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cphA

Victor ID 682
Gene Name cphA
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191888
NCBI Protein GI 56708207
Locus Tag FTT1130c
Protein Accession YP_170103.1
Other Database IDs UniProtKB-ID: Q5NFT9_FRATT
UniRef100: UniRef100_B2SDD6
UniRef90: UniRef90_Q0BMD4
UniRef50: UniRef50_Q0BMD4
UniParc: UPI000049C483
EMBL: AJ749949
EMBL-CDS: CAG45763.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG288839
OMA: APGLRMH
ProtClustDB: PRK14016
Taxonomy ID 177416
Gene Starting Position 1140631
Gene Ending Position 1143453
Gene Strand (Orientation) -
Protein Name cyanophycin synthetase
DNA Sequence 
>gi|56707187:1140631-1143453 Francisella tularensis subsp. tularensis Schu 4, complete genome
TTTAATCATTATCTTCTTCATGATACACCACTCTAACACCACTATCATCAGAAATTATCCCAGCTTTTAT
AACTTGTGATATTTCTTCTGATAAGCTAGGGTCTTGAGCTATTACAGAAGCCGAAAACATTTCTTGTTTC
TCAAGTTTTTTATCTTTACCATCAAACTCTTGATCCTTGTTAAAGTATATAATCTGCTTCCAAGTTCTTT
TTAGCTTATCAGCAAATATTACTACTAAGTCGCCTTCTTCTGCCATATTCAGTGCTGCATCCACTGCTTC
TTTTTCACTTTCTATAATTTCAATATTATCAGCAGATATACCTGCTTCAATTAATGCTTCTTTTAATATT
CTTGGCACTTCATCTGGTGCTCTACCTCTAGTATCATCATCACGCTTACAAATAAAGTAGTCATAATAAG
GTGCCGCAGTTTTTGCTAACTCGGCAATATCCTCATCTCTTCTATCTCCAGGAGAAGCTAGTACGCATAT
TTTTTTGCCAGCGAATTCCATATTCATAATCATTTGACTAACTAGTTTGATAGCAGCTGGATTGTGTCCA
TAATCCATTAGTACTTTAAATGGATGTTCTTCAAACCAATTCATACGTCCTGGGGCTTGATAGAATGATG
TTACGAAAGTTCTTAAACCATCTCGCATATCATCTAAGCTCATTCCCATACTATAGCATATAGCTATTGC
AAACATTGAGTTTTGAACATTATGAATAGCTTTACCTTCCATAGTTGCTGGTATTAAGTGTGTCCATAAT
ACTGGTATATGGATATGATTATCAAAGATTGTAATCATATCTCCATTTACACCCTTCTCGATAATACATG
CCTTACCGCCTGCACGTATATGCTGTTTAACTAACGCATGCTCTGGGTTCATTGTCACATAGAAAATATG
TTTAGCTGTAACTTTAGCTGACATTTTCAAGACATTAGGGTCATCTGCATTTAAAACTGCAACATCTTTT
GCAGCTTCAACAACTATACTTTTCACTTTAGCTAAGTCTTCTAGAGTGTTAATACCTTTCAAGCCTAAAT
GATCAGCAGAAATGTTTAAGCAAGCTCCAACATTACAATAGTCATAACCTAGACCACTTCTTAATAGTCC
GCCTCTTGCTGTTTCCAAAATAGCCATTTCTACAGATGGATCTTTCAAAACCATTTGCGCTGAAGCTGGT
CCTGTGGTATCTCCCGCTACTGTAAGTTTACCATTTATGTATACACCATCAGTAGTTGTTAATCCAACAA
CTTTACCAGCATTTTTCCACATATGTGCTACCATACGTGAAGTTGTAGTTTTACCATTAGTACCTGTGAT
TGCAGCAATAGGAATTCTAGCATTACCGTACTCTCTAGGAATAAGCATATCAATAACTGCACCAGCAACG
TCTCTTGGCTTACCTTCACTTGGTGCCACATGCATTCTAAATCCTGGCGCGGCATTACATTCACAAATTG
CTCCACCGATATCATGATATGATTGTGAAATATCATCAATAAGGAAATCCACACCACCAACATCTAAGCC
AATTGCCTTAATAGCTCTCTCTGCCATATCTCTGTTATCTGGATGAACAATATCTGTCACATCTATAGCT
GTACCACCAGTTGATAAATTAGCTGTAGATCTTAGGTAAAATACTTCGCCATCTTTAAGAATAGTATTCT
CATCATAACCAGCTGCTCTTAGCAATGTTCTTGCCTGATAATCTAACTCTAACTTTGTTAGAACTTTCTC
ATGACCGATACCTCTACGTGGATCTTGGTTAACTATCTCAACTAGTTCTGCAATTGTATGCTTACCATCA
CCAACTACATGACCAGGCACTCTCTTTGCAACAGCTATAAGCTTACCATCAACGACAAGCATCCTATGGT
CAAAGCCTATTACATATTGTTCTAATAATACATAACGCGAAACTTTATTAGCCTCAACAAATGCTTCTTT
TATTTCTTCAATTGTCTTAAGATTAATTGAAATACCTCTACCATGGTTACCGTCTAATGGTTTAACAACT
AAAGGAAAACCTAAAATTTTAGCTGCTCTTACAGCGCCTTCTTCTGTTGTAACCATTCTTTGCTTTGGTA
CAGGTAAGCCTAAACTACTCAATATCGTGTTTGTCTGCTCTTTATCACATGATAGATCAACAGCAATACT
AGTTGTTTTACCAGTAATCGTTGCTCTAATTCTTTGTTGATACTTACCATAACCAAACTGTACTAAAGAT
TGATCGTTTAGACGGATATATGGAATATCTCTTTTCTTTGCGGCTTCTACCAATGAAGCTGTACTAGGTC
CAAATTCTTTACTTTGAGCAAATTTTATAAATCTAACCTTTTCATACTCAAAGTCAAAATCTTCATTTGC
AAATTCTACTTGTTTTTTTAGGTTCTCTGGCAATATAGATATCAATAAGTCTCTAGCTAATTCCATAGCT
CTTAGACCAACATCCTTTTGCTTATACTCATAAACCATATTATAATGACCTACTTCACCCGTTGATCTAG
TACGTCCAAATGTTACATCACTACCAGCCATACTTTGAAGCTCTAAAATCACATGCTCCCAAATATGTCC
CATCCAAGTACCTTCATCCTCTCTTAATCTACGGATGAATCCTCCTTTTTCTCTATAAGAACAGCCATGC
TCTTGTAATCCTGGCAAGCTCTCCACCAGTTGATCTATAAACTTGTTTCCAATCTTTGCAGAAGGCCAAT
TTTCTAGCACTCCTAGATCAATCTCATGTCTTATAACAGGAAAGTTAGCATAAATGTTAGGTCCCACATA
AACATTAGTAGATAGTATTTTCA
Protein Sequence 
>gi|56708207|ref|YP_170103.1| cyanophycin synthetase [Francisella tularensis subsp. tularensis SCHU S4] MKILSTNVYVGPNIYANFPVIRHEIDLGVLENWPSAKIGNKFIDQLVESLPGLQEHGCSYREKGGFIRRLREDEGTWMGHIWEHVILELQSMAGSDVTFGRTRSTGEVGHYNMVYEYKQKDVGLRAMELARDLLISILPENLKKQVEFANEDFDFEYEKVRFIKFAQSKEFGPSTASLVEAAKKRDIPYIRLNDQSLVQFGYGKYQQRIRATITGKTTSIAVDLSCDKEQTNTILSSLGLPVPKQRMVTTEEGAVRAAKILGFPLVVKPLDGNHGRGISINLKTIEEIKEAFVEANKVSRYVLLEQYVIGFDHRMLVVDGKLIAVAKRVPGHVVGDGKHTIAELVEIVNQDPRRGIGHEKVLTKLELDYQARTLLRAAGYDENTILKDGEVFYLRSTANLSTGGTAIDVTDIVHPDNRDMAERAIKAIGLDVGGVDFLIDDISQSYHDIGGAICECNAAPGFRMHVAPSEGKPRDVAGAVIDMLIPREYGNARIPIAAITGTNGKTTTSRMVAHMWKNAGKVVGLTTTDGVYINGKLTVAGDTTGPASAQMVLKDPSVEMAILETARGGLLRSGLGYDYCNVGACLNISADHLGLKGINTLEDLAKVKSIVVEAAKDVAVLNADDPNVLKMSAKVTAKHIFYVTMNPEHALVKQHIRAGGKACIIEKGVNGDMITIFDNHIHIPVLWTHLIPATMEGKAIHNVQNSMFAIAICYSMGMSLDDMRDGLRTFVTSFYQAPGRMNWFEEHPFKVLMDYGHNPAAIKLVSQMIMNMEFAGKKICVLASPGDRRDEDIAELAKTAAPYYDYFICKRDDDTRGRAPDEVPRILKEALIEAGISADNIEIIESEKEAVDAALNMAEEGDLVVIFADKLKRTWKQIIYFNKDQEFDGKDKKLEKQEMFSASVIAQDPSLSEEISQVIKAGIISDDSGVRVVYHEEDND
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cphA mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0769M, under M: Cell wall/membrane/envelope biogenesis
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].