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MT3523

Victor ID 61
Gene Name MT3523
Sequence Strain (Species/Organism) Mycobacterium tuberculosis CDC1551
NCBI Gene ID 923111
NCBI Protein GI 15843010
Locus Tag MT3523
Protein Accession NP_338047.1
Other Database IDs UniProtKB-ID: RPSD_MYCTU
UniRef100: UniRef100_P66812
UniRef90: UniRef90_P66812
UniRef50: UniRef50_P66812
UniParc: UPI0000134831
EMBL: BX842583
EMBL: AE000516
EMBL-CDS: CAB01009.1
EMBL-CDS: AAK47861.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000002804
EnsemblGenome_TRS: EBMYCT00000002806
EnsemblGenome_PRO: EBMYCP00000002806
EnsemblGenome: EBMYCG00000070992
EnsemblGenome_TRS: EBMYCT00000070997
EnsemblGenome_PRO: EBMYCP00000069056
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83331
Gene Starting Position 3823914
Gene Ending Position 3824588
Gene Strand (Orientation) -
Protein Name RNA polymerase sigma factor SigD
DNA Sequence 
>gi|50953765:3823914-3824588 Mycobacterium tuberculosis CDC1551, complete genome
TTCACGCATAGTCACCTGCCGCAACAATCTCGTCCTTCAGCCGCTGAAGTGCACGGTGTTGGGCCACCCG
GACCGCCCCCGTGGTGCTGCCGACGGCGGCGGCGGTCTCTTCCGCGGACAGGCCGACGACAACACGCAGA
ATGAGGATCTCGCGTTGCTTGGCCGGCAAGATCTCAAGCAATTCGTTCATCCGGGTGACCGAATCGGCCT
CGATGGCCATCTGCTCCGGGCCGGCGTCGGCTGACCAGCGCTCAGGAAGCGTTTCGGCGGGATAGGCCCG
GTCACGGCCGGCTGCCCGATGGGCGTCGGCAACCTTGTGCGCCGCGATGCCGTACAGAAACGCCAGGAAT
GGCCGGCCGCGGTCCCGATAGCGCGGCAGCGCCGTTATGGTGGCCAAGCACACCTCCTGTGCCACGTCAT
CTGCTGACAGGCCGCTCCGCTCGACCGTGCCGACTCGCGCTCGGCAATATCGCACGACGATCGGGCGGAT
GGTCTCCAGCACCTCCCGAAGCGCGTTCCGGTCTCCTGCCACGGCCTCCGCAACCACAGCGTCGAGACGT
TCCCCTTGCATTGTCATCGACGGCGATATCTCCAACGTTACGAAGCGGACACATCCCGGGCTAACTCCCG
GATCGACCATAACGGCCCAACCGCGTTTTAAGCGGTACGCCAGCA
Protein Sequence 
>gi|15843010|ref|NP_338047.1| RNA polymerase sigma factor SigD [Mycobacterium tuberculosis CDC1551] MLAYRLKRGWAVMVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLETIRPIVVRYCRARVGTVERSGLSADDVAQEVCLATITALPRYRDRGRPFLAFLYGIAAHKVADAHRAAGRDRAYPAETLPERWSADAGPEQMAIEADSVTRMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGAVRVAQHRALQRLKDEIVAAGDYA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigD mutant is attenuated in human macrophages and mice (Calamita et al., 2005).
COG COG1595K, under K: Transcription
References
Calamita et al., 2005: Calamita H, Ko C, Tyagi S, Yoshimatsu T, Morrison NE, Bishai WR. The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence. Cellular microbiology. 2005; 7(2); 233-244. [PubMed: 15659067].