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cca

Victor ID 625
Gene Name cca
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191540
NCBI Protein GI 56707282
Locus Tag FTT0108c
Protein Accession YP_169178.1
Other Database IDs UniProtKB-ID: CCA_FRATT
UniRef100: UniRef100_Q14JW7
UniRef90: UniRef90_A0Q8A2
UniRef50: UniRef50_A0Q8A2
UniParc: UPI000049C1D2
EMBL: AJ749949
EMBL-CDS: CAG44741.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG635063
OMA: ISTARNE
ProtClustDB: PRK13296
Taxonomy ID 177416
Gene Starting Position 114236
Gene Ending Position 115318
Gene Strand (Orientation) -
Protein Name tRNA CCA-pyrophosphorylase
DNA Sequence 
>gi|56707187:114236-115318 Francisella tularensis subsp. tularensis Schu 4, complete genome
ATCATAGTTTTAGCTGCTTTAGCGTGTTTCTGAGTTTATCTTTAGGTATTGTTTTTATCGTCAAACTATC
AATGCTTGCATTTTTAATTGTATTAATAGTAGTTTGTAATAGTTGATAATTCCTATGTGGAGTTATAGTA
TCGCATATCTTTAGATATTTTTTATAGAGATTTAAACTCTCGGCAAATAAATTTTTGTCACGGATAATAT
TAGCGTTTTTGATTAGTTGAAATATCTCTTCAGCAGTGATACTTCTATCTTCGAGTATTTTGCTGATAGC
TATGCTTGCTTTTAAAAGTTTGTAGTGTTTATTTGTTAATAAAAATTCCTTTCTGATATCATCTAATTGT
TGTTGTGGGATCTTGAGTAAACATAGCGTTATTTTTTCATTGATATTAGAGCCTTTATAGATGGGGTTTT
CAAAAAAAGATTTATTTGGTATTAGTGGTAAAAAGCAGCTGATATTTGGAAATATTATTTTTAAAGCTTC
TAGTTCTTTGAGTGTCGTAAAGAAGATCTTGGGATTGTTAAGAGCTTTGACAAACTCTATATGTAATCTT
TCACGCGTTAAATGATTTAATTCACCTGTTTTAACTAACTCTTTTATAAGTGCCAGCATTTCTTGGGCTA
TTGAGAAATTGAAGTTACTAAGTTGAGCCTTGAAACGCGCAAGTCTAACTACACGCAGTGGGTCTTCGAT
AAAGGCTATTGAAGTATGGCGTAAAATTCTATTTTGAAGATCGGCTTGGCCATTAAAAGGGTCAATTACT
TTATTATTTTGATCGATTGCTATTGAGTTAATTGTGAGATCACGACGTTTAAGATCGTCTTCTAGAGTTA
TATATTTTGAAAAATTAACTTCAAAGCCATGATAGCCACTGGCAGTTTTCTTTTCTGACCTTGCTAAAGC
ATACTCTTGTTTGGTTTGTGGGTGGATAAAAACTGGGAAGTTGGCTGCTATTTTTATAAATCCATTTGCT
AGCATCTCGTCTTCAGTTGCACCAACAACTACCCAATCCTTGTCTTTAGGTGTTATGCCTAACAACATAT
CTCTAACGGCGCCACCAACTAAGTAAAATTTCA
Protein Sequence 
>gi|56707282|ref|YP_169178.1| tRNA CCA-pyrophosphorylase [Francisella tularensis subsp. tularensis SCHU S4] MKFYLVGGAVRDMLLGITPKDKDWVVVGATEDEMLANGFIKIAANFPVFIHPQTKQEYALARSEKKTASGYHGFEVNFSKYITLEDDLKRRDLTINSIAIDQNNKVIDPFNGQADLQNRILRHTSIAFIEDPLRVVRLARFKAQLSNFNFSIAQEMLALIKELVKTGELNHLTRERLHIEFVKALNNPKIFFTTLKELEALKIIFPNISCFLPLIPNKSFFENPIYKGSNINEKITLCLLKIPQQQLDDIRKEFLLTNKHYKLLKASIAISKILEDRSITAEEIFQLIKNANIIRDKNLFAESLNLYKKYLKICDTITPHRNYQLLQTTINTIKNASIDSLTIKTIPKDKLRNTLKQLKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cca mutant is attenuated in mouse spleen (Weiss et al., 2007).
COG COG0617J, under J: Translation, ribosomal structure and biogenesis
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].