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qseC

Victor ID 641
Gene Name qseC
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191649
NCBI Protein GI 56707270
Locus Tag FTT0094c
Protein Accession YP_169166.1
Other Database IDs UniProtKB-ID: Q5NIH6_FRATT
UniRef100: UniRef100_Q14JX9
UniRef90: UniRef90_A7NEE0
UniRef50: UniRef50_B0TWW8
UniParc: UPI000049C1CA
EMBL: AJ749949
EMBL-CDS: CAG44727.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG482277
OMA: CARQRED
ProtClustDB: CLSK934362
Taxonomy ID 177416
Gene Starting Position 97680
Gene Ending Position 99107
Gene Strand (Orientation) -
Protein Name sensor histidine kinase
DNA Sequence 
>gi|56707187:97680-99107 Francisella tularensis subsp. tularensis Schu 4, complete genome
TTTAATTTTCTTCGTATTTATGATCTATAGGAATTTTGACAGTAATGGTTAAGCCTTTTTGGTTGATATT
GTTTTGAGCAAAAATTTTACCATTATGAAGCCTAACGATTTCTGCGACGATTGCTAAACCTAGTCCACTA
CCTTCTTCACCTGTGCCTGTTTCACGATAAAATCTATCAAAAATACGTTCGATATTCTCTTGAGGTACGC
CAATACCATTATCTTTTATCTCGACGACTATATTGTTTTCCTCTTGATATGAGCTAATCTCAATAAGTCC
GCCGTTTGGGGTATATTTGATAGCATTTGAAATCAGATTTTTAAATAGTATCCCAAGTAGGTAGTCATTG
CTGTAACAGTATAAATGTTGTTGCGATGGATAAAATACTATTTCAATATTTTTCTCTATAGCTTTGATAG
CATTCTCGGCAATAAAGGATTCAAGAACCTTATTTATCATAAGTTTCTTACCGAATGTAACTTGTTCATT
GGGTTGAATCCTACTTAATGTTAATAATTGATCAATAATATGAGAATATCTGTTTGTTGAGCTTTTGATC
CGTTCAAGCTTTTGTTTGATTTCATCTATATCGTCTGATGCTAGAGCTATTTCTACAAGTGTTTTAACTC
CAGCTATTGGGGTTTTAAGCTCATGGGCTGCATCACCAGAGAAACGCTTTTCTCTCTCGAGAGTTTCGTG
GAACTTTTCAATAAGTAAATTAATTTGATCAACAATAGATTTTATTTCATAAGGTATAACATCTTCATTG
AGCTTTTCATTTTTACGAGGATTTATTTTAGCAACGCGTTTGTTTATACGCTCTAGTGGATGAAGAGCAG
TTTTTAATATATAGTAGATAAATCCAATAAGCACAATATAGGTTGATGCTAAAAGTAGCGCAAATTTAAA
TATTATTTGGCGAGATATTTTGTCTTTAATAGTATCGTTAGCAAAAACCGTGATAAGATTACCATTATCA
GTTTTTAAAGTATAGGTATACCAGTTTTTCTGACCATCCTCTTCGTTAGTGTATACCCATTCAAATCCTG
TTGTAGATGTTATGCCATCATAGTTTTTGTGAAAGTTTGGTAAATTAGATGTCTTTAATAACAGCTTTTT
GTGCTTTCGATCGTATACAATAAAGCCGATACTCTTATTGTAGTTTTTTATATTTAAAAAAGAATTCGAG
ATTCTATTCATTATCATATGAGTAGTATTTTCATCATCTTCTAAAGGATAAATTTTCAGTACAGTTTCGA
TAACTTCCGCAGCAGTTCTTAGCTGATAGTCAAGGAGCGAATCATTTTGATGCTTAACTTGATAGAAACT
AAAAATTGATATAACCAACATAAACACTGCAAAAAAGCTTGCAAAAGAAACGACAAGAAAACTTAGTATC
GAGCTTTCTTTTTTGTTTTTCAAAAACA
Protein Sequence 
>gi|56707270|ref|YP_169166.1| sensor histidine kinase [Francisella tularensis subsp. tularensis SCHU S4] MFLKNKKESSILSFLVVSFASFFAVFMLVISIFSFYQVKHQNDSLLDYQLRTAAEVIETVLKIYPLEDDENTTHMIMNRISNSFLNIKNYNKSIGFIVYDRKHKKLLLKTSNLPNFHKNYDGITSTTGFEWVYTNEEDGQKNWYTYTLKTDNGNLITVFANDTIKDKISRQIIFKFALLLASTYIVLIGFIYYILKTALHPLERINKRVAKINPRKNEKLNEDVIPYEIKSIVDQINLLIEKFHETLEREKRFSGDAAHELKTPIAGVKTLVEIALASDDIDEIKQKLERIKSSTNRYSHIIDQLLTLSRIQPNEQVTFGKKLMINKVLESFIAENAIKAIEKNIEIVFYPSQQHLYCYSNDYLLGILFKNLISNAIKYTPNGGLIEISSYQEENNIVVEIKDNGIGVPQENIERIFDRFYRETGTGEEGSGLGLAIVAEIVRLHNGKIFAQNNINQKGLTITVKIPIDHKYEEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: qseC mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0642T, under T: Signal transduction mechanisms
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].