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xerC

Victor ID 630
Gene Name xerC
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191568
NCBI Protein GI 56708541
Locus Tag FTT1503
Protein Accession YP_170437.1
Other Database IDs UniProtKB-ID: Q5NEV5_FRATT
UniRef100: UniRef100_A7N9Y2
UniRef90: UniRef90_A7N9Y2
UniRef50: UniRef50_B0TX96
UniParc: UPI000049C565
EMBL: AJ749949
EMBL-CDS: CAG46136.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG727654
OMA: TTEGIRD
ProtClustDB: CLSK935057
Taxonomy ID 177416
Gene Starting Position 1557983
Gene Ending Position 1558861
Gene Strand (Orientation) +
Protein Name Integrase/recombinase XerC
DNA Sequence 
>gi|56707187:1557983-1558861 Francisella tularensis subsp. tularensis Schu 4, complete genome
TATGACTAATTTAGAGCATATCAATAATTTTCTTGACAACTTACTTTATCTTAAAAACTATTCTCAAGAA
ACTATTAATAACTATCAAAGGGATCTATTGCAACTAAATCAAGCTCTTAGTGATAAAAATATTATTAGTT
TAACTCATAGTGATATATTGATATGGATAAAAAAGCTACATGCTCAAGGCAATTCTCCTAAGACACTCCA
GCGTAAACTTAGTTCAGTTAGAAGCTTTTTTAATTTTCTCATAAATAGCGAAATAGTATCACAAAATCCA
GCTAACGGTATCAAAGCACCTAAAGATAGCAAAAGACTACCCAAAGTAGTCAACACAGATGAATTGGCAT
ATCTACTAGATATAAATCCAAGCAATGATATTGAAGCTCGTGATATTGCCTGTTTTGATCTGTTGTATAG
TTGTGGCATTAGACTTAGTGAATTATCATCAGTTGAACTAAAAGATATAAGCATATCACAAAAAAATATT
CGTGTTACAGGCAAAGGCAACAAACAACGTATTGTATACTTTGGTACCAAAACCTTAAGTAACCTCAATA
GATGGCTCAAAATCAGAGATAGCTTAAAACCAAGCAGTGATTATCTATTTATTTCCCGTGATGGTAAACA
CTTGACAAATAGATCAATTCAAAAGCGTCTTGAAATATTCGCTCAAAAATATGCTAGCCGCCATATCCAT
CCACATATGCTAAGGCATTCTTTTGCTAGTCATGTACTTGATTCATCTAAAGATCTATTAGCTGTGAAAG
ATTTATTGGGTCATGCTGATATTTCTAGTACACAGATATACACACATTTAAATTTCCAACAACTAGCAAG
CGTTTTTGATAAAGCGCACCCTCGGGCAAAGAAAAAATA
Protein Sequence 
>gi|56708541|ref|YP_170437.1| integrase/recombinase XerC [Francisella tularensis subsp. tularensis SCHU S4] MTNLEHINNFLDNLLYLKNYSQETINNYQRDLLQLNQALSDKNIISLTHSDILIWIKKLHAQGNSPKTLQRKLSSVRSFFNFLINSEIVSQNPANGIKAPKDSKRLPKVVNTDELAYLLDINPSNDIEARDIACFDLLYSCGIRLSELSSVELKDISISQKNIRVTGKGNKQRIVYFGTKTLSNLNRWLKIRDSLKPSSDYLFISRDGKHLTNRSIQKRLEIFAQKYASRHIHPHMLRHSFASHVLDSSKDLLAVKDLLGHADISSTQIYTHLNFQQLASVFDKAHPRAKKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: xerC mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG4973L, under L: Replication, recombination and repair
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].