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apt

Victor ID 664
Gene Name apt
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191768
NCBI Protein GI 56707257
Locus Tag FTT0078
Protein Accession YP_169153.1
Other Database IDs UniProtKB-ID: APT_FRATT
UniRef100: UniRef100_Q14JZ2
UniRef90: UniRef90_Q14JZ2
UniRef50: UniRef50_C1F3T2
UniParc: UPI000049C1C1
EMBL: AJ749949
EMBL-CDS: CAG44711.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG703830
OMA: GILFYDI
ProtClustDB: PRK02304
Taxonomy ID 177416
Gene Starting Position 81534
Gene Ending Position 82061
Gene Strand (Orientation) +
Protein Name adenine phosphoribosyltransferase
DNA Sequence 
>gi|56707187:81534-82061 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGAACTTAGATTTTATTAAGAGTAAGATTGCAGCTGTGCCTGATTTTCCAAAACCAGGAATTATGTTT
CGCGACATTACTCCTTTGCTTGCAGATCCACAAGGACTCAGAAAAACTGCTGAGGCAATGGCACAAGAGT
TAAAAAACAAAGGTATCCAACCAACTATTGTTGCTGGTACAGAAAGTAGAGGTTTTATCTTTGGTGTTGC
TCTTGCTGAAGTATTAGGTCTGGGCTTTGTACCTGTCAGAAAGCCTGGCAAGCTACCAAGAGCAACTTAT
AGCGTTAAGTATGACCTAGAATATGGCAGTGATAGTCTTGAAATACATCAAGATGCCTTTAAAGTTACAG
ATGAGGTATTGGTGGTTGATGATTTATTGGCAACTGGTGGTACTGCAAAAGCAACAGTAGATCTTATAGA
AAAAACCCAAGCAAAAGTCGCAGGACTTATATTTGTGATGGAGCTTGATGGTTTGGGTGGTAGAGAAGTA
CTTGCTGGATACAATGTTTCAGCATTAATAAAATTCTA
Protein Sequence 
>gi|56707257|ref|YP_169153.1| adenine phosphoribosyltransferase [Francisella tularensis subsp. tularensis SCHU S4] MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: apt mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0503F, under F: Nucleotide transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].