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ribB

Victor ID 635
Gene Name ribB
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191625
NCBI Protein GI 56708682
Locus Tag FTT1672
Protein Accession YP_170578.1
Other Database IDs UniProtKB-ID: Q5NEG4_FRATT
UniRef100: UniRef100_A4J086
UniRef90: UniRef90_A7N9B0
UniRef50: UniRef50_A0Q459
UniParc: UPI000044FF93
EMBL: AJ749949
EMBL-CDS: CAG46305.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG289809
OMA: DEIGGHS
ProtClustDB: PRK09289
Taxonomy ID 177416
Gene Starting Position 1741689
Gene Ending Position 1742294
Gene Strand (Orientation) +
Protein Name riboflavin synthase subunit alpha
DNA Sequence 
>gi|56707187:1741689-1742294 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGTTTAGTGGCATAGTTCAGCAACTAGGAACAATTAAAAAAATAACAACTAAAGATAGTCTAAAAACT
TTTTGTATCAAATTTGATAATAGTCTTCAATGTAGCATTGGTGATAGTGTTGCGATTAATGGTACCTGTC
TTACTGTTACAAAACTTGATAAGCAAAACTTAACAGCTAATTTTGATGCAGTACCAGAGACACTTAAAAA
AACTAATCTTGATACTCTTAAGGAGAACCAACTAGTAAATATCGAACTTGCAATGCGCTATGGTGATCAT
ATTGGTGGGCATATGGTACAAGGTCATATTGATGAACCAGGGCAAATCAAAAGTATTCAAAATGTTGGTG
GTGCATGGTTAATTGAAATTTCTGCTTCTAGAGAATTTCTAAAATACTTAGTAAAGAAAGGTTTTGTAAC
TATAGATGGTATGAGTATAACTGTAATAAATGTACTCAAAGATTCATTTACTGTAACTTTGATACCTCAC
ACCATTGAAGTTACTATCGCAAAAAACTATAGTAATGGTTCTATGGTAAATCTTGAAGCTGATGCAACAG
GTAAATATATCTATAAATATATACAAGGATTTAAAGAAAATGTTTG
Protein Sequence 
>gi|56708682|ref|YP_170578.1| riboflavin synthase subunit alpha [Francisella tularensis subsp. tularensis SCHU S4] MFSGIVQQLGTIKKITTKDSLKTFCIKFDNSLQCSIGDSVAINGTCLTVTKLDKQNLTANFDAVPETLKKTNLDTLKENQLVNIELAMRYGDHIGGHMVQGHIDEPGQIKSIQNVGGAWLIEISASREFLKYLVKKGFVTIDGMSITVINVLKDSFTVTLIPHTIEVTIAKNYSNGSMVNLEADATGKYIYKYIQGFKENV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ribB mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0307H, under H: Coenzyme transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].