTATCCATCATCGACAAAAACTGTCTTGCATATGAAGATAATGAC
TCAACATACCTTCTTTGCCCTTCAGCATATAGAGTATCAAAAGCTAATGAAGATTTACCAGAGCCACTTA
ATCCTGTGATAACAGTTAGCTTATCCCGTGGTATCTCAACATCAATATTTTTTAGGTTGTGGGTTTTTGC
GCCCTTGACGATAATTTTTTTCA
Protein Sequence 
>gi|56708369|ref|YP_170265.1| DNA excision repair protein subunit A [Francisella tularensis subsp. tularensis SCHU S4] MKKIIVKGAKTHNLKNIDVEIPRDKLTVITGLSGSGKSSLAFDTLYAEGQRRYVESLSSYARQFLSMMDKPDVEHIEGLSPAISIDQKTTSHNPRSTVGTVTEIYDYLRVFFARAGTPKCPIHQIELKAQTISQMVDKILEFDEDSRLMILAPIISQKKGTHHTLLDKILAQGYVRVRINDEFYKLDEDYPELDRYKKHNIDVVIDRFKPKKENEQRIAESIETALDLGNGIVKLADMANQTGDDILFSSKHACPLCDFALKELSPRIFSFNSPLGACSSCDGLGVKEFFDEQKVVIDPSISLKHGAIVKWNKTNQYYFSQLESLATHYKFSLDERFEKLPKRIQEIILYGSGDEAIVMSVDSIRGGRQTRIKPFEGVIPHFERRYYESDSDMVKKDLYELMSNLECKSCNGARINEYARNIFIADKNIADVCALPIDELLKWLDSLKFVGQQQVIAENLLKEIKLRVEFLANVGLEYLSLARQADTLSGGEAQRIRLASQIGAGLVGVMYILDEPSIGLHQRDNQRLLDALHNLKNLGNTVIVVEHDEDAIRQADYIIDMGPMAGVHGGEVVAAGGYETILKSKKSLTADYLSGRRKIEVPKTRLKARKSRYLEISGAVGNNLQGDNLKIPLGALTCVTGVSGSGKSTLINRTLYPLASRLLNRSILVPMQYTSHKGFNHLDKVIDIDQSPIGRTPRSNPATYTGVFTPIRELFAATSEARARGYSAGRFSFNVRGGRCEACQGDGVIKVEMHFLADVYVACDVCQGKRYNRETLAVQYKGKNIYEVLEMTVEEALEFYDAVPSIKTKLEALMNVGLSYIKLGQSATTLSGGEAQRVKLAKELSKRSTGKTLYILDEPTTGLHFYDIHQLLKVIMDLRDKGNTVVIIEHNLDVIKMADWLVDLGPEGGSKGGQIIFEGTPEDIINCKKSYTGKYLKDLL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a uvrA mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0178L, under L: Replication, recombination and repair
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].