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rluC

Victor ID 633
Gene Name rluC
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191616
NCBI Protein GI 56707234
Locus Tag FTT0055
Protein Accession YP_169130.1
Other Database IDs UniProtKB-ID: Q5NIL2_FRATT
UniRef100: UniRef100_A0Q8E8
UniRef90: UniRef90_Q0BK75
UniRef50: UniRef50_B0TWR8
UniParc: UPI000049C1AE
EMBL: AJ749949
EMBL-CDS: CAG44688.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG750656
OMA: VKLPLYK
ProtClustDB: CLSK934350
Taxonomy ID 177416
Gene Starting Position 57314
Gene Ending Position 58243
Gene Strand (Orientation) +
Protein Name ribosomal large subunit pseudouridine synthase C
DNA Sequence 
>gi|56707187:57314-58243 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGAATAAGGTTGAGCTTATTGAGGTTGCAGAGGATGTAATAGATCAACGTATAGATAATTTTCTTTTA
AGTAGATTTTCTCGATTACCAAAATCTTTAATTTATCGCTGGATTCGCAAAGGCGAATTACGTGTAAATA
AAAAAAGAGTAAAACAGACATCACGTGTAAGTGCGGGAGATATTGTTAGAGTGCCTCCATTTAGTTTAGA
AGAAGATTCTAAACCTATAAAAATTTCACAATCACACTTGGACTTTCTAGAGCAGCGTATCCTATATGAG
AATGATGATTATATAATCGTTGATAAACCATCAGGTATGGCAGTGCATGGTGGTTCTGGAGTTAACTCAG
GATTAGTTGAGCGTCTAAGGCAGTTGCGTCCAAAAGTTAGACGTTTAGATTTAGTGCATAGACTTGATAA
AGAAACATCAGGCTGTGTACTTTTGGCAAAGAAACATAGTTCATTAGTATATTTCTTTGATATTTTCAAA
CAACGTAAGGTTGATAAAATTTATTATGCAATAGTTCATGGTCATTGGGATAAAAAAATCATTAAGATAG
ATTTACCTTTAAAAAGAACTGAAACTAAAGATGGCCAACGCGTTGTTAAAGTTGATAGTAAGGATGGAAA
ACAAGCTTTGACTAGGATTATATCGGTTAGGCATCTACAAGGAGGTTTTAGTCTACTTGAGATAAAGTTA
GAAACAGGTAGAACCCATCAAATTAGAGTACATACAAAAGCGATGGGGCATCCTATTGTTGCAGATAAGA
AGTATGGCTTTGCTACTAAAGATCAACTCTTGCTAGACAAGGGAGTTGATAGATTATTATTGCATGCAGC
TAAGTTAGAGTTCTATGATGATAAACAAAACAAGCAAATATCAGTAACAGCAGCATTAGATTCGCGATTT
GAGAAATTTATCCAAGAGTA
Protein Sequence 
>gi|56707234|ref|YP_169130.1| ribosomal large subunit pseudouridine synthase C [Francisella tularensis subsp. tularensis SCHU S4] MNKVELIEVAEDVIDQRIDNFLLSRFSRLPKSLIYRWIRKGELRVNKKRVKQTSRVSAGDIVRVPPFSLEEDSKPIKISQSHLDFLEQRILYENDDYIIVDKPSGMAVHGGSGVNSGLVERLRQLRPKVRRLDLVHRLDKETSGCVLLAKKHSSLVYFFDIFKQRKVDKIYYAIVHGHWDKKIIKIDLPLKRTETKDGQRVVKVDSKDGKQALTRIISVRHLQGGFSLLEIKLETGRTHQIRVHTKAMGHPIVADKKYGFATKDQLLLDKGVDRLLLHAAKLEFYDDKQNKQISVTAALDSRFEKFIQE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rluC mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0564J, under J: Translation, ribosomal structure and biogenesis
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].