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gcvH

Victor ID 627
Gene Name gcvH
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191553
NCBI Protein GI 56707557
Locus Tag FTT0408
Protein Accession YP_169453.1
Other Database IDs UniProtKB-ID: Q5NHN9_FRATT
UniRef100: UniRef100_A4IZK7
UniRef90: UniRef90_A0Q586
UniRef50: UniRef50_A4IZK7
UniParc: UPI0000450157
EMBL: AJ749949
EMBL-CDS: CAG45041.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG693789
OMA: DVYAPIT
ProtClustDB: CLSK934505
Taxonomy ID 177416
Gene Starting Position 414911
Gene Ending Position 415294
Gene Strand (Orientation) +
Protein Name glycine cleavage system H protein
DNA Sequence 
>gi|56707187:414911-415294 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGTCAAATATTCCTAAAGAATTAAAGTATACAAAGTCGCATGAGTGGGTCAAAATAGATGGTGATGAA
GTCACTGTAGGTATTACAGCACATGCACAATCTTTATTGGGCGATTTAGTCTATGTTGAATTACCAGAAA
TAGGCAAAGAGTTCGCAGCTGGTGATGATTCTTGTGTGGTTGAGTCTGTCAAAGCAGCCTCTGATGTATA
CGCTCCTGTTGATGGTGAGGTAATTGAAATTAATGAAGCTTTGGTTGATGACCCTTCACGAGTCAATCAT
ACACCATATAAAGATGGCTGGCTATTTAAACTTAAAATCTCTGATGAATCTCAGTTAGCTGATTTGCTAA
CAGCTGATGCTTATGCAAAAACTCTTGAGGATTA
Protein Sequence 
>gi|56707557|ref|YP_169453.1| glycine cleavage system H protein [Francisella tularensis subsp. tularensis SCHU S4] MSNIPKELKYTKSHEWVKIDGDEVTVGITAHAQSLLGDLVYVELPEIGKEFAAGDDSCVVESVKAASDVYAPVDGEVIEINEALVDDPSRVNHTPYKDGWLFKLKISDESQLADLLTADAYAKTLED
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gcvH mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0509E, under E: Amino acid transport and metabolism
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].