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fadB/acbP

Victor ID 679
Gene Name fadB/acbP
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191871
NCBI Protein GI 56708564
Locus Tag FTT1530
Protein Accession YP_170460.1
Other Database IDs UniProtKB-ID: Q5NET2_FRATT
UniRef100: UniRef100_Q14G85
UniRef90: UniRef90_A0Q7U1
UniRef50: UniRef50_B2SEN4
UniParc: UPI000049C576
EMBL: AJ749949
EMBL-CDS: CAG46163.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG729334
OMA: FRTLDVV
ProtClustDB: CLSK896566
Taxonomy ID 177416
Gene Starting Position 1589550
Gene Ending Position 1592246
Gene Strand (Orientation) +
Protein Name fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein
DNA Sequence 
>gi|56707187:1589550-1592246 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGACAGAGTTAGAGAAAAAGTTTGAAGAAATGCTGATAGCCGTTCGTGATGCGACTATTGATTTCAAA
CCTGATAATAGCCAAAAGTTAAAACTTTACGCTTTTTATAAACAAGTAAAAGAAGGTGATAATAATACAA
AAAAACCTTCTGCTTTGAAAATGGTTGAACGCGCTAAGTGGATGGCTTGGGATGCGATTAAAGGCATGTC
AAAAGAAGATGCTATGCGTGGTTATCTAAGGGTTTTTGGCGAGGAGTATCTTCCGGCGGGAGAAAGTGAT
AATGATAGTCCTAGTAGCACTATCGCAAGTAAATTAGAACCTGTAGAAAGTAAATCACAGCGTAAAGCTA
TTGATAAAATTGCAGTTCTTGGTGCTGGAACTATGGGAGCACAAATTGCTGCTCACTTTGCAAATGCTAA
ATTCCCTGTTGTTTTATTTGATTTAAAATCCCAACAAGGTAGTGCTAATGTTATTATTGAAGATTCTCTA
GCCAAGCTCACCAAACTTAATCCTGCCCCTTTTGGTTCAAAAGATTCAATAAAATACATTACTCCAGCAA
ATTATGAAGATAATCTTGAGCTTCTAGCAGACTGTGATTTAATCATAGAAGCAGTAGCCGAACGTATAGA
TATCAAAGAAAGCCTCTACACAAAAATCTCTAGTCATATCAAAGAAAATGCAATTTTAGCATCAAATACT
TCTGGCTTGAGTATCACAAAACTAGCACAAGTATTACCAGAGAATCTCAAAGTTAATTTCTGTGGTGTAC
ACTTTTTTAACCCACCGCGCTATATGCCTTTAGTTGAGCTAATCCCTCATGCAGATACTAATTCTGAAAT
TTTGGATAAACTAGAAACATTCTTAGTTGAAAAACTTGGTAAAAGTATAATTCGCGCAAAAGATACACCA
AATTTTATCGCTAATAGATTAGGTGTCTTTTCAATGCTAGTAACTTGTTACTATACAGAGCAGATGAGTA
TTCCTTTAGAAGTTGTTGATGAACTTACAGGCAAAAAACTAGGTCGTGCAAAAAGTGCTACTTATAGAAC
TGCTGATTTGGTTGGTTTAGATGTGTTATCTCATGTTGTTGAAACTATGAAAGATAATCTCGAAGATGGT
TGGCAAAAGCTATACAACACACCCAACTGGATTCAGAATCTAATCAATAATGGTTCACTTGGTCAAAAGA
CTAAAAAAGGCTTATATATCAAAGCATCTGATGGTATCAAAGTACTTGACTTAGGTACTAATGAATATCG
CCCTGCTGATAAAAAAGCTGATAAAGAAATCTTAGATATACTAGCTGAGAGAGATTGGAGCAAAAAACTG
GAAGGTCTGCGTAATAGCGATAATCATCAAGCTCAATTCTTATGGGCAACTTTTAGAGAGATGTTCTTAT
ATGCTGCTCATCTAGTTGGAGATATCTCAAATTTCCCTAAAGACATGGATTTAGCAATTCGTTGGGGATT
TGGTTGGAAACAAGGTATTTTCGAGATATGGCAACTTGCTGGGTGGCATAAAGTAGCTAGCTGGCTAAAA
GACGATATTTCAACTGGTAAAGCATTATCAACAAATACTCTACCTAGCTGGATTGATACTCTTGATATCA
GTGTTTATCAAAATAATAAAGAGTTTAGCTATAAGGATAAAGAGCTAATATCTCGTGATAGCTTAGATGT
TTATAAACGTCAACTATTCGCTGATAATATAGTTGAACATACTAGCACTTTAGCGACACAAACACTTTAT
GAAAATGATGGTGTCAAACTATGGCAGATTGATGACTATAGCAATATCGGAATACTCTCATTTAAGAGTA
AGATGTGTGCTATTGGTGATGATGTTTTAGATGGTATATCTGAGTCTATCAACTATGCTGAAGAAAAGCT
TGATGGTCTTGTTATTTGGCAAGAGCAAGATGTATTTTCGGTAGGTGCCAACTTAGAGGAATTTGGTATC
AAATTTGCAATGAACGGCGAAGCAGCTATCGAAGAGGTAATCCGTAAAGGTCATAGCATTATCAGTAAAA
AATTACGCTATAGCAAAATACCTGTTGTTGCAGCTGTCAAAGGCTTTGCTTTTGGTGGTGGCTGTGAAAC
AATCTTACATAGTGATGCTGCTGTTGCTGCGTATGAAAGCTATATTGGCCTTGTTGAAGCTGCTGTAGGA
ATTATCCCTGGTTGGGGCGGCTCAAAAGAAATGGCAGTTAGAGCATCTCAAGCTCAAGATCACTGGAAAG
ACTTTGAGCGTCGCTATAAGAACCTTGCTCTTGCACAAGTGGCTAAAAGTGCTTATGAAGCCAAAGAAAT
GGGCTTTTTGCGTGATGATGATATAGTAGTAATGAATACTAAAGAGATCCTACTTGTAGCAATTAAGAAA
GCTCAACTTATGGCTCTAGCTGGTTATCAACCACCTCTGAAACAAAAAGTCCCAGTATTTGGTGAAACTG
GTATTGCTACAATTAAAGCCTTACTAGTAAATATGCGCGATGGTAATCAGATATCTGAACATGATTATAA
GATTGCAGTAAATTTAGCAGATACTATGTGTGGTGGTCAGATAGAAAAAGATACTGAAGTTTCTGAAGAT
TGGCTACTCGAAAGAGAGCTGATAAACTTCAAAGAACTTGCGATATCTGAGAAAACAGAAGCTAGAATGA
AATATATGCTAGAAACTGGCAAACCACTAAGAAATTA
Protein Sequence 
>gi|56708564|ref|YP_170460.1| bifunctional 3-hydroxacyl-CoA dehydrogenase/acyl-CoA-binding protein [Francisella tularensis subsp. tularensis SCHU S4] MTELEKKFEEMLIAVRDATIDFKPDNSQKLKLYAFYKQVKEGDNNTKKPSALKMVERAKWMAWDAIKGMSKEDAMRGYLRVFGEEYLPAGESDNDSPSSTIASKLEPVESKSQRKAIDKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQGSANVIIEDSLAKLTKLNPAPFGSKDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTSGLSITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTNSEILDKLETFLVEKLGKSIIRAKDTPNFIANRLGVFSMLVTCYYTEQMSIPLEVVDELTGKKLGRAKSATYRTADLVGLDVLSHVVETMKDNLEDGWQKLYNTPNWIQNLINNGSLGQKTKKGLYIKASDGIKVLDLGTNEYRPADKKADKEILDILAERDWSKKLEGLRNSDNHQAQFLWATFREMFLYAAHLVGDISNFPKDMDLAIRWGFGWKQGIFEIWQLAGWHKVASWLKDDISTGKALSTNTLPSWIDTLDISVYQNNKEFSYKDKELISRDSLDVYKRQLFADNIVEHTSTLATQTLYENDGVKLWQIDDYSNIGILSFKSKMCAIGDDVLDGISESINYAEEKLDGLVIWQEQDVFSVGANLEEFGIKFAMNGEAAIEEVIRKGHSIISKKLRYSKIPVVAAVKGFAFGGGCETILHSDAAVAAYESYIGLVEAAVGIIPGWGGSKEMAVRASQAQDHWKDFERRYKNLALAQVAKSAYEAKEMGFLRDDDIVVMNTKEILLVAIKKAQLMALAGYQPPLKQKVPVFGETGIATIKALLVNMRDGNQISEHDYKIAVNLADTMCGGQIEKDTEVSEDWLLERELINFKELAISEKTEARMKYMLETGKPLRN
Molecule Role Virulence factor
Molecule Role Annotation MUTATIONO: a fadB/acbP mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG1250I, under I: Lipid transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].