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htpG

Victor ID 619
Gene Name htpG
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3191490
NCBI Protein GI 56707508
Locus Tag FTT0356
Protein Accession YP_169404.1
Other Database IDs UniProtKB-ID: HTPG_FRATT
UniRef100: UniRef100_Q14J90
UniRef90: UniRef90_B0U0M7
UniRef50: UniRef50_B0U0M7
UniParc: UPI000049C277
EMBL: AJ749949
EMBL-CDS: CAG44989.1
RefSeq_NT: NC_006570.2
GenomeReviews: AJ749949_GR
HOGENOM: HBG631012
OMA: AIYYITA
ProtClustDB: PRK05218
Taxonomy ID 177416
Gene Starting Position 355151
Gene Ending Position 357037
Gene Strand (Orientation) +
Protein Name heat shock protein 90
DNA Sequence 
>gi|56707187:355151-357037 Francisella tularensis subsp. tularensis Schu 4, complete genome
AATGTCAGAAAAAAAATATACTTTTGAAACTGAGGTAGATAAATTACTTCATCTTGTAATTCACTCACTA
TATTCAAACCGTGAGATATTTTTAAGAGAACTTGTATCTAATAGTTCTGATGCTATCGAGAAATTAAGAT
ATGAGAGTATTTCAAACGCAGCTTTAAACGAAGATGATACTGATTATGCTATCAGAATTGATTTTGATAA
AGATGCAAAAACTATAACAGTTAGCGATAATGGTATCGGTATGACTGAAGAAGAAGTCATCGAAAATCTC
GGCACAATTGCTAAGTCAGGGACTAAGAAATTCTTAGAAAGTTTAACTGGTGATAAGAGCAAAGATAACG
AGCTGATTGGTCAGTTTGGAGTTGGTTTTTATTCATCATTTATAGTTGCTGATAAAGTTACGGTTAGAAC
TAGAAAAGCAGGTCAAGATAAATCTCAAGCTACTAAGTGGGTTTCTGATGCACAGAATGGTTTTACAGTA
GAGACAATAACTAAAGAAAAGCGTGGTACAGAAGTAATTCTTCATATTAAGAAAGAACATTTGGATTTGC
TAGAATATCACGTGCTTAAAGGTTTAGTCAATAAGTACTCAGATTGTATCAATACATCAATTCAGATGAA
GAAGGTTGAGTATGATAAAGATGGTAAGCAAACTGTTAAAGATGAATATGAAACAGTAAATAATACTAAA
GCTATTTGGCTAAGATCTAAAGATGAAGTTACTGATGAGGAATATCAAGAGTTCTATAAGTATATTTCCC
ATGATTTTGCTGATGCTTTAATGTGGATACATAATAAGGTTGAAGGTAATCTTGAATATAATAGCTTACT
TTATATTCCACAAAATAAACCTTTTGATTTCTGGAACAGAGATAAAGACTATGGTTTATCACTGTATGTG
CGTAGAGTCTTTATTATGGAGAATAAGGAATTATTACCTCCATATTTAAGATTTGTTAAGGGTGTCATTG
ATTCTGCTGATTTACCACTTAATGTATCACGTGAGATATTACAGCATAATAAAGTTATTGATAAGATTAA
AAAAGCAATAACGACTAAAATCCTAAGTGAACTTAAGAAGCTAGCTAGTAAGGATAAAGAAAAATACCAA
AAATTCTGGGATAGTTTTGGTCAAGTGCTTAAAGAAGGTGTTTCTGATGATTACTCAAACAAGGAAAAGA
TTGCGGGCTTATTAAGATTTGCTACTACTCAAAGTGGCGACTCTAAGCAAACAGTATCTTTGGCTGATTA
TATTTCGCGTATGAAAGAAGGTCAAGATACTATTTACTATATTACTTCTGATAGTTATAAGGCTGCTGCG
AATAATCCACAGCTTGAAGCATTCAAGAAGAAAGGTATCGAGGTTATCTTGATGACAGATAGAATCGATG
AATGGATGATGTCTACTTTGACTGAGTTTGATGGCAAGCATATGAAATCAATTATCAAAGGTGATATTGA
TCTTGATAGGTTTGAAACTCCAGAGAACAAAGAGAAATTTGAGAAAGAAGCGAAAGACTTTGAGAAAGTT
CTAAAAGAAATTAAAGAAGTTCTAAAAGATAAGGTCGAGGATGTACGTCTATCTAAGCGTCTGACAGATT
CTCCAAGTTGTGTGGTTGTTAATGACTATGGTATGAGTCTACACATGCAAAAGATGATGGAAGAGGCTGG
ACAGTCATTTATGCCTGGTATGGGTATGAAACCAATCCTTGAGCTTAATGCTGAGCATAATTTGGTGCAG
AAGCTTAAAAATGAAGCAGATACAGAAATATTTGCTGATTTATCTGAGCTTTTACTTCTTCAAGCTATGT
TTGTAGAAGGTGCTAAGATAGAAGATCCAATGGCTTTTGTTAAGCTTGTGAATAAATATATCAGATA
Protein Sequence 
>gi|56707508|ref|YP_169404.1| heat shock protein 90 [Francisella tularensis subsp. tularensis SCHU S4] MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVETITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTSIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKDEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKHMKSIIKGDIDLDRFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAGQSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: htpG mutant is strongly attenuated in mice (Weiss et al., 2007).
COG COG0326O, under O: Posttranslational modification, protein turnover, chaperones
References
Weiss et al., 2007: Weiss DS, Brotcke A, Henry T, Margolis JJ, Chan K, Monack DM. In vivo negative selection screen identifies genes required for Francisella virulence. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(14); 6037-6042. [PubMed: 17389372].