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lpxB

Victor ID 667
Gene Name lpxB
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191793
NCBI Protein GI 56708594
Locus Tag FTT1568c
Protein Accession YP_170490.1
Other Database IDs UniProtKB-ID: LPXB_FRATT
UniRef100: UniRef100_Q14G55
UniRef90: UniRef90_Q14G55
UniRef50: UniRef50_Q14G55
UniParc: UPI000049C58D
EMBL: AJ749949
EMBL-CDS: CAG46201.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG584837
OMA: DFTHRVA
ProtClustDB: CLSK935090
Taxonomy ID 177416
Gene Starting Position 1629651
Gene Ending Position 1630793
Gene Strand (Orientation) -
Protein Name Lipid-A-disaccharide synthase
DNA Sequence 
>gi|56707187:1629651-1630793 Francisella tularensis subsp. tularensis Schu 4, complete genome
ATTAAGATTTTTCTATCATAGTATCTAATACTTGAATGATCTTACTCTCAGTATCGATAACCATTTCTTT
GTGAATTTTTTCAAATTCTTCTACTATATAATCATTACGCCGCTTATCATCAAACAACCTTTTTAACTCG
CTAAATAAATTATCTACTGTACAGTCTTCTTGTATTAATTCTTTGATAATTTCATTTTTATGCAAAATAT
TAGGGAAAGCCCAATAACTATGATTACCAATAAGCATCCTACCAATTAAAGCCGATAGCCATGATAGTTT
ATAGCCTACAACCATAGGTAATTTGCATAACATAGCCTCCAATGTAGCTGTTCCTGATGCCAATAAACTT
AAATCAGATGCTTTTAAAACATCATGTGAATTCGTTTCAAAAACTTCGATACCTAAACTATCAATTTGTT
CTTTATATTTAGCAAATAATGGTTTTAATGATGGCTTAGCTAAGGGCATAATCGCTTTAAATTTATATCC
AGCATCTACCAATTTTTGTAATGCTAACAAAAATAGTGGCAACAATCTTGAAACTTCTGTCGTACGACTT
CCTGGTAAAACTGATAATATTGGTAAAGAACTACCTTTTAATCCAAGTTTATCTCTATATTTAGCTCGGT
CAATATGTATTGGAATATTCTTCGCTAATGGATGACCAACATATATAGCTTCAAATTTATGTCTATTTTT
ATAGTATTCAGTTTCAAAAGGTAAAATTGCTAATATTTTATCAGTTGCTTTACGTATTTTTTTTATACGG
TATTCACGCCAAACCCATATTTTAGGACTTACATAATGTATAGTTTTGATACCCGCAGATCTTAATTCTT
TTTCAACTGTAAGATTAAAATCAGGAGCATCTATGCCTATAAATATATCAGGTTTATTTTGCTTAAAATA
GTTGATGATTTTACGGCGGATACTTAATATGCGCAAACCTTTTGAAATAATTTCTAAGAAGCCGATTAAC
GACAATGCATCCATCGGATAAAGGCTTTTAAAACCAGCGGCTGCCATTTTTGGTCCACCAATACCTTCAA
TAATTGCATTAGGGTATTTTTGCTTTAAAGCCTCAACTAGTGTGCCACCTAACTGATCGCCCGAAAGCTC
TCCAGCTACAATACCTATTCTCA
Protein Sequence 
>gi|56708594|ref|YP_170490.1| lipid-A-disaccharide synthase [Francisella tularensis subsp. tularensis SCHU S4] MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a lpxB mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0763M, under M: Cell wall/membrane/envelope biogenesis
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].